The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease

Detalhes bibliográficos
Autor(a) principal: Kunz,Vandeni C.
Data de Publicação: 2011
Outros Autores: Souza,Raquel B., Takahashi,Anielle C. M., Catai,Aparecida M., Silva,Ester
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Physical Therapy
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-35552011000600012
Resumo: BACKGROUND: A reduction in heart rate variability (HRV) is considered an important indicator of autonomic dysfunction. OBJECTIVES: The aims of this study were to evaluate the presence of autonomic dysfunction measured by HRV in patients with coronary artery disease (CAD) and to compare them with normal subjects. METHODS: A sample of 52 men (mean age 54±5.39 years) was allocated into three groups: obstructive CAD ≥50% (CAD+ n=18), obstructive CAD <50%, (CAD- n=17) and apparently healthy controls (CG n=17). Heart rate (HR) was measured at rest using a Polar®S810i for 15 min. HRV was analyzed via Shannon entropy (SE) and symbolic analysis (0V and 2ULV), which relate to sympathetic and vagal predominance, respectively. Statistical analysis included the Kruskal-Wallis test and multivariate analysis (p<0.05). RESULTS: The CAD+ group presented lower SE and 2ULV% values and higher 0V% compared to CAD- and control groups (p<0.05). In the multivariate analysis, the presence of the clinical characteristics such as myocardial infarction and revascularization in the CAD+ group lead to a lower SE and higher 0V compared to the CAD- group. The use of angiotensin converting enzymes led to a higher SE in the CAD- group compared to the CAD+ (p<0.05). CONCLUSION: In uncomplicated CAD+ patients the patterns of HRV have a lower complexity, a greater sympathetic modulation and a lower parasympathetic modulation compared to CAD- and control groups in supine resting conditions. These results indicate that autonomic heart dysfunction is related to the degree of coronary occlusion and cardiac compromise.
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spelling The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery diseasePhysical therapyheart ratecoronary artery diseasenonlinear dynamicsBACKGROUND: A reduction in heart rate variability (HRV) is considered an important indicator of autonomic dysfunction. OBJECTIVES: The aims of this study were to evaluate the presence of autonomic dysfunction measured by HRV in patients with coronary artery disease (CAD) and to compare them with normal subjects. METHODS: A sample of 52 men (mean age 54±5.39 years) was allocated into three groups: obstructive CAD ≥50% (CAD+ n=18), obstructive CAD <50%, (CAD- n=17) and apparently healthy controls (CG n=17). Heart rate (HR) was measured at rest using a Polar®S810i for 15 min. HRV was analyzed via Shannon entropy (SE) and symbolic analysis (0V and 2ULV), which relate to sympathetic and vagal predominance, respectively. Statistical analysis included the Kruskal-Wallis test and multivariate analysis (p<0.05). RESULTS: The CAD+ group presented lower SE and 2ULV% values and higher 0V% compared to CAD- and control groups (p<0.05). In the multivariate analysis, the presence of the clinical characteristics such as myocardial infarction and revascularization in the CAD+ group lead to a lower SE and higher 0V compared to the CAD- group. The use of angiotensin converting enzymes led to a higher SE in the CAD- group compared to the CAD+ (p<0.05). CONCLUSION: In uncomplicated CAD+ patients the patterns of HRV have a lower complexity, a greater sympathetic modulation and a lower parasympathetic modulation compared to CAD- and control groups in supine resting conditions. These results indicate that autonomic heart dysfunction is related to the degree of coronary occlusion and cardiac compromise.Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia 2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-35552011000600012Brazilian Journal of Physical Therapy v.15 n.6 2011reponame:Brazilian Journal of Physical Therapyinstname:Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia (ABRAPG-FT)instacron:ABRAPG-FT10.1590/S1413-35552011005000020info:eu-repo/semantics/openAccessKunz,Vandeni C.Souza,Raquel B.Takahashi,Anielle C. M.Catai,Aparecida M.Silva,Estereng2012-01-02T00:00:00Zoai:scielo:S1413-35552011000600012Revistahttps://www.scielo.br/j/rbfis/https://old.scielo.br/oai/scielo-oai.phpcontato@rbf-bjpt.org.br||contato@rbf-bjpt.org.br1809-92461413-3555opendoar:2012-01-02T00:00Brazilian Journal of Physical Therapy - Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia (ABRAPG-FT)false
dc.title.none.fl_str_mv The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
title The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
spellingShingle The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
Kunz,Vandeni C.
Physical therapy
heart rate
coronary artery disease
nonlinear dynamics
title_short The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
title_full The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
title_fullStr The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
title_full_unstemmed The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
title_sort The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease
author Kunz,Vandeni C.
author_facet Kunz,Vandeni C.
Souza,Raquel B.
Takahashi,Anielle C. M.
Catai,Aparecida M.
Silva,Ester
author_role author
author2 Souza,Raquel B.
Takahashi,Anielle C. M.
Catai,Aparecida M.
Silva,Ester
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Kunz,Vandeni C.
Souza,Raquel B.
Takahashi,Anielle C. M.
Catai,Aparecida M.
Silva,Ester
dc.subject.por.fl_str_mv Physical therapy
heart rate
coronary artery disease
nonlinear dynamics
topic Physical therapy
heart rate
coronary artery disease
nonlinear dynamics
description BACKGROUND: A reduction in heart rate variability (HRV) is considered an important indicator of autonomic dysfunction. OBJECTIVES: The aims of this study were to evaluate the presence of autonomic dysfunction measured by HRV in patients with coronary artery disease (CAD) and to compare them with normal subjects. METHODS: A sample of 52 men (mean age 54±5.39 years) was allocated into three groups: obstructive CAD ≥50% (CAD+ n=18), obstructive CAD <50%, (CAD- n=17) and apparently healthy controls (CG n=17). Heart rate (HR) was measured at rest using a Polar®S810i for 15 min. HRV was analyzed via Shannon entropy (SE) and symbolic analysis (0V and 2ULV), which relate to sympathetic and vagal predominance, respectively. Statistical analysis included the Kruskal-Wallis test and multivariate analysis (p<0.05). RESULTS: The CAD+ group presented lower SE and 2ULV% values and higher 0V% compared to CAD- and control groups (p<0.05). In the multivariate analysis, the presence of the clinical characteristics such as myocardial infarction and revascularization in the CAD+ group lead to a lower SE and higher 0V compared to the CAD- group. The use of angiotensin converting enzymes led to a higher SE in the CAD- group compared to the CAD+ (p<0.05). CONCLUSION: In uncomplicated CAD+ patients the patterns of HRV have a lower complexity, a greater sympathetic modulation and a lower parasympathetic modulation compared to CAD- and control groups in supine resting conditions. These results indicate that autonomic heart dysfunction is related to the degree of coronary occlusion and cardiac compromise.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-35552011000600012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-35552011000600012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1413-35552011005000020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia
publisher.none.fl_str_mv Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia
dc.source.none.fl_str_mv Brazilian Journal of Physical Therapy v.15 n.6 2011
reponame:Brazilian Journal of Physical Therapy
instname:Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia (ABRAPG-FT)
instacron:ABRAPG-FT
instname_str Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia (ABRAPG-FT)
instacron_str ABRAPG-FT
institution ABRAPG-FT
reponame_str Brazilian Journal of Physical Therapy
collection Brazilian Journal of Physical Therapy
repository.name.fl_str_mv Brazilian Journal of Physical Therapy - Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia (ABRAPG-FT)
repository.mail.fl_str_mv contato@rbf-bjpt.org.br||contato@rbf-bjpt.org.br
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