Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | International Journal of Nutrology (Online) |
Texto Completo: | https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39 |
Resumo: | From a Nutrology point of view, type 2 diabetes is a multi-factorial form of clinical “malnutrition” resulting from the intake of an imbalanced diet in combination with adverse environmental conditions and in the presence of predisposing genetic factors. In this review article, we present evidence of a close association between clinical obesity in a specific genetic background as the pillars of the process underlying the development of type 2 diabetes. We review the basics of the energy balance and the role of fat storage and body distribution in the pathogenesis of insulin resistance. We describe some molecular aspects of nutrients under normal physiology and during the metabolic and hormonal abnormalities that accompany type 2 diabetes. We conclude with a brief discussion of the principles behind popular dietary recommendations aimed at preventing the full development of diabetes mellitus and its complications. |
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Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to diseaseType 2 DiabetesNutrient Patho-physiologyGenetics and ObesityFrom a Nutrology point of view, type 2 diabetes is a multi-factorial form of clinical “malnutrition” resulting from the intake of an imbalanced diet in combination with adverse environmental conditions and in the presence of predisposing genetic factors. In this review article, we present evidence of a close association between clinical obesity in a specific genetic background as the pillars of the process underlying the development of type 2 diabetes. We review the basics of the energy balance and the role of fat storage and body distribution in the pathogenesis of insulin resistance. We describe some molecular aspects of nutrients under normal physiology and during the metabolic and hormonal abnormalities that accompany type 2 diabetes. We conclude with a brief discussion of the principles behind popular dietary recommendations aimed at preventing the full development of diabetes mellitus and its complications.MetaScience Press2022-01-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articleapplication/pdfhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/3910.1055/s-0040-1701422International Journal of Nutrology; Vol. 5 No. 1 (2012): International Journal of Nutrology (IJN) - January 2012; 6-132595-28541984-301110.1055/s-010-45544reponame:International Journal of Nutrology (Online)instname:Associação Brasileira de Nutrologia (ABRAN)instacron:ABRANenghttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39/36Copyright (c) 2022 International Journal of Nutrologyinfo:eu-repo/semantics/openAccessCersosimo, EugenioOliveira, José Eduardo Dutra de2022-01-25T13:48:27Zoai:ojs2.ijn.zotarellifilhoscientificworks.com:article/39Revistahttps://ijn.zotarellifilhoscientificworks.com/index.php/ijnONGhttps://ijn.zotarellifilhoscientificworks.com/index.php/ijn/oaiijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com10.544482595-28541984-3011opendoar:2022-01-25T13:48:27International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN)false |
dc.title.none.fl_str_mv |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
title |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
spellingShingle |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease Cersosimo, Eugenio Type 2 Diabetes Nutrient Patho-physiology Genetics and Obesity |
title_short |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
title_full |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
title_fullStr |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
title_full_unstemmed |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
title_sort |
Nutrology and type 2 diabetes: Nutrient pathophysiology and the transition from health to disease |
author |
Cersosimo, Eugenio |
author_facet |
Cersosimo, Eugenio Oliveira, José Eduardo Dutra de |
author_role |
author |
author2 |
Oliveira, José Eduardo Dutra de |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Cersosimo, Eugenio Oliveira, José Eduardo Dutra de |
dc.subject.por.fl_str_mv |
Type 2 Diabetes Nutrient Patho-physiology Genetics and Obesity |
topic |
Type 2 Diabetes Nutrient Patho-physiology Genetics and Obesity |
description |
From a Nutrology point of view, type 2 diabetes is a multi-factorial form of clinical “malnutrition” resulting from the intake of an imbalanced diet in combination with adverse environmental conditions and in the presence of predisposing genetic factors. In this review article, we present evidence of a close association between clinical obesity in a specific genetic background as the pillars of the process underlying the development of type 2 diabetes. We review the basics of the energy balance and the role of fat storage and body distribution in the pathogenesis of insulin resistance. We describe some molecular aspects of nutrients under normal physiology and during the metabolic and hormonal abnormalities that accompany type 2 diabetes. We conclude with a brief discussion of the principles behind popular dietary recommendations aimed at preventing the full development of diabetes mellitus and its complications. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39 10.1055/s-0040-1701422 |
url |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39 |
identifier_str_mv |
10.1055/s-0040-1701422 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/39/36 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 International Journal of Nutrology info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 International Journal of Nutrology |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MetaScience Press |
publisher.none.fl_str_mv |
MetaScience Press |
dc.source.none.fl_str_mv |
International Journal of Nutrology; Vol. 5 No. 1 (2012): International Journal of Nutrology (IJN) - January 2012; 6-13 2595-2854 1984-3011 10.1055/s-010-45544 reponame:International Journal of Nutrology (Online) instname:Associação Brasileira de Nutrologia (ABRAN) instacron:ABRAN |
instname_str |
Associação Brasileira de Nutrologia (ABRAN) |
instacron_str |
ABRAN |
institution |
ABRAN |
reponame_str |
International Journal of Nutrology (Online) |
collection |
International Journal of Nutrology (Online) |
repository.name.fl_str_mv |
International Journal of Nutrology (Online) - Associação Brasileira de Nutrologia (ABRAN) |
repository.mail.fl_str_mv |
ijn@zotarellifilhoscientificworks.com || editorchief@zotarellifilhoscientificworks.com |
_version_ |
1792204587682234368 |