Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes

Detalhes bibliográficos
Autor(a) principal: Martins,Eduardo Bello
Data de Publicação: 2020
Outros Autores: Lima,Eduardo Gomes, Pitta,Fábio Grunspun, Carvalho,Leticia Neves Solon, Queiroz,Thiago Dias de, Serrano Júnior,Carlos Vicente
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Associação Médica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000901283
Resumo: SUMMARY The pharmacological therapy for type 2 diabetes mellitus has presented important advances in recent years, which has impacted the treatment of patients with established cardiovascular disease or with high cardiovascular risk. In this scenario, two drug classes have emerged and demonstrated clear clinical benefits: SGLT-2 inhibitors and GLP-1 agonists. The present review discusses the pharmacology, adverse effects, and clinical trials that have demonstrated the benefits of these medications in reducing cardiovascular risk.
id AMB-1_171382cad017d49de05e525f5b542b2a
oai_identifier_str oai:scielo:S0104-42302020000901283
network_acronym_str AMB-1
network_name_str Revista da Associação Médica Brasileira (Online)
repository_id_str
spelling Pharmacological therapy and cardiovascular risk reduction for type 2 diabetesDiabetes mellitusHypoglycemic agentsHeart diseaseSUMMARY The pharmacological therapy for type 2 diabetes mellitus has presented important advances in recent years, which has impacted the treatment of patients with established cardiovascular disease or with high cardiovascular risk. In this scenario, two drug classes have emerged and demonstrated clear clinical benefits: SGLT-2 inhibitors and GLP-1 agonists. The present review discusses the pharmacology, adverse effects, and clinical trials that have demonstrated the benefits of these medications in reducing cardiovascular risk.Associação Médica Brasileira2020-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000901283Revista da Associação Médica Brasileira v.66 n.9 2020reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.66.9.1283info:eu-repo/semantics/openAccessMartins,Eduardo BelloLima,Eduardo GomesPitta,Fábio GrunspunCarvalho,Leticia Neves SolonQueiroz,Thiago Dias deSerrano Júnior,Carlos Vicenteeng2020-11-04T00:00:00Zoai:scielo:S0104-42302020000901283Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2020-11-04T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false
dc.title.none.fl_str_mv Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
title Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
spellingShingle Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
Martins,Eduardo Bello
Diabetes mellitus
Hypoglycemic agents
Heart disease
title_short Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
title_full Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
title_fullStr Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
title_full_unstemmed Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
title_sort Pharmacological therapy and cardiovascular risk reduction for type 2 diabetes
author Martins,Eduardo Bello
author_facet Martins,Eduardo Bello
Lima,Eduardo Gomes
Pitta,Fábio Grunspun
Carvalho,Leticia Neves Solon
Queiroz,Thiago Dias de
Serrano Júnior,Carlos Vicente
author_role author
author2 Lima,Eduardo Gomes
Pitta,Fábio Grunspun
Carvalho,Leticia Neves Solon
Queiroz,Thiago Dias de
Serrano Júnior,Carlos Vicente
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Martins,Eduardo Bello
Lima,Eduardo Gomes
Pitta,Fábio Grunspun
Carvalho,Leticia Neves Solon
Queiroz,Thiago Dias de
Serrano Júnior,Carlos Vicente
dc.subject.por.fl_str_mv Diabetes mellitus
Hypoglycemic agents
Heart disease
topic Diabetes mellitus
Hypoglycemic agents
Heart disease
description SUMMARY The pharmacological therapy for type 2 diabetes mellitus has presented important advances in recent years, which has impacted the treatment of patients with established cardiovascular disease or with high cardiovascular risk. In this scenario, two drug classes have emerged and demonstrated clear clinical benefits: SGLT-2 inhibitors and GLP-1 agonists. The present review discusses the pharmacology, adverse effects, and clinical trials that have demonstrated the benefits of these medications in reducing cardiovascular risk.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000901283
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000901283
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9282.66.9.1283
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira v.66 n.9 2020
reponame:Revista da Associação Médica Brasileira (Online)
instname:Associação Médica Brasileira (AMB)
instacron:AMB
instname_str Associação Médica Brasileira (AMB)
instacron_str AMB
institution AMB
reponame_str Revista da Associação Médica Brasileira (Online)
collection Revista da Associação Médica Brasileira (Online)
repository.name.fl_str_mv Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)
repository.mail.fl_str_mv ||ramb@amb.org.br
_version_ 1754212835259318272

Registros relacionados