Neuropsychological alterations in mercury intoxication persist several years after exposure

Detalhes bibliográficos
Autor(a) principal: Zachi,Elaine Cristina
Data de Publicação: 2008
Outros Autores: Taub,Anita, Faria,Marcília de Araújo Medrado, Ventura,Dora Fix
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Dementia & Neuropsychologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642008000200091
Resumo: Abstract Elemental mercury is a liquid toxic metal widely used in industry. Occupational exposure occurs mainly via inhalation. Previously, neuropsychological assessment detected deficits in former workers of a fluorescent lamp plant who had been exposed to elemental mercury vapor and were away from exposure for several years at the time of examination. Objectives: The purpose of this work was to reexamine these functions after 18 months in order to evaluate their progression. Methods: Thirteen participants completed tests of attention, inhibitory control, verbal/visual memory, psychomotor speed, verbal fluency, visuomotor ability, executive function, semantic knowledge, and depression and anxiety inventories on 2 separate occasions. Results: At baseline, the former workers indicated slower psychomotor and information processing speed, verbal spontaneous recall memory impairment, and increased depression and anxiety symptoms compared to controls (P<0.05). Paired comparisons of neuropsychological functioning within the exposed group at baseline and 1.5 years later showed poorer immediate memory performance (P<0.05). There were no differences on other measures. Conclusions: Although the literature show signs of recovery of functions, the neuropsychological effects related to mercury exposure are found to persist for many years.
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spelling Neuropsychological alterations in mercury intoxication persist several years after exposuremercuryoccupational exposurecognition disordersneuropsychological testsmoodAbstract Elemental mercury is a liquid toxic metal widely used in industry. Occupational exposure occurs mainly via inhalation. Previously, neuropsychological assessment detected deficits in former workers of a fluorescent lamp plant who had been exposed to elemental mercury vapor and were away from exposure for several years at the time of examination. Objectives: The purpose of this work was to reexamine these functions after 18 months in order to evaluate their progression. Methods: Thirteen participants completed tests of attention, inhibitory control, verbal/visual memory, psychomotor speed, verbal fluency, visuomotor ability, executive function, semantic knowledge, and depression and anxiety inventories on 2 separate occasions. Results: At baseline, the former workers indicated slower psychomotor and information processing speed, verbal spontaneous recall memory impairment, and increased depression and anxiety symptoms compared to controls (P<0.05). Paired comparisons of neuropsychological functioning within the exposed group at baseline and 1.5 years later showed poorer immediate memory performance (P<0.05). There were no differences on other measures. Conclusions: Although the literature show signs of recovery of functions, the neuropsychological effects related to mercury exposure are found to persist for many years.Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento2008-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642008000200091Dementia &amp; Neuropsychologia v.2 n.2 2008reponame:Dementia & Neuropsychologiainstname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)instacron:ANCC10.1590/S1980-57642009DN20200003info:eu-repo/semantics/openAccessZachi,Elaine CristinaTaub,AnitaFaria,Marcília de Araújo MedradoVentura,Dora Fixeng2016-09-13T00:00:00Zoai:scielo:S1980-57642008000200091Revistahttp://www.demneuropsy.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||demneuropsy@uol.com.br1980-57641980-5764opendoar:2016-09-13T00:00Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)false
dc.title.none.fl_str_mv Neuropsychological alterations in mercury intoxication persist several years after exposure
title Neuropsychological alterations in mercury intoxication persist several years after exposure
spellingShingle Neuropsychological alterations in mercury intoxication persist several years after exposure
Zachi,Elaine Cristina
mercury
occupational exposure
cognition disorders
neuropsychological tests
mood
title_short Neuropsychological alterations in mercury intoxication persist several years after exposure
title_full Neuropsychological alterations in mercury intoxication persist several years after exposure
title_fullStr Neuropsychological alterations in mercury intoxication persist several years after exposure
title_full_unstemmed Neuropsychological alterations in mercury intoxication persist several years after exposure
title_sort Neuropsychological alterations in mercury intoxication persist several years after exposure
author Zachi,Elaine Cristina
author_facet Zachi,Elaine Cristina
Taub,Anita
Faria,Marcília de Araújo Medrado
Ventura,Dora Fix
author_role author
author2 Taub,Anita
Faria,Marcília de Araújo Medrado
Ventura,Dora Fix
author2_role author
author
author
dc.contributor.author.fl_str_mv Zachi,Elaine Cristina
Taub,Anita
Faria,Marcília de Araújo Medrado
Ventura,Dora Fix
dc.subject.por.fl_str_mv mercury
occupational exposure
cognition disorders
neuropsychological tests
mood
topic mercury
occupational exposure
cognition disorders
neuropsychological tests
mood
description Abstract Elemental mercury is a liquid toxic metal widely used in industry. Occupational exposure occurs mainly via inhalation. Previously, neuropsychological assessment detected deficits in former workers of a fluorescent lamp plant who had been exposed to elemental mercury vapor and were away from exposure for several years at the time of examination. Objectives: The purpose of this work was to reexamine these functions after 18 months in order to evaluate their progression. Methods: Thirteen participants completed tests of attention, inhibitory control, verbal/visual memory, psychomotor speed, verbal fluency, visuomotor ability, executive function, semantic knowledge, and depression and anxiety inventories on 2 separate occasions. Results: At baseline, the former workers indicated slower psychomotor and information processing speed, verbal spontaneous recall memory impairment, and increased depression and anxiety symptoms compared to controls (P<0.05). Paired comparisons of neuropsychological functioning within the exposed group at baseline and 1.5 years later showed poorer immediate memory performance (P<0.05). There were no differences on other measures. Conclusions: Although the literature show signs of recovery of functions, the neuropsychological effects related to mercury exposure are found to persist for many years.
publishDate 2008
dc.date.none.fl_str_mv 2008-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642008000200091
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642008000200091
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1980-57642009DN20200003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
dc.source.none.fl_str_mv Dementia &amp; Neuropsychologia v.2 n.2 2008
reponame:Dementia & Neuropsychologia
instname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron:ANCC
instname_str Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron_str ANCC
institution ANCC
reponame_str Dementia & Neuropsychologia
collection Dementia & Neuropsychologia
repository.name.fl_str_mv Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)
repository.mail.fl_str_mv ||demneuropsy@uol.com.br
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