Wernicke's encephalopathy in a patient with non-Hodgkin's lymphoma post-Autologous HSCT

• Autor(a) principal: Leitão,João Paulo de Vasconcelos
• Data de Publicação: 2018
• Outros Autores: Lemes,Romélia Pinheiro Gonçalves, Barbosa,Maritza Cavalcante, Araújo,Beatriz Stela Gomes de Souza Pitombeira, Barroso,Karine Sampaio Nunes, Kaufman,Jacques, Santos,Talyta Ellen de Jesus dos, Moura,Anna Thawanny Gadelha, Barreto,André Rodrigues Façanha, Duarte,Fernando Barroso
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Associação Médica Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302018001000882
• topic: Wernicke's encephalopathy; non-hodgkin's lymphoma; autologous hsct; thiamine deficiency

SUMMARY Wernick's Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predisposed the occurrence of WE in a patient with non-Hodgkin's lymphoma post-Autologous HSCT. We conclude that WE should be considered in patients submitted to autologous HSCT associated with prolonged use of TPN and malnutrition.