O uso de whey protein no manejo da síndrome consumptiva em pacientes HIV+

• Autor(a) principal: Naidu, Soujanya Talapala
• Data de Publicação: 2022
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: International Journal of Nutrology (Online)
• Texto Completo: https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/160
• topic: AIDS; HIV; wasting syndrome; weight loss; muscle mass; whey protein; exercise

The aim of the present study was to perform a systematic review of the available scientific literature regarding the use of whey protein (WP) in the management of HIV wasting syndrome. The following scientific repositories were searched: PubMed/Medline, Cochrane Central Register of Controlled Trials (CENTRAL), Scielo, ScienceDirect, Europe PubMed Central (Europe PMC), LILACS (BIREME) and BVSalud. Search parameters consisted of combinations of the terms HIV, wasting syndrome, muscle mass, and whey protein, in English, Portuguese and Spanish. From these filters, three articles were identified for analysis; one article was published in AIDS, one in BMJ, and the third was published in the American Journal of Clinical Nutrition. All three studies were quantitative in nature (100%), with a combined total of 407 participants (mean = 135.7). Study volunteers were mainly female (60.7%), and volunteers had no other pathologies that could lead to muscle wasting and were not receiving anabolic treatments. The studies were performed in the United States (n = 2) and Ethiopia (n = 1). One study analyzed the effects of WP alone, one compared WP to exercise and to an association between these two, and the third study compared WP to soy protein. The main research variables were weight (n = 3), body cell mass (n = 2), fat-free mass or lean mass (n = 3), fat mass (n = 2), and muscle strength (n = 2). The results of the three studies show that WP may lead to weight gain but has no significant effect on muscle mass in HIV/AIDS wasting syndrome.