Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury

Detalhes bibliográficos
Autor(a) principal: Celepli,Salih
Data de Publicação: 2022
Outros Autores: Çolak,Bayram, Celepli,Pınar, Bigat,İrem, Batur,Hatice Gül, Soysal,Furkan, Karakurt,Serdar, Hücümenoğlu,Sema, Kısmet,Kemal, Ԟahin,Mustafa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Associação Médica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302022000100087
Resumo: SUMMARY OBJECTIVE: The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury. METHODS: Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively. RESULTS: Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher. CONCLUSIONS: As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and anti-inflammatory effects of artichoke.
id AMB-1_b5e4a49c86277b20f7cb822b8f81034e
oai_identifier_str oai:scielo:S0104-42302022000100087
network_acronym_str AMB-1
network_name_str Revista da Associação Médica Brasileira (Online)
repository_id_str
spelling Effects of artichoke leaf extract on hepatic ischemia-reperfusion injuryLiverIschemia-reperfusionArtichokeHepatoprotectiveAntioxidantSUMMARY OBJECTIVE: The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury. METHODS: Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively. RESULTS: Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher. CONCLUSIONS: As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and anti-inflammatory effects of artichoke.Associação Médica Brasileira2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302022000100087Revista da Associação Médica Brasileira v.68 n.1 2022reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.20210840info:eu-repo/semantics/openAccessCelepli,SalihÇolak,BayramCelepli,PınarBigat,İremBatur,Hatice GülSoysal,FurkanKarakurt,SerdarHücümenoğlu,SemaKısmet,KemalԞahin,Mustafaeng2022-08-26T00:00:00Zoai:scielo:S0104-42302022000100087Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2022-08-26T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false
dc.title.none.fl_str_mv Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
title Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
spellingShingle Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
Celepli,Salih
Liver
Ischemia-reperfusion
Artichoke
Hepatoprotective
Antioxidant
title_short Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
title_full Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
title_fullStr Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
title_full_unstemmed Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
title_sort Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury
author Celepli,Salih
author_facet Celepli,Salih
Çolak,Bayram
Celepli,Pınar
Bigat,İrem
Batur,Hatice Gül
Soysal,Furkan
Karakurt,Serdar
Hücümenoğlu,Sema
Kısmet,Kemal
Ԟahin,Mustafa
author_role author
author2 Çolak,Bayram
Celepli,Pınar
Bigat,İrem
Batur,Hatice Gül
Soysal,Furkan
Karakurt,Serdar
Hücümenoğlu,Sema
Kısmet,Kemal
Ԟahin,Mustafa
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Celepli,Salih
Çolak,Bayram
Celepli,Pınar
Bigat,İrem
Batur,Hatice Gül
Soysal,Furkan
Karakurt,Serdar
Hücümenoğlu,Sema
Kısmet,Kemal
Ԟahin,Mustafa
dc.subject.por.fl_str_mv Liver
Ischemia-reperfusion
Artichoke
Hepatoprotective
Antioxidant
topic Liver
Ischemia-reperfusion
Artichoke
Hepatoprotective
Antioxidant
description SUMMARY OBJECTIVE: The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury. METHODS: Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively. RESULTS: Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher. CONCLUSIONS: As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and anti-inflammatory effects of artichoke.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302022000100087
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302022000100087
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9282.20210840
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira v.68 n.1 2022
reponame:Revista da Associação Médica Brasileira (Online)
instname:Associação Médica Brasileira (AMB)
instacron:AMB
instname_str Associação Médica Brasileira (AMB)
instacron_str AMB
institution AMB
reponame_str Revista da Associação Médica Brasileira (Online)
collection Revista da Associação Médica Brasileira (Online)
repository.name.fl_str_mv Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)
repository.mail.fl_str_mv ||ramb@amb.org.br
_version_ 1754212837310332928

Registros relacionados