What do Cochrane systematic reviews say about the management of irritable bowel syndrome?
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802019000100082 |
Resumo: | ABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is a clinical disorder associated with high socioeconomic burden. Despite its importance, management of IBS remains difficult and several interventions have been hypothesized as beneficial for this condition. This study identified and summarized all Cochrane systematic reviews (SRs) about the effects of interventions for managing IBS patients. DESIGN AND SETTING: Review of systematic reviews, carried out in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP). METHODS: Review of Cochrane SRs addressing interventions for IBS. RESULTS: We included six SRs assessing acupuncture, bulking agents, antispasmodics, antidepressants, herbal medicines, homeopathy, hypnotherapy and psychological therapy for IBS. The certainty of evidence ranged from unknown to moderate, mainly due to imprecision in the estimates and high risk of bias from the primary studies included. There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life, compared with sham acupuncture. There was also very low certainty of evidence that homeopathic asafoetida, used alone or in association with nux, was better than placebo regarding self-reported overall improvement. CONCLUSION: There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life. Further well-designed and well-conducted randomized clinical trials are needed in order to reduce the uncertainties regarding the most commonly used interventions for patients with IBS. |
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What do Cochrane systematic reviews say about the management of irritable bowel syndrome?Review [publication type]Irritable bowel syndromeColonic diseases, functionalEvidence-based medicineEvidence-based practiceABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is a clinical disorder associated with high socioeconomic burden. Despite its importance, management of IBS remains difficult and several interventions have been hypothesized as beneficial for this condition. This study identified and summarized all Cochrane systematic reviews (SRs) about the effects of interventions for managing IBS patients. DESIGN AND SETTING: Review of systematic reviews, carried out in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP). METHODS: Review of Cochrane SRs addressing interventions for IBS. RESULTS: We included six SRs assessing acupuncture, bulking agents, antispasmodics, antidepressants, herbal medicines, homeopathy, hypnotherapy and psychological therapy for IBS. The certainty of evidence ranged from unknown to moderate, mainly due to imprecision in the estimates and high risk of bias from the primary studies included. There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life, compared with sham acupuncture. There was also very low certainty of evidence that homeopathic asafoetida, used alone or in association with nux, was better than placebo regarding self-reported overall improvement. CONCLUSION: There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life. Further well-designed and well-conducted randomized clinical trials are needed in order to reduce the uncertainties regarding the most commonly used interventions for patients with IBS.Associação Paulista de Medicina - APM2019-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802019000100082Sao Paulo Medical Journal v.137 n.1 2019reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/1516-3180.2018.053740119info:eu-repo/semantics/openAccessPacheco,Rafael LeiteRoizenblatt,ArnaldoGóis,Aécio Flávio Teixeira deLatorraca,Carolina de Oliveira CruzMota,Carolina Frade Magalhães Girardin PimentelRiera,Racheleng2019-05-14T00:00:00Zoai:scielo:S1516-31802019000100082Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2019-05-14T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
title |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
spellingShingle |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? Pacheco,Rafael Leite Review [publication type] Irritable bowel syndrome Colonic diseases, functional Evidence-based medicine Evidence-based practice |
title_short |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
title_full |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
title_fullStr |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
title_full_unstemmed |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
title_sort |
What do Cochrane systematic reviews say about the management of irritable bowel syndrome? |
author |
Pacheco,Rafael Leite |
author_facet |
Pacheco,Rafael Leite Roizenblatt,Arnaldo Góis,Aécio Flávio Teixeira de Latorraca,Carolina de Oliveira Cruz Mota,Carolina Frade Magalhães Girardin Pimentel Riera,Rachel |
author_role |
author |
author2 |
Roizenblatt,Arnaldo Góis,Aécio Flávio Teixeira de Latorraca,Carolina de Oliveira Cruz Mota,Carolina Frade Magalhães Girardin Pimentel Riera,Rachel |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pacheco,Rafael Leite Roizenblatt,Arnaldo Góis,Aécio Flávio Teixeira de Latorraca,Carolina de Oliveira Cruz Mota,Carolina Frade Magalhães Girardin Pimentel Riera,Rachel |
dc.subject.por.fl_str_mv |
Review [publication type] Irritable bowel syndrome Colonic diseases, functional Evidence-based medicine Evidence-based practice |
topic |
Review [publication type] Irritable bowel syndrome Colonic diseases, functional Evidence-based medicine Evidence-based practice |
description |
ABSTRACT BACKGROUND: Irritable bowel syndrome (IBS) is a clinical disorder associated with high socioeconomic burden. Despite its importance, management of IBS remains difficult and several interventions have been hypothesized as beneficial for this condition. This study identified and summarized all Cochrane systematic reviews (SRs) about the effects of interventions for managing IBS patients. DESIGN AND SETTING: Review of systematic reviews, carried out in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP). METHODS: Review of Cochrane SRs addressing interventions for IBS. RESULTS: We included six SRs assessing acupuncture, bulking agents, antispasmodics, antidepressants, herbal medicines, homeopathy, hypnotherapy and psychological therapy for IBS. The certainty of evidence ranged from unknown to moderate, mainly due to imprecision in the estimates and high risk of bias from the primary studies included. There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life, compared with sham acupuncture. There was also very low certainty of evidence that homeopathic asafoetida, used alone or in association with nux, was better than placebo regarding self-reported overall improvement. CONCLUSION: There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life. Further well-designed and well-conducted randomized clinical trials are needed in order to reduce the uncertainties regarding the most commonly used interventions for patients with IBS. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802019000100082 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802019000100082 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1516-3180.2018.053740119 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.137 n.1 2019 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1754209266619645952 |