Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application

Detalhes bibliográficos
Autor(a) principal: Moraes,Fabio Ynoe
Data de Publicação: 2016
Outros Autores: Bonifacio,Lorine Arias, Neves-Junior,Wellington Pimenta, Hanna,Samir Abdallah, Abreu,Carlos Eduardo Cintra Vita, Arruda,Fernando Freire, Silva,João Luis Fernandes, Carvalho,Heloisa Andrade
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Associação Médica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000800782
Resumo: Summary Objective: To provide a quantitative profile of the indications and use of stereotactic body radiotherapy (SBRT) in a developing country oncology-based institution. In addition, to describe the patients' and treatment characteristics, and to provide a temporal analysis. Method: SBRT patients treated from 2007 to 2015 were retrospectively evaluated by two independently investigators. Data were stratified and compared in two periods: first experience (FE) (May 2007 to April 2011), and following experience (FollowE) (May 2011 to April 2015). The following parameters were compared between the groups: total number of treated patients and lesions, treatment site, additional image fusion used, formal protocol adoption, and SBRT planning technique. Results: One hundred and seventy-six (176) patients with 191 lesions were treated: 34 (18%) lesions in the FE and 157 (82%) lesions in FollowE. The majority of lesions were metastases (60.3%), and lung (60.2%) was the most common treatment site, followed by spine (31%), and others (8.8%). An average of 1.4 (±0.6) additional imaging exams for delineation was performed. Conformal 3D radiotherapy planning technique was used in 64.4%, and intensity modulated radiotherapy (IMRT) or volumetric-modulated arc therapy (VMAT) in the remaining 35.6% (p=0.0001). Higher rates of curative treatments were observed in FE, as well as more lung lesions, patients ≥ 70 years, 3D conformal, number of additional images and ECOG 0, and all presented p<0.05. The global rate of protocol statement was 79%, lung treatment being the most stated. Conclusion: SBRT application is rapidly increasing in our setting. Treatment sites and planning techniques are becoming more diversified and complex.
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spelling Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy applicationstereotactic body radiotherapyradiation oncologylung neoplasmradiosurgerySummary Objective: To provide a quantitative profile of the indications and use of stereotactic body radiotherapy (SBRT) in a developing country oncology-based institution. In addition, to describe the patients' and treatment characteristics, and to provide a temporal analysis. Method: SBRT patients treated from 2007 to 2015 were retrospectively evaluated by two independently investigators. Data were stratified and compared in two periods: first experience (FE) (May 2007 to April 2011), and following experience (FollowE) (May 2011 to April 2015). The following parameters were compared between the groups: total number of treated patients and lesions, treatment site, additional image fusion used, formal protocol adoption, and SBRT planning technique. Results: One hundred and seventy-six (176) patients with 191 lesions were treated: 34 (18%) lesions in the FE and 157 (82%) lesions in FollowE. The majority of lesions were metastases (60.3%), and lung (60.2%) was the most common treatment site, followed by spine (31%), and others (8.8%). An average of 1.4 (±0.6) additional imaging exams for delineation was performed. Conformal 3D radiotherapy planning technique was used in 64.4%, and intensity modulated radiotherapy (IMRT) or volumetric-modulated arc therapy (VMAT) in the remaining 35.6% (p=0.0001). Higher rates of curative treatments were observed in FE, as well as more lung lesions, patients ≥ 70 years, 3D conformal, number of additional images and ECOG 0, and all presented p<0.05. The global rate of protocol statement was 79%, lung treatment being the most stated. Conclusion: SBRT application is rapidly increasing in our setting. Treatment sites and planning techniques are becoming more diversified and complex.Associação Médica Brasileira2016-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302016000800782Revista da Associação Médica Brasileira v.62 n.8 2016reponame:Revista da Associação Médica Brasileira (Online)instname:Associação Médica Brasileira (AMB)instacron:AMB10.1590/1806-9282.62.08.782info:eu-repo/semantics/openAccessMoraes,Fabio YnoeBonifacio,Lorine AriasNeves-Junior,Wellington PimentaHanna,Samir AbdallahAbreu,Carlos Eduardo Cintra VitaArruda,Fernando FreireSilva,João Luis FernandesCarvalho,Heloisa Andradeeng2016-12-15T00:00:00Zoai:scielo:S0104-42302016000800782Revistahttps://ramb.amb.org.br/ultimas-edicoes/#https://old.scielo.br/oai/scielo-oai.php||ramb@amb.org.br1806-92820104-4230opendoar:2016-12-15T00:00Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)false
dc.title.none.fl_str_mv Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
title Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
spellingShingle Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
Moraes,Fabio Ynoe
stereotactic body radiotherapy
radiation oncology
lung neoplasm
radiosurgery
title_short Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
title_full Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
title_fullStr Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
title_full_unstemmed Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
title_sort Emerging radiotherapy technology in a developing country: A single Brazilian institution assessment of stereotactic body radiotherapy application
author Moraes,Fabio Ynoe
author_facet Moraes,Fabio Ynoe
Bonifacio,Lorine Arias
Neves-Junior,Wellington Pimenta
Hanna,Samir Abdallah
Abreu,Carlos Eduardo Cintra Vita
Arruda,Fernando Freire
Silva,João Luis Fernandes
Carvalho,Heloisa Andrade
author_role author
author2 Bonifacio,Lorine Arias
Neves-Junior,Wellington Pimenta
Hanna,Samir Abdallah
Abreu,Carlos Eduardo Cintra Vita
Arruda,Fernando Freire
Silva,João Luis Fernandes
Carvalho,Heloisa Andrade
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moraes,Fabio Ynoe
Bonifacio,Lorine Arias
Neves-Junior,Wellington Pimenta
Hanna,Samir Abdallah
Abreu,Carlos Eduardo Cintra Vita
Arruda,Fernando Freire
Silva,João Luis Fernandes
Carvalho,Heloisa Andrade
dc.subject.por.fl_str_mv stereotactic body radiotherapy
radiation oncology
lung neoplasm
radiosurgery
topic stereotactic body radiotherapy
radiation oncology
lung neoplasm
radiosurgery
description Summary Objective: To provide a quantitative profile of the indications and use of stereotactic body radiotherapy (SBRT) in a developing country oncology-based institution. In addition, to describe the patients' and treatment characteristics, and to provide a temporal analysis. Method: SBRT patients treated from 2007 to 2015 were retrospectively evaluated by two independently investigators. Data were stratified and compared in two periods: first experience (FE) (May 2007 to April 2011), and following experience (FollowE) (May 2011 to April 2015). The following parameters were compared between the groups: total number of treated patients and lesions, treatment site, additional image fusion used, formal protocol adoption, and SBRT planning technique. Results: One hundred and seventy-six (176) patients with 191 lesions were treated: 34 (18%) lesions in the FE and 157 (82%) lesions in FollowE. The majority of lesions were metastases (60.3%), and lung (60.2%) was the most common treatment site, followed by spine (31%), and others (8.8%). An average of 1.4 (±0.6) additional imaging exams for delineation was performed. Conformal 3D radiotherapy planning technique was used in 64.4%, and intensity modulated radiotherapy (IMRT) or volumetric-modulated arc therapy (VMAT) in the remaining 35.6% (p=0.0001). Higher rates of curative treatments were observed in FE, as well as more lung lesions, patients ≥ 70 years, 3D conformal, number of additional images and ECOG 0, and all presented p<0.05. The global rate of protocol statement was 79%, lung treatment being the most stated. Conclusion: SBRT application is rapidly increasing in our setting. Treatment sites and planning techniques are becoming more diversified and complex.
publishDate 2016
dc.date.none.fl_str_mv 2016-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9282.62.08.782
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Médica Brasileira
publisher.none.fl_str_mv Associação Médica Brasileira
dc.source.none.fl_str_mv Revista da Associação Médica Brasileira v.62 n.8 2016
reponame:Revista da Associação Médica Brasileira (Online)
instname:Associação Médica Brasileira (AMB)
instacron:AMB
instname_str Associação Médica Brasileira (AMB)
instacron_str AMB
institution AMB
reponame_str Revista da Associação Médica Brasileira (Online)
collection Revista da Associação Médica Brasileira (Online)
repository.name.fl_str_mv Revista da Associação Médica Brasileira (Online) - Associação Médica Brasileira (AMB)
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