A t (9;11) translocation in childhood acute mixed leukemia
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004 |
Resumo: | We present the case of a child with acute lymphoid leukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19, CD13 and CD33 were positive) with t (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondary mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning. |
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A t (9;11) translocation in childhood acute mixed leukemiaLeukemiakaryotipeEpipodophillotoxin derivativeWe present the case of a child with acute lymphoid leukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19, CD13 and CD33 were positive) with t (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondary mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning.Associação Paulista de Medicina - APM1996-04-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004Sao Paulo Medical Journal v.114 n.2 1996reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31801996000200004info:eu-repo/semantics/openAccessChauffaille,Maria de Lourdes Lopes FerrariYamamoto,MihokoOdone Filho,VicenteAlmeida,Maria TherezaMaluf Jr.,PauloCristofani,Lilian M.Kerbauy,JoséRaimondi,Suzana C.eng2008-11-19T00:00:00Zoai:scielo:S1516-31801996000200004Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2008-11-19T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
A t (9;11) translocation in childhood acute mixed leukemia |
title |
A t (9;11) translocation in childhood acute mixed leukemia |
spellingShingle |
A t (9;11) translocation in childhood acute mixed leukemia Chauffaille,Maria de Lourdes Lopes Ferrari Leukemia karyotipe Epipodophillotoxin derivative |
title_short |
A t (9;11) translocation in childhood acute mixed leukemia |
title_full |
A t (9;11) translocation in childhood acute mixed leukemia |
title_fullStr |
A t (9;11) translocation in childhood acute mixed leukemia |
title_full_unstemmed |
A t (9;11) translocation in childhood acute mixed leukemia |
title_sort |
A t (9;11) translocation in childhood acute mixed leukemia |
author |
Chauffaille,Maria de Lourdes Lopes Ferrari |
author_facet |
Chauffaille,Maria de Lourdes Lopes Ferrari Yamamoto,Mihoko Odone Filho,Vicente Almeida,Maria Thereza Maluf Jr.,Paulo Cristofani,Lilian M. Kerbauy,José Raimondi,Suzana C. |
author_role |
author |
author2 |
Yamamoto,Mihoko Odone Filho,Vicente Almeida,Maria Thereza Maluf Jr.,Paulo Cristofani,Lilian M. Kerbauy,José Raimondi,Suzana C. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Chauffaille,Maria de Lourdes Lopes Ferrari Yamamoto,Mihoko Odone Filho,Vicente Almeida,Maria Thereza Maluf Jr.,Paulo Cristofani,Lilian M. Kerbauy,José Raimondi,Suzana C. |
dc.subject.por.fl_str_mv |
Leukemia karyotipe Epipodophillotoxin derivative |
topic |
Leukemia karyotipe Epipodophillotoxin derivative |
description |
We present the case of a child with acute lymphoid leukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19, CD13 and CD33 were positive) with t (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondary mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-31801996000200004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.114 n.2 1996 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1754209259510300672 |