Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência & Saúde Coletiva (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232016001103499 |
Resumo: | Abstract Exposure to high levels of cortisol and self-reported stress, as well as cognitive reserve, have been linked to Alzheimer’s disease pathology. However, there are no studies on the interaction of these variables. The present study aims to assess the associations of measures of cortisol, self-reported stress, and cognitive reserve with neuropsychological performance in healthy elderly people; besides, to test the interactions between these variables. Cross-sectional analyzes were conducted using data on stress, cognitive reserve and clinical conditions in 145 healthy elderly adults. A neuropsychological battery was used to assess executive functions, verbal memory and processing speed. Measurement of salivary cortisol at the circadian nadir was taken. A negative association between different stress measures and performance on tasks of memory, executive functions and processing speed was observed. Elderly people with higher cognitive reserve showed superior performance on all neuropsychological measures. No significant interaction between stress and cognitive reserve to neuropsychological performance was observed. These results indicate that older adults with high levels of stress and reduced cognitive reserve may be more susceptible to cognitive impairment. |
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Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderlySalivary cortisolGlucocorticoidStressCognitive reserveAbstract Exposure to high levels of cortisol and self-reported stress, as well as cognitive reserve, have been linked to Alzheimer’s disease pathology. However, there are no studies on the interaction of these variables. The present study aims to assess the associations of measures of cortisol, self-reported stress, and cognitive reserve with neuropsychological performance in healthy elderly people; besides, to test the interactions between these variables. Cross-sectional analyzes were conducted using data on stress, cognitive reserve and clinical conditions in 145 healthy elderly adults. A neuropsychological battery was used to assess executive functions, verbal memory and processing speed. Measurement of salivary cortisol at the circadian nadir was taken. A negative association between different stress measures and performance on tasks of memory, executive functions and processing speed was observed. Elderly people with higher cognitive reserve showed superior performance on all neuropsychological measures. No significant interaction between stress and cognitive reserve to neuropsychological performance was observed. These results indicate that older adults with high levels of stress and reduced cognitive reserve may be more susceptible to cognitive impairment.ABRASCO - Associação Brasileira de Saúde Coletiva2016-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232016001103499Ciência & Saúde Coletiva v.21 n.11 2016reponame:Ciência & Saúde Coletiva (Online)instname:Associação Brasileira de Saúde Coletiva (ABRASCO)instacron:ABRASCO10.1590/1413-812320152111.17452015info:eu-repo/semantics/openAccessCabral,João Carlos CenturionVeleda,Gessyka WanglonMazzoleni,MartinaColares,Elton PintoNeiva-Silva,LucasNeves,Vera Torres daseng2016-11-04T00:00:00Zoai:scielo:S1413-81232016001103499Revistahttp://www.cienciaesaudecoletiva.com.brhttps://old.scielo.br/oai/scielo-oai.php||cienciasaudecoletiva@fiocruz.br1678-45611413-8123opendoar:2016-11-04T00:00Ciência & Saúde Coletiva (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO)false |
dc.title.none.fl_str_mv |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
title |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
spellingShingle |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly Cabral,João Carlos Centurion Salivary cortisol Glucocorticoid Stress Cognitive reserve |
title_short |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
title_full |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
title_fullStr |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
title_full_unstemmed |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
title_sort |
Stress and Cognitive Reserve as independent factors of neuropsychological performance in healthy elderly |
author |
Cabral,João Carlos Centurion |
author_facet |
Cabral,João Carlos Centurion Veleda,Gessyka Wanglon Mazzoleni,Martina Colares,Elton Pinto Neiva-Silva,Lucas Neves,Vera Torres das |
author_role |
author |
author2 |
Veleda,Gessyka Wanglon Mazzoleni,Martina Colares,Elton Pinto Neiva-Silva,Lucas Neves,Vera Torres das |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Cabral,João Carlos Centurion Veleda,Gessyka Wanglon Mazzoleni,Martina Colares,Elton Pinto Neiva-Silva,Lucas Neves,Vera Torres das |
dc.subject.por.fl_str_mv |
Salivary cortisol Glucocorticoid Stress Cognitive reserve |
topic |
Salivary cortisol Glucocorticoid Stress Cognitive reserve |
description |
Abstract Exposure to high levels of cortisol and self-reported stress, as well as cognitive reserve, have been linked to Alzheimer’s disease pathology. However, there are no studies on the interaction of these variables. The present study aims to assess the associations of measures of cortisol, self-reported stress, and cognitive reserve with neuropsychological performance in healthy elderly people; besides, to test the interactions between these variables. Cross-sectional analyzes were conducted using data on stress, cognitive reserve and clinical conditions in 145 healthy elderly adults. A neuropsychological battery was used to assess executive functions, verbal memory and processing speed. Measurement of salivary cortisol at the circadian nadir was taken. A negative association between different stress measures and performance on tasks of memory, executive functions and processing speed was observed. Elderly people with higher cognitive reserve showed superior performance on all neuropsychological measures. No significant interaction between stress and cognitive reserve to neuropsychological performance was observed. These results indicate that older adults with high levels of stress and reduced cognitive reserve may be more susceptible to cognitive impairment. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232016001103499 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-81232016001103499 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1413-812320152111.17452015 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
ABRASCO - Associação Brasileira de Saúde Coletiva |
publisher.none.fl_str_mv |
ABRASCO - Associação Brasileira de Saúde Coletiva |
dc.source.none.fl_str_mv |
Ciência & Saúde Coletiva v.21 n.11 2016 reponame:Ciência & Saúde Coletiva (Online) instname:Associação Brasileira de Saúde Coletiva (ABRASCO) instacron:ABRASCO |
instname_str |
Associação Brasileira de Saúde Coletiva (ABRASCO) |
instacron_str |
ABRASCO |
institution |
ABRASCO |
reponame_str |
Ciência & Saúde Coletiva (Online) |
collection |
Ciência & Saúde Coletiva (Online) |
repository.name.fl_str_mv |
Ciência & Saúde Coletiva (Online) - Associação Brasileira de Saúde Coletiva (ABRASCO) |
repository.mail.fl_str_mv |
||cienciasaudecoletiva@fiocruz.br |
_version_ |
1754213039680258048 |