Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802003000600006 |
Resumo: | CONTEXT: Patients with antiphospholipid syndrome and alloimmunity have poor pregnancy outcomes. Several diagnostic and therapeutic options exist for these disorders, although there is no consensus as to the best treatment. CASE REPORT: We present here the clinical course and treatment of a woman with a history of two miscarriages who joined our program 10 years ago and has been followed up ever since. After antiphospholipid syndrome and alloimmune failure were diagnosed, she was given preconceptional treatment using unfractionated heparin, aspirin, prednisone and lymphocyte immunizations. She delivered two premature babies in the following two pregnancies. At present both children are healthy and are attending school. The fifth pregnancy was unsuccessful, in spite of having undergone a similar but postconceptional therapeutic scheme. We discuss this case focusing on the pathogenic mechanisms and the therapeutic aspects of these disorders. |
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Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case reportAntiphospholipid syndromeHabitual abortionHeparinAspirinImmunotherapyCONTEXT: Patients with antiphospholipid syndrome and alloimmunity have poor pregnancy outcomes. Several diagnostic and therapeutic options exist for these disorders, although there is no consensus as to the best treatment. CASE REPORT: We present here the clinical course and treatment of a woman with a history of two miscarriages who joined our program 10 years ago and has been followed up ever since. After antiphospholipid syndrome and alloimmune failure were diagnosed, she was given preconceptional treatment using unfractionated heparin, aspirin, prednisone and lymphocyte immunizations. She delivered two premature babies in the following two pregnancies. At present both children are healthy and are attending school. The fifth pregnancy was unsuccessful, in spite of having undergone a similar but postconceptional therapeutic scheme. We discuss this case focusing on the pathogenic mechanisms and the therapeutic aspects of these disorders.Associação Paulista de Medicina - APM2003-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802003000600006Sao Paulo Medical Journal v.121 n.6 2003reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802003000600006info:eu-repo/semantics/openAccessCastañeda Ospina,Serguei AbelCardona Maya,Wálter DaríoBueno Sánchez,Julio CésarCadavid Jaramillo,Ángela Patriciaeng2004-06-25T00:00:00Zoai:scielo:S1516-31802003000600006Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2004-06-25T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
title |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
spellingShingle |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report Castañeda Ospina,Serguei Abel Antiphospholipid syndrome Habitual abortion Heparin Aspirin Immunotherapy |
title_short |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
title_full |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
title_fullStr |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
title_full_unstemmed |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
title_sort |
Pregnancy outcome in women with antiphospholipid syndrome and alloimmunity: a case report |
author |
Castañeda Ospina,Serguei Abel |
author_facet |
Castañeda Ospina,Serguei Abel Cardona Maya,Wálter Darío Bueno Sánchez,Julio César Cadavid Jaramillo,Ángela Patricia |
author_role |
author |
author2 |
Cardona Maya,Wálter Darío Bueno Sánchez,Julio César Cadavid Jaramillo,Ángela Patricia |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Castañeda Ospina,Serguei Abel Cardona Maya,Wálter Darío Bueno Sánchez,Julio César Cadavid Jaramillo,Ángela Patricia |
dc.subject.por.fl_str_mv |
Antiphospholipid syndrome Habitual abortion Heparin Aspirin Immunotherapy |
topic |
Antiphospholipid syndrome Habitual abortion Heparin Aspirin Immunotherapy |
description |
CONTEXT: Patients with antiphospholipid syndrome and alloimmunity have poor pregnancy outcomes. Several diagnostic and therapeutic options exist for these disorders, although there is no consensus as to the best treatment. CASE REPORT: We present here the clinical course and treatment of a woman with a history of two miscarriages who joined our program 10 years ago and has been followed up ever since. After antiphospholipid syndrome and alloimmune failure were diagnosed, she was given preconceptional treatment using unfractionated heparin, aspirin, prednisone and lymphocyte immunizations. She delivered two premature babies in the following two pregnancies. At present both children are healthy and are attending school. The fifth pregnancy was unsuccessful, in spite of having undergone a similar but postconceptional therapeutic scheme. We discuss this case focusing on the pathogenic mechanisms and the therapeutic aspects of these disorders. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802003000600006 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802003000600006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-31802003000600006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.121 n.6 2003 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1754209260821020672 |