Estrogen signaling in the proliferative endometrium: implications in endometriosis
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Associação Médica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000100072 |
Resumo: | SUMMARY Even though the physiological role of estrogen in the female reproductive cycle and endometrial proliferative phase is well established, the signaling pathways by which estrogen exerts its action in the endometrial tissue are still little known. In this regard, advancements in cell culture techniques and maintenance of endometrial cells in cultures enabled the discovery of new signaling mechanisms activated by estrogen in the normal endometrium and in endometriosis. This review aims to present the recent findings in the genomic and non-genomic estrogen signaling pathways in the proliferative human endometrium specifically associated with the pathogenesis and development of endometriosis. |
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Estrogen signaling in the proliferative endometrium: implications in endometriosisendometriumestrogenssignal transductionendometriosisSUMMARY Even though the physiological role of estrogen in the female reproductive cycle and endometrial proliferative phase is well established, the signaling pathways by which estrogen exerts its action in the endometrial tissue are still little known. In this regard, advancements in cell culture techniques and maintenance of endometrial cells in cultures enabled the discovery of new signaling mechanisms activated by estrogen in the normal endometrium and in endometriosis. This review aims to present the recent findings in the genomic and non-genomic estrogen signaling pathways in the proliferative human endometrium specifically associated with the pathogenesis and development of endometriosis.Associação Médica Brasileira2016-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000100072Revista da Associação Médica Brasileira v.62 n.1 2016reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.62.01.72info:eu-repo/semantics/openAccessSilva,Rita de Cássia Pereira da Costa eMoura,Kátia Karina Verolli de OliveiraRibeiro Júnior,Circoncisto LaurentinoGuillo,Lidia Andreueng2016-03-18T00:00:00Zoai:scielo:S0104-42302016000100072Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2016-03-18T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false |
dc.title.none.fl_str_mv |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
title |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
spellingShingle |
Estrogen signaling in the proliferative endometrium: implications in endometriosis Silva,Rita de Cássia Pereira da Costa e endometrium estrogens signal transduction endometriosis |
title_short |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
title_full |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
title_fullStr |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
title_full_unstemmed |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
title_sort |
Estrogen signaling in the proliferative endometrium: implications in endometriosis |
author |
Silva,Rita de Cássia Pereira da Costa e |
author_facet |
Silva,Rita de Cássia Pereira da Costa e Moura,Kátia Karina Verolli de Oliveira Ribeiro Júnior,Circoncisto Laurentino Guillo,Lidia Andreu |
author_role |
author |
author2 |
Moura,Kátia Karina Verolli de Oliveira Ribeiro Júnior,Circoncisto Laurentino Guillo,Lidia Andreu |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silva,Rita de Cássia Pereira da Costa e Moura,Kátia Karina Verolli de Oliveira Ribeiro Júnior,Circoncisto Laurentino Guillo,Lidia Andreu |
dc.subject.por.fl_str_mv |
endometrium estrogens signal transduction endometriosis |
topic |
endometrium estrogens signal transduction endometriosis |
description |
SUMMARY Even though the physiological role of estrogen in the female reproductive cycle and endometrial proliferative phase is well established, the signaling pathways by which estrogen exerts its action in the endometrial tissue are still little known. In this regard, advancements in cell culture techniques and maintenance of endometrial cells in cultures enabled the discovery of new signaling mechanisms activated by estrogen in the normal endometrium and in endometriosis. This review aims to present the recent findings in the genomic and non-genomic estrogen signaling pathways in the proliferative human endometrium specifically associated with the pathogenesis and development of endometriosis. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000100072 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000100072 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1806-9282.62.01.72 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Médica Brasileira |
publisher.none.fl_str_mv |
Associação Médica Brasileira |
dc.source.none.fl_str_mv |
Revista da Associação Médica Brasileira v.62 n.1 2016 reponame:Revista da Associação Médica Brasileira (Online) instname:Associação Médica Brasileira (AMB) instacron:AMB |
instname_str |
Associação Médica Brasileira (AMB) |
instacron_str |
AMB |
institution |
AMB |
reponame_str |
Revista da Associação Médica Brasileira (Online) |
collection |
Revista da Associação Médica Brasileira (Online) |
repository.name.fl_str_mv |
Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB) |
repository.mail.fl_str_mv |
||ramb@amb.org.br |
_version_ |
1754212831624953856 |