Seroepidemiologic survey of the household contacts of leprosy patients

Detalhes bibliográficos
Autor(a) principal: Barbosa,Angela Marques
Data de Publicação: 2022
Outros Autores: Silva,Suelen Umbelino da, Toledo,Ana Clara Campagnolo Gonçalves, Abreu,Marilda Aparecida Milanez Morgado de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Associação Médica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302022001001389
Resumo: SUMMARY OBJECTIVE: Leprosy is a disabling infectious disease caused by Mycobacterium leprae. This study aimed to investigate the prevalence of leprosy among household contacts of leprosy patients. METHODS: This study is a serological survey in household contacts of leprosy patients who had been treated or were undergoing treatment in the city of Presidente Prudente, São Paulo, Brazil, from 2006–2016, using clinical examination and screening for anti- Phenolic glycolipid-I antibodies with Mycobacterium leprae-flow serology. RESULTS: A total of 263 index cases of leprosy were identified during the study period. Of these, 53 were approached, and among their household contacts, 108 were examined. The ML-flow test was positive in 2 (1.85%) individuals, but clinical examination revealed no signs or symptoms of leprosy in them. Therefore, they were considered to have a subclinical infection. Leprosy was not confirmed in any household contacts. In this study, a lower percentage of household contacts, when compared to that in the literature, had a positive Mycobacterium leprae-flow test result. CONCLUSION: The use of Mycobacterium leprae-flow should be encouraged during the follow-up of at-risk populations, such as the household contacts of leprosy patients.
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spelling Seroepidemiologic survey of the household contacts of leprosy patientsHansen's diseaseLeprosyMycobacterium lepraeSerologic testsSUMMARY OBJECTIVE: Leprosy is a disabling infectious disease caused by Mycobacterium leprae. This study aimed to investigate the prevalence of leprosy among household contacts of leprosy patients. METHODS: This study is a serological survey in household contacts of leprosy patients who had been treated or were undergoing treatment in the city of Presidente Prudente, São Paulo, Brazil, from 2006–2016, using clinical examination and screening for anti- Phenolic glycolipid-I antibodies with Mycobacterium leprae-flow serology. RESULTS: A total of 263 index cases of leprosy were identified during the study period. Of these, 53 were approached, and among their household contacts, 108 were examined. The ML-flow test was positive in 2 (1.85%) individuals, but clinical examination revealed no signs or symptoms of leprosy in them. Therefore, they were considered to have a subclinical infection. Leprosy was not confirmed in any household contacts. In this study, a lower percentage of household contacts, when compared to that in the literature, had a positive Mycobacterium leprae-flow test result. CONCLUSION: The use of Mycobacterium leprae-flow should be encouraged during the follow-up of at-risk populations, such as the household contacts of leprosy patients.Associação Médica Brasileira2022-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302022001001389Revista da Associação Médica Brasileira v.68 n.10 2022reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.20220248info:eu-repo/semantics/openAccessBarbosa,Angela MarquesSilva,Suelen Umbelino daToledo,Ana Clara Campagnolo GonçalvesAbreu,Marilda Aparecida Milanez Morgado deeng2022-11-11T00:00:00Zoai:scielo:S0104-42302022001001389Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2022-11-11T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false
dc.title.none.fl_str_mv Seroepidemiologic survey of the household contacts of leprosy patients
title Seroepidemiologic survey of the household contacts of leprosy patients
spellingShingle Seroepidemiologic survey of the household contacts of leprosy patients
Barbosa,Angela Marques
Hansen's disease
Leprosy
Mycobacterium leprae
Serologic tests
title_short Seroepidemiologic survey of the household contacts of leprosy patients
title_full Seroepidemiologic survey of the household contacts of leprosy patients
title_fullStr Seroepidemiologic survey of the household contacts of leprosy patients
title_full_unstemmed Seroepidemiologic survey of the household contacts of leprosy patients
title_sort Seroepidemiologic survey of the household contacts of leprosy patients
author Barbosa,Angela Marques
author_facet Barbosa,Angela Marques
Silva,Suelen Umbelino da
Toledo,Ana Clara Campagnolo Gonçalves
Abreu,Marilda Aparecida Milanez Morgado de
author_role author
author2 Silva,Suelen Umbelino da
Toledo,Ana Clara Campagnolo Gonçalves
Abreu,Marilda Aparecida Milanez Morgado de
author2_role author
author
author
dc.contributor.author.fl_str_mv Barbosa,Angela Marques
Silva,Suelen Umbelino da
Toledo,Ana Clara Campagnolo Gonçalves
Abreu,Marilda Aparecida Milanez Morgado de
dc.subject.por.fl_str_mv Hansen's disease
Leprosy
Mycobacterium leprae
Serologic tests
topic Hansen's disease
Leprosy
Mycobacterium leprae
Serologic tests
description SUMMARY OBJECTIVE: Leprosy is a disabling infectious disease caused by Mycobacterium leprae. This study aimed to investigate the prevalence of leprosy among household contacts of leprosy patients. METHODS: This study is a serological survey in household contacts of leprosy patients who had been treated or were undergoing treatment in the city of Presidente Prudente, São Paulo, Brazil, from 2006–2016, using clinical examination and screening for anti- Phenolic glycolipid-I antibodies with Mycobacterium leprae-flow serology. RESULTS: A total of 263 index cases of leprosy were identified during the study period. Of these, 53 were approached, and among their household contacts, 108 were examined. The ML-flow test was positive in 2 (1.85%) individuals, but clinical examination revealed no signs or symptoms of leprosy in them. Therefore, they were considered to have a subclinical infection. Leprosy was not confirmed in any household contacts. In this study, a lower percentage of household contacts, when compared to that in the literature, had a positive Mycobacterium leprae-flow test result. CONCLUSION: The use of Mycobacterium leprae-flow should be encouraged during the follow-up of at-risk populations, such as the household contacts of leprosy patients.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9282.20220248
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dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira v.68 n.10 2022
reponame:Revista da Associação Médica Brasileira (Online)
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