Risk of venous thromboembolism in users of contraception and menopausal hormone therapy during the COVID-19 pandemic

• Autor(a) principal: Pires,Andréa Larissa Ribeiro
• Data de Publicação: 2020
• Outros Autores: Batista,José Gomes, Aldrighi,José Mendes, Massaia,Irineu Francisco Delfino Silva, Delgado,Diego Medeiros, Ferreira-Filho,Edson Santos, Soares-Junior,José Maria
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Associação Médica Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020001400022
• topic: Contraception; Hormone Replacement Therapy; Coronavirus Infections; Betacoronavirus; Venous Thromboembolism/prevention & control

SUMMARY OBJECTIVES The outbreak of coronavirus disease (COVID-19) is a public health emergency of international concern. Inflammatory changes are part of COVID-19 pathophysiology and this might generate a higher thromboembolic risk in patients using combined hormonal contraception and menopausal hormone therapy. We aimed to discuss the main aspects related to this issue and propose management strategies for women affected by COVID-19. METHODS This narrative review collected information from several articles published since the beginning of the outbreak of the new coronavirus disease about the pathophysiology, stage of the disease, the occurrence of thrombotic events, and the risk of thromboembolism in users of contraception and hormonal therapy. RESULTS This article consolidates clinical parameters about the risk of venous thromboembolism in users of contraception and menopausal hormone therapy emphasizing the probable increase of that risk in women with suspected or confirmed COVID-19 and bringing safer recommendations. CONCLUSIONS In this scenario, apart from the fundamental orientations of preventive measures, like social isolation and hygiene, it is important that all female health professionals have knowledge of the new rules and adopt safety measures, especially on the prescription of hormonal therapy and contraception.