Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease

Detalhes bibliográficos
Autor(a) principal: Cersosimo, Eugenio
Data de Publicação: 2022
Outros Autores: Oliveira, José Eduardo Dutra de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: International Journal of Nutrology (Online)
Texto Completo: https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39
Resumo: From a Nutrology point of view, type 2 diabetes is a multi-factorial form of clinical “malnutrition” resulting from the intake of an imbalanced diet in combination with adverse environmental conditions and in the presence of predisposing genetic factors. In this review article, we present evidence of a close association between clinical obesity in a specific genetic background as the pillars of the process underlying the development of type 2 diabetes. We review the basics of the energy balance and the role of fat storage and body distribution in the pathogenesis of insulin resistance. We describe some molecular aspects of nutrients under normal physiology and during the metabolic and hormonal abnormalities that accompany type 2 diabetes. We conclude with a brief discussion of the principles behind popular dietary recommendations aimed at preventing the full development of diabetes mellitus and its complications.
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spelling Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to diseaseType 2 DiabetesNutrient Patho-physiologyGenetics and ObesityFrom a Nutrology point of view, type 2 diabetes is a multi-factorial form of clinical “malnutrition” resulting from the intake of an imbalanced diet in combination with adverse environmental conditions and in the presence of predisposing genetic factors. In this review article, we present evidence of a close association between clinical obesity in a specific genetic background as the pillars of the process underlying the development of type 2 diabetes. We review the basics of the energy balance and the role of fat storage and body distribution in the pathogenesis of insulin resistance. We describe some molecular aspects of nutrients under normal physiology and during the metabolic and hormonal abnormalities that accompany type 2 diabetes. We conclude with a brief discussion of the principles behind popular dietary recommendations aimed at preventing the full development of diabetes mellitus and its complications.MetaScience Press2022-01-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articleapplication/pdfhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/3910.1055/s-0040-1701422International Journal of Nutrology; Vol. 5 No. 1 (2012): International Journal of Nutrology (IJN) - January 2012; 6-132595-28541984-301110.1055/s-010-45544reponame:International Journal of Nutrology (Online)instname:Associação Brasileira de Nutrologia (ABRAN)instacron:ABRANenghttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39/36Copyright (c) 2022 International Journal of Nutrologyinfo:eu-repo/semantics/openAccessCersosimo, EugenioOliveira, José Eduardo Dutra de2022-01-25T13:48:27Zoai:ojs2.ijn.zotarellifilhoscientificworks.com:article/39Revistahttps://ijn.zotarellifilhoscientificworks.com/index.php/ijnONGhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/oaiijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com10.544482595-28541984-3011opendoar:2022-01-25T13:48:27International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN)false
dc.title.none.fl_str_mv Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
title Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
spellingShingle Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
Cersosimo, Eugenio
Type 2 Diabetes
Nutrient Patho-physiology
Genetics and Obesity
title_short Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
title_full Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
title_fullStr Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
title_full_unstemmed Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
title_sort Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
author Cersosimo, Eugenio
author_facet Cersosimo, Eugenio
Oliveira, José Eduardo Dutra de
author_role author
author2 Oliveira, José Eduardo Dutra de
author2_role author
dc.contributor.author.fl_str_mv Cersosimo, Eugenio
Oliveira, José Eduardo Dutra de
dc.subject.por.fl_str_mv Type 2 Diabetes
Nutrient Patho-physiology
Genetics and Obesity
topic Type 2 Diabetes
Nutrient Patho-physiology
Genetics and Obesity
description From a Nutrology point of view, type 2 diabetes is a multi-factorial form of clinical “malnutrition” resulting from the intake of an imbalanced diet in combination with adverse environmental conditions and in the presence of predisposing genetic factors. In this review article, we present evidence of a close association between clinical obesity in a specific genetic background as the pillars of the process underlying the development of type 2 diabetes. We review the basics of the energy balance and the role of fat storage and body distribution in the pathogenesis of insulin resistance. We describe some molecular aspects of nutrients under normal physiology and during the metabolic and hormonal abnormalities that accompany type 2 diabetes. We conclude with a brief discussion of the principles behind popular dietary recommendations aimed at preventing the full development of diabetes mellitus and its complications.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39
10.1055/s-0040-1701422
url https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39
identifier_str_mv 10.1055/s-0040-1701422
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39/36
dc.rights.driver.fl_str_mv Copyright (c) 2022 International Journal of Nutrology
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 International Journal of Nutrology
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MetaScience Press
publisher.none.fl_str_mv MetaScience Press
dc.source.none.fl_str_mv International Journal of Nutrology; Vol. 5 No. 1 (2012): International Journal of Nutrology (IJN) - January 2012; 6-13
2595-2854
1984-3011
10.1055/s-010-45544
reponame:International Journal of Nutrology (Online)
instname:Associação Brasileira de Nutrologia (ABRAN)
instacron:ABRAN
instname_str Associação Brasileira de Nutrologia (ABRAN)
instacron_str ABRAN
institution ABRAN
reponame_str International Journal of Nutrology (Online)
collection International Journal of Nutrology (Online)
repository.name.fl_str_mv International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN)
repository.mail.fl_str_mv ijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com
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