Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Dementia & Neuropsychologia |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300308 |
Resumo: | ABSTRACT Cognitive deficits in cancer patients can be related to depression, anxiety, and the side effects of treatments such as fatigue. In this case report, we described an elderly patient with rectal adenocarcinoma, which presented depressive symptoms and memory complaints after treatment with 5-Fluoracil and Leucovorin. Depressive symptoms improved after two months but cognitive and functional impairment worsened suggesting the diagnosis of mild dementia. Structural and functional brain changes were seen on neuroimaging exams. Rivastigmine was introduced up to 12 mg/day, and after a one-year follow up the patient remained stable. Cognitive deficits can be a consequence of cancer therapies and a protocol to investigate deficits cognitive could be useful to the diferential diagnosis and management of elderly cancer patients submitted to chemotherapy. |
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Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case reportcognitive deficitsdementiacancerchemotherapy5-Fluoracil.ABSTRACT Cognitive deficits in cancer patients can be related to depression, anxiety, and the side effects of treatments such as fatigue. In this case report, we described an elderly patient with rectal adenocarcinoma, which presented depressive symptoms and memory complaints after treatment with 5-Fluoracil and Leucovorin. Depressive symptoms improved after two months but cognitive and functional impairment worsened suggesting the diagnosis of mild dementia. Structural and functional brain changes were seen on neuroimaging exams. Rivastigmine was introduced up to 12 mg/day, and after a one-year follow up the patient remained stable. Cognitive deficits can be a consequence of cancer therapies and a protocol to investigate deficits cognitive could be useful to the diferential diagnosis and management of elderly cancer patients submitted to chemotherapy.Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento2013-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300308Dementia & Neuropsychologia v.7 n.3 2013reponame:Dementia & Neuropsychologiainstname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)instacron:ANCC10.1590/S1980-57642013DN70300013info:eu-repo/semantics/openAccessBottino,Sara Mota BorgesGarcia,Célia Petrossi GalloViana,Bernardo de MattosBottino,Cássio Machado de Camposeng2016-05-13T00:00:00Zoai:scielo:S1980-57642013000300308Revistahttp://www.demneuropsy.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||demneuropsy@uol.com.br1980-57641980-5764opendoar:2016-05-13T00:00Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)false |
dc.title.none.fl_str_mv |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
title |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
spellingShingle |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report Bottino,Sara Mota Borges cognitive deficits dementia cancer chemotherapy 5-Fluoracil. |
title_short |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
title_full |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
title_fullStr |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
title_full_unstemmed |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
title_sort |
Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report |
author |
Bottino,Sara Mota Borges |
author_facet |
Bottino,Sara Mota Borges Garcia,Célia Petrossi Gallo Viana,Bernardo de Mattos Bottino,Cássio Machado de Campos |
author_role |
author |
author2 |
Garcia,Célia Petrossi Gallo Viana,Bernardo de Mattos Bottino,Cássio Machado de Campos |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Bottino,Sara Mota Borges Garcia,Célia Petrossi Gallo Viana,Bernardo de Mattos Bottino,Cássio Machado de Campos |
dc.subject.por.fl_str_mv |
cognitive deficits dementia cancer chemotherapy 5-Fluoracil. |
topic |
cognitive deficits dementia cancer chemotherapy 5-Fluoracil. |
description |
ABSTRACT Cognitive deficits in cancer patients can be related to depression, anxiety, and the side effects of treatments such as fatigue. In this case report, we described an elderly patient with rectal adenocarcinoma, which presented depressive symptoms and memory complaints after treatment with 5-Fluoracil and Leucovorin. Depressive symptoms improved after two months but cognitive and functional impairment worsened suggesting the diagnosis of mild dementia. Structural and functional brain changes were seen on neuroimaging exams. Rivastigmine was introduced up to 12 mg/day, and after a one-year follow up the patient remained stable. Cognitive deficits can be a consequence of cancer therapies and a protocol to investigate deficits cognitive could be useful to the diferential diagnosis and management of elderly cancer patients submitted to chemotherapy. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300308 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300308 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1980-57642013DN70300013 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento |
dc.source.none.fl_str_mv |
Dementia & Neuropsychologia v.7 n.3 2013 reponame:Dementia & Neuropsychologia instname:Associação de Neurologia Cognitiva e do Comportamento (ANCC) instacron:ANCC |
instname_str |
Associação de Neurologia Cognitiva e do Comportamento (ANCC) |
instacron_str |
ANCC |
institution |
ANCC |
reponame_str |
Dementia & Neuropsychologia |
collection |
Dementia & Neuropsychologia |
repository.name.fl_str_mv |
Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC) |
repository.mail.fl_str_mv |
||demneuropsy@uol.com.br |
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1754212930640936960 |