In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T

Detalhes bibliográficos
Autor(a) principal: Duarte,Marcia Adriana Tomaz
Data de Publicação: 2014
Outros Autores: Duek,Eliana Aparecida de Rezende, Motta,Adriana Cristina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Polímeros (São Carlos. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282014000100002
Resumo: The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by producing PLDLA/PCL-T blends with 90/10, 70/30 and 50/50 relative concentrations. The data for in vitro degradation showed that PCL-T decreases the rate of PLDLA. This was obtained with the following techniques: Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Gel Permeation Chromatography (GPC) and Scanning Electron Microscopy (SEM). Therefore, it is possible to vary the membrane degradation rate by changing the blend composition, which is a tool to tailor a biomaterial.
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spelling In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-TBioresorbable polymerin vitro degradationPLDLA/PCL-TThe application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by producing PLDLA/PCL-T blends with 90/10, 70/30 and 50/50 relative concentrations. The data for in vitro degradation showed that PCL-T decreases the rate of PLDLA. This was obtained with the following techniques: Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Gel Permeation Chromatography (GPC) and Scanning Electron Microscopy (SEM). Therefore, it is possible to vary the membrane degradation rate by changing the blend composition, which is a tool to tailor a biomaterial.Associação Brasileira de Polímeros2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282014000100002Polímeros v.24 n.1 2014reponame:Polímeros (São Carlos. Online)instname:Associação Brasileira de Polímeros (ABPol)instacron:ABPO10.4322/polimeros.2014.056info:eu-repo/semantics/openAccessDuarte,Marcia Adriana TomazDuek,Eliana Aparecida de RezendeMotta,Adriana Cristinaeng2014-04-03T00:00:00Zoai:scielo:S0104-14282014000100002Revistahttp://www.scielo.br/pohttps://old.scielo.br/oai/scielo-oai.php||revista@abpol.org.br1678-51690104-1428opendoar:2014-04-03T00:00Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)false
dc.title.none.fl_str_mv In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
title In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
spellingShingle In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
Duarte,Marcia Adriana Tomaz
Bioresorbable polymer
in vitro degradation
PLDLA/PCL-T
title_short In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
title_full In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
title_fullStr In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
title_full_unstemmed In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
title_sort In vitro degradation of poly (L-co-D,L lactic acid) containing PCL-T
author Duarte,Marcia Adriana Tomaz
author_facet Duarte,Marcia Adriana Tomaz
Duek,Eliana Aparecida de Rezende
Motta,Adriana Cristina
author_role author
author2 Duek,Eliana Aparecida de Rezende
Motta,Adriana Cristina
author2_role author
author
dc.contributor.author.fl_str_mv Duarte,Marcia Adriana Tomaz
Duek,Eliana Aparecida de Rezende
Motta,Adriana Cristina
dc.subject.por.fl_str_mv Bioresorbable polymer
in vitro degradation
PLDLA/PCL-T
topic Bioresorbable polymer
in vitro degradation
PLDLA/PCL-T
description The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by producing PLDLA/PCL-T blends with 90/10, 70/30 and 50/50 relative concentrations. The data for in vitro degradation showed that PCL-T decreases the rate of PLDLA. This was obtained with the following techniques: Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Gel Permeation Chromatography (GPC) and Scanning Electron Microscopy (SEM). Therefore, it is possible to vary the membrane degradation rate by changing the blend composition, which is a tool to tailor a biomaterial.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282014000100002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-14282014000100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.4322/polimeros.2014.056
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Polímeros
publisher.none.fl_str_mv Associação Brasileira de Polímeros
dc.source.none.fl_str_mv Polímeros v.24 n.1 2014
reponame:Polímeros (São Carlos. Online)
instname:Associação Brasileira de Polímeros (ABPol)
instacron:ABPO
instname_str Associação Brasileira de Polímeros (ABPol)
instacron_str ABPO
institution ABPO
reponame_str Polímeros (São Carlos. Online)
collection Polímeros (São Carlos. Online)
repository.name.fl_str_mv Polímeros (São Carlos. Online) - Associação Brasileira de Polímeros (ABPol)
repository.mail.fl_str_mv ||revista@abpol.org.br
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