Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil

Detalhes bibliográficos
Autor(a) principal: Silva,Isabella Ribeiro
Data de Publicação: 2020
Outros Autores: Giatti,Luana, Chor,Dora, Fonseca,Maria de Jesus Mendes da, Mengue,Sotero Serrate, Acurcio,Francisco de Assis, Pereira,Mariana Linhares, Barreto,Sandhi Maria, Figueiredo,Roberta Carvalho de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista brasileira de epidemiologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2020000100465
Resumo: ABSTRACT: Objective: To estimate the prevalence of polypharmacy, describe the pharmacotherapeutic classes used, and investigate whether polypharmacy is associated with demographic and socioeconomic indicators, regardless of the number of diseases, among participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline (2008-2010). Method: In this analysis, 14,523 adults and elderly (35-74 years) participated. Polypharmacy was characterized as regular use of five or more medicines. The demographic and socioeconomic indicators analyzed were: gender, age, education level, per capita family income, and access to private health insurance. The independent association between demographic and economic indicators and polypharmacy was estimated by binary logistic regression. Results: The prevalence of polypharmacy was 11.7%. The most used drugs were those with action on the cardiovascular system. After adjustments, including by number of diseases, the chances of being on polypharmacy treatment were significantly higher among women, older participants and those with greatest number of diseases. Individuals without health insurance had lower chance to be under polypharmacy, as well as those with lower income. Conclusion: The occurrence of polypharmacy among ELSA-Brasil baseline participants was mainly due to drugs for the treatment of chronic diseases. The relation between polypharmacy and the female gender, as well as its association with old age, are in consonance with the results obtained in other studies. Despite the absence of an association between polypharmacy and education level, the income and health insurance results reinforce the existence of social inequalities regarding drug use.
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spelling Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-BrasilPharmacoepidemiologyPolypharmacyPopulation HealthDrug utilizationABSTRACT: Objective: To estimate the prevalence of polypharmacy, describe the pharmacotherapeutic classes used, and investigate whether polypharmacy is associated with demographic and socioeconomic indicators, regardless of the number of diseases, among participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline (2008-2010). Method: In this analysis, 14,523 adults and elderly (35-74 years) participated. Polypharmacy was characterized as regular use of five or more medicines. The demographic and socioeconomic indicators analyzed were: gender, age, education level, per capita family income, and access to private health insurance. The independent association between demographic and economic indicators and polypharmacy was estimated by binary logistic regression. Results: The prevalence of polypharmacy was 11.7%. The most used drugs were those with action on the cardiovascular system. After adjustments, including by number of diseases, the chances of being on polypharmacy treatment were significantly higher among women, older participants and those with greatest number of diseases. Individuals without health insurance had lower chance to be under polypharmacy, as well as those with lower income. Conclusion: The occurrence of polypharmacy among ELSA-Brasil baseline participants was mainly due to drugs for the treatment of chronic diseases. The relation between polypharmacy and the female gender, as well as its association with old age, are in consonance with the results obtained in other studies. Despite the absence of an association between polypharmacy and education level, the income and health insurance results reinforce the existence of social inequalities regarding drug use.Associação Brasileira de Saúde Coletiva2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-790X2020000100465Revista Brasileira de Epidemiologia v.23 2020reponame:Revista brasileira de epidemiologia (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/1980-549720200077info:eu-repo/semantics/openAccessSilva,Isabella RibeiroGiatti,LuanaChor,DoraFonseca,Maria de Jesus Mendes daMengue,Sotero SerrateAcurcio,Francisco de AssisPereira,Mariana LinharesBarreto,Sandhi MariaFigueiredo,Roberta Carvalho deeng2020-08-14T00:00:00Zoai:scielo:S1415-790X2020000100465Revistahttp://www.scielo.br/rbepidhttps://old.scielo.br/oai/scielo-oai.php||revbrepi@usp.br1980-54971415-790Xopendoar:2020-08-14T00:00Revista brasileira de epidemiologia (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false
dc.title.none.fl_str_mv Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
title Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
spellingShingle Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
Silva,Isabella Ribeiro
Pharmacoepidemiology
Polypharmacy
Population Health
Drug utilization
title_short Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
title_full Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
title_fullStr Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
title_full_unstemmed Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
title_sort Polypharmacy, socioeconomic indicators and number of diseases: results from ELSA-Brasil
author Silva,Isabella Ribeiro
author_facet Silva,Isabella Ribeiro
Giatti,Luana
Chor,Dora
Fonseca,Maria de Jesus Mendes da
Mengue,Sotero Serrate
Acurcio,Francisco de Assis
Pereira,Mariana Linhares
Barreto,Sandhi Maria
Figueiredo,Roberta Carvalho de
author_role author
author2 Giatti,Luana
Chor,Dora
Fonseca,Maria de Jesus Mendes da
Mengue,Sotero Serrate
Acurcio,Francisco de Assis
Pereira,Mariana Linhares
Barreto,Sandhi Maria
Figueiredo,Roberta Carvalho de
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,Isabella Ribeiro
Giatti,Luana
Chor,Dora
Fonseca,Maria de Jesus Mendes da
Mengue,Sotero Serrate
Acurcio,Francisco de Assis
Pereira,Mariana Linhares
Barreto,Sandhi Maria
Figueiredo,Roberta Carvalho de
dc.subject.por.fl_str_mv Pharmacoepidemiology
Polypharmacy
Population Health
Drug utilization
topic Pharmacoepidemiology
Polypharmacy
Population Health
Drug utilization
description ABSTRACT: Objective: To estimate the prevalence of polypharmacy, describe the pharmacotherapeutic classes used, and investigate whether polypharmacy is associated with demographic and socioeconomic indicators, regardless of the number of diseases, among participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline (2008-2010). Method: In this analysis, 14,523 adults and elderly (35-74 years) participated. Polypharmacy was characterized as regular use of five or more medicines. The demographic and socioeconomic indicators analyzed were: gender, age, education level, per capita family income, and access to private health insurance. The independent association between demographic and economic indicators and polypharmacy was estimated by binary logistic regression. Results: The prevalence of polypharmacy was 11.7%. The most used drugs were those with action on the cardiovascular system. After adjustments, including by number of diseases, the chances of being on polypharmacy treatment were significantly higher among women, older participants and those with greatest number of diseases. Individuals without health insurance had lower chance to be under polypharmacy, as well as those with lower income. Conclusion: The occurrence of polypharmacy among ELSA-Brasil baseline participants was mainly due to drugs for the treatment of chronic diseases. The relation between polypharmacy and the female gender, as well as its association with old age, are in consonance with the results obtained in other studies. Despite the absence of an association between polypharmacy and education level, the income and health insurance results reinforce the existence of social inequalities regarding drug use.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01
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dc.publisher.none.fl_str_mv Associação Brasileira de Saúde Coletiva
publisher.none.fl_str_mv Associação Brasileira de Saúde Coletiva
dc.source.none.fl_str_mv Revista Brasileira de Epidemiologia v.23 2020
reponame:Revista brasileira de epidemiologia (Online)
instname:Associação Brasileira de Saúde Coletiva (ABRASCO)
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