Are recurrent denture-related sores associated with the risk of oral cancer? A case control study
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista brasileira de epidemiologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2013000300705 |
Resumo: | Objectives: This study aimed to assess the hypothesis that recurrent denture-related sores association may be associated with the risk of oral cancer. Methods: We conducted a hospital-based case-control study comprising 71 new cases of oral cancer in two hospitals in São Paulo, Brazil, and 240 controls without cancer, recruited from outpatient units of the same hospitals. All cases had histologically confirmed squamous cell carcinoma in anatomic sites of the mouth that may be specifically consi-dered at risk of sores by ill-fitting dentures. Denture-related sores were assessed by the self-report of recurrent oral sores due to the use of ill-fitting complete removable dental prosthesis. Associations were assessed by multivariate logistic regression conditioned on socio-demographic and behavioral characteristics. Results: The association between ill-fitting dentures and oral cancer was statistically significant in the multivariate model: odds ratio 3.98; 95% confidence interval 1.06 - 14.96. The specific assessment of association between tumors in the lower jaw and sores by mandibular dentures confirmed this result: odds ratio 6.39; 95% confidence interval 1.49 - 29.52. Conclusion: The potential contribution of denture-related sores to oral carcinogenesis still fuels controversies. This study reinfor-ces the hypothesis that recurrent denture-related sores may be associated with the risk of oral cancer. Results reported here also suggest that an appropriate application and monitoring of dental prosthesis represent a non-negligible scope for cancer prevention. |
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Are recurrent denture-related sores associated with the risk of oral cancer? A case control studyEpidemiologyMouth neoplasmsDenturesCase-control studiesRisk factorsOral ulcer Objectives: This study aimed to assess the hypothesis that recurrent denture-related sores association may be associated with the risk of oral cancer. Methods: We conducted a hospital-based case-control study comprising 71 new cases of oral cancer in two hospitals in São Paulo, Brazil, and 240 controls without cancer, recruited from outpatient units of the same hospitals. All cases had histologically confirmed squamous cell carcinoma in anatomic sites of the mouth that may be specifically consi-dered at risk of sores by ill-fitting dentures. Denture-related sores were assessed by the self-report of recurrent oral sores due to the use of ill-fitting complete removable dental prosthesis. Associations were assessed by multivariate logistic regression conditioned on socio-demographic and behavioral characteristics. Results: The association between ill-fitting dentures and oral cancer was statistically significant in the multivariate model: odds ratio 3.98; 95% confidence interval 1.06 - 14.96. The specific assessment of association between tumors in the lower jaw and sores by mandibular dentures confirmed this result: odds ratio 6.39; 95% confidence interval 1.49 - 29.52. Conclusion: The potential contribution of denture-related sores to oral carcinogenesis still fuels controversies. This study reinfor-ces the hypothesis that recurrent denture-related sores may be associated with the risk of oral cancer. Results reported here also suggest that an appropriate application and monitoring of dental prosthesis represent a non-negligible scope for cancer prevention. Associação Brasileira de Saúde Coletiva2013-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2013000300705Revista Brasileira de Epidemiologia v.16 n.3 2013reponame:Revista brasileira de epidemiologia (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/S1415-790X2013000300014info:eu-repo/semantics/openAccessRotundo,Ligia Drovandi BragaToporcov,Tatiana NatashaBiazevic,Gabriela HayeCarvalho,Marcos Brasilino deKowalski,Luiz PauloAntunes,José Leopoldo Ferreiraeng2015-07-27T00:00:00Zoai:scielo:S1415-790X2013000300705Revistahttp://www.scielo.br/rbepidhttps://old.scielo.br/oai/scielo-oai.php||revbrepi@usp.br1980-54971415-790Xopendoar:2015-07-27T00:00Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false |
dc.title.none.fl_str_mv |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
title |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
spellingShingle |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study Rotundo,Ligia Drovandi Braga Epidemiology Mouth neoplasms Dentures Case-control studies Risk factors Oral ulcer |
title_short |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
title_full |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
title_fullStr |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
title_full_unstemmed |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
title_sort |
Are recurrent denture-related sores associated with the risk of oral cancer? A case control study |
author |
Rotundo,Ligia Drovandi Braga |
author_facet |
Rotundo,Ligia Drovandi Braga Toporcov,Tatiana Natasha Biazevic,Gabriela Haye Carvalho,Marcos Brasilino de Kowalski,Luiz Paulo Antunes,José Leopoldo Ferreira |
author_role |
author |
author2 |
Toporcov,Tatiana Natasha Biazevic,Gabriela Haye Carvalho,Marcos Brasilino de Kowalski,Luiz Paulo Antunes,José Leopoldo Ferreira |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Rotundo,Ligia Drovandi Braga Toporcov,Tatiana Natasha Biazevic,Gabriela Haye Carvalho,Marcos Brasilino de Kowalski,Luiz Paulo Antunes,José Leopoldo Ferreira |
dc.subject.por.fl_str_mv |
Epidemiology Mouth neoplasms Dentures Case-control studies Risk factors Oral ulcer |
topic |
Epidemiology Mouth neoplasms Dentures Case-control studies Risk factors Oral ulcer |
description |
Objectives: This study aimed to assess the hypothesis that recurrent denture-related sores association may be associated with the risk of oral cancer. Methods: We conducted a hospital-based case-control study comprising 71 new cases of oral cancer in two hospitals in São Paulo, Brazil, and 240 controls without cancer, recruited from outpatient units of the same hospitals. All cases had histologically confirmed squamous cell carcinoma in anatomic sites of the mouth that may be specifically consi-dered at risk of sores by ill-fitting dentures. Denture-related sores were assessed by the self-report of recurrent oral sores due to the use of ill-fitting complete removable dental prosthesis. Associations were assessed by multivariate logistic regression conditioned on socio-demographic and behavioral characteristics. Results: The association between ill-fitting dentures and oral cancer was statistically significant in the multivariate model: odds ratio 3.98; 95% confidence interval 1.06 - 14.96. The specific assessment of association between tumors in the lower jaw and sores by mandibular dentures confirmed this result: odds ratio 6.39; 95% confidence interval 1.49 - 29.52. Conclusion: The potential contribution of denture-related sores to oral carcinogenesis still fuels controversies. This study reinfor-ces the hypothesis that recurrent denture-related sores may be associated with the risk of oral cancer. Results reported here also suggest that an appropriate application and monitoring of dental prosthesis represent a non-negligible scope for cancer prevention. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2013000300705 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2013000300705 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1415-790X2013000300014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Saúde Coletiva |
publisher.none.fl_str_mv |
Associação Brasileira de Saúde Coletiva |
dc.source.none.fl_str_mv |
Revista Brasileira de Epidemiologia v.16 n.3 2013 reponame:Revista brasileira de epidemiologia (Online) instname:Associação Brasileira de Saúde Coletiva (ABRASCO) instacron:ABRASCO |
instname_str |
Associação Brasileira de Saúde Coletiva (ABRASCO) |
instacron_str |
ABRASCO |
institution |
ABRASCO |
reponame_str |
Revista brasileira de epidemiologia (Online) |
collection |
Revista brasileira de epidemiologia (Online) |
repository.name.fl_str_mv |
Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO) |
repository.mail.fl_str_mv |
||revbrepi@usp.br |
_version_ |
1754212953390841856 |