A t (9;11) translocation in childhood acute mixed leukemia

Detalhes bibliográficos
Autor(a) principal: Chauffaille,Maria de Lourdes Lopes Ferrari
Data de Publicação: 1996
Outros Autores: Yamamoto,Mihoko, Odone Filho,Vicente, Almeida,Maria Thereza, Maluf Jr.,Paulo, Cristofani,Lilian M., Kerbauy,José, Raimondi,Suzana C.
Tipo de documento: Relatório
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004
Resumo: We present the case of a child with acute lymphoid leukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19, CD13 and CD33 were positive) with t (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondary mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning.
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spelling A t (9;11) translocation in childhood acute mixed leukemiaLeukemiakaryotipeEpipodophillotoxin derivativeWe present the case of a child with acute lymphoid leukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19, CD13 and CD33 were positive) with t (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondary mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning.Associação Paulista de Medicina - APM1996-04-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004Sao Paulo Medical Journal v.114 n.2 1996reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31801996000200004info:eu-repo/semantics/openAccessChauffaille,Maria de Lourdes Lopes FerrariYamamoto,MihokoOdone Filho,VicenteAlmeida,Maria TherezaMaluf Jr.,PauloCristofani,Lilian M.Kerbauy,JoséRaimondi,Suzana C.eng2008-11-19T00:00:00Zoai:scielo:S1516-31801996000200004Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2008-11-19T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv A t (9;11) translocation in childhood acute mixed leukemia
title A t (9;11) translocation in childhood acute mixed leukemia
spellingShingle A t (9;11) translocation in childhood acute mixed leukemia
Chauffaille,Maria de Lourdes Lopes Ferrari
Leukemia
karyotipe
Epipodophillotoxin derivative
title_short A t (9;11) translocation in childhood acute mixed leukemia
title_full A t (9;11) translocation in childhood acute mixed leukemia
title_fullStr A t (9;11) translocation in childhood acute mixed leukemia
title_full_unstemmed A t (9;11) translocation in childhood acute mixed leukemia
title_sort A t (9;11) translocation in childhood acute mixed leukemia
author Chauffaille,Maria de Lourdes Lopes Ferrari
author_facet Chauffaille,Maria de Lourdes Lopes Ferrari
Yamamoto,Mihoko
Odone Filho,Vicente
Almeida,Maria Thereza
Maluf Jr.,Paulo
Cristofani,Lilian M.
Kerbauy,José
Raimondi,Suzana C.
author_role author
author2 Yamamoto,Mihoko
Odone Filho,Vicente
Almeida,Maria Thereza
Maluf Jr.,Paulo
Cristofani,Lilian M.
Kerbauy,José
Raimondi,Suzana C.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Chauffaille,Maria de Lourdes Lopes Ferrari
Yamamoto,Mihoko
Odone Filho,Vicente
Almeida,Maria Thereza
Maluf Jr.,Paulo
Cristofani,Lilian M.
Kerbauy,José
Raimondi,Suzana C.
dc.subject.por.fl_str_mv Leukemia
karyotipe
Epipodophillotoxin derivative
topic Leukemia
karyotipe
Epipodophillotoxin derivative
description We present the case of a child with acute lymphoid leukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19, CD13 and CD33 were positive) with t (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondary mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning.
publishDate 1996
dc.date.none.fl_str_mv 1996-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000200004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31801996000200004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.114 n.2 1996
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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