Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil

Detalhes bibliográficos
Autor(a) principal: Trovão,Leandro de Oliveira
Data de Publicação: 2022
Outros Autores: Alves,Gilberto Sousa, Carrilho,Carolina Gomes, Ricci,Thaysse Gomes, Bittencourt,Lays, Alves,Cândida, Brito,Natália Costa, Nardi,Antonio Egídio, Malaspina,Dolores, Veras,André Barciela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Trends in Psychiatry and Psychotherapy
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419
Resumo: Abstract Objectives To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms. Methods Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration. Results Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303). Conclusions Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression.
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spelling Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in BrazilEarly traumaschizophreniaabusedepressionAbstract Objectives To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms. Methods Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration. Results Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303). Conclusions Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression.Associação de Psiquiatria do Rio Grande do Sul2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419Trends in Psychiatry and Psychotherapy v.44 2022reponame:Trends in Psychiatry and Psychotherapyinstname:Sociedade de Psiquiatria do Rio Grande do Sulinstacron:APRGS10.47626/2237-6089-2020-0024info:eu-repo/semantics/openAccessTrovão,Leandro de OliveiraAlves,Gilberto SousaCarrilho,Carolina GomesRicci,Thaysse GomesBittencourt,LaysAlves,CândidaBrito,Natália CostaNardi,Antonio EgídioMalaspina,DoloresVeras,André Barcielaeng2022-10-27T00:00:00Zoai:scielo:S2237-60892022000100419Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-6089&lng=en&nrm=isohttps://old.scielo.br/oai/scielo-oai.phprevista@aprs.org.br|| rodrigo_grassi@terra.com.br2238-00192237-6089opendoar:2022-10-27T00:00Trends in Psychiatry and Psychotherapy - Sociedade de Psiquiatria do Rio Grande do Sulfalse
dc.title.none.fl_str_mv Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
title Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
spellingShingle Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
Trovão,Leandro de Oliveira
Early trauma
schizophrenia
abuse
depression
title_short Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
title_full Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
title_fullStr Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
title_full_unstemmed Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
title_sort Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
author Trovão,Leandro de Oliveira
author_facet Trovão,Leandro de Oliveira
Alves,Gilberto Sousa
Carrilho,Carolina Gomes
Ricci,Thaysse Gomes
Bittencourt,Lays
Alves,Cândida
Brito,Natália Costa
Nardi,Antonio Egídio
Malaspina,Dolores
Veras,André Barciela
author_role author
author2 Alves,Gilberto Sousa
Carrilho,Carolina Gomes
Ricci,Thaysse Gomes
Bittencourt,Lays
Alves,Cândida
Brito,Natália Costa
Nardi,Antonio Egídio
Malaspina,Dolores
Veras,André Barciela
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Trovão,Leandro de Oliveira
Alves,Gilberto Sousa
Carrilho,Carolina Gomes
Ricci,Thaysse Gomes
Bittencourt,Lays
Alves,Cândida
Brito,Natália Costa
Nardi,Antonio Egídio
Malaspina,Dolores
Veras,André Barciela
dc.subject.por.fl_str_mv Early trauma
schizophrenia
abuse
depression
topic Early trauma
schizophrenia
abuse
depression
description Abstract Objectives To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms. Methods Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration. Results Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303). Conclusions Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.47626/2237-6089-2020-0024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação de Psiquiatria do Rio Grande do Sul
publisher.none.fl_str_mv Associação de Psiquiatria do Rio Grande do Sul
dc.source.none.fl_str_mv Trends in Psychiatry and Psychotherapy v.44 2022
reponame:Trends in Psychiatry and Psychotherapy
instname:Sociedade de Psiquiatria do Rio Grande do Sul
instacron:APRGS
instname_str Sociedade de Psiquiatria do Rio Grande do Sul
instacron_str APRGS
institution APRGS
reponame_str Trends in Psychiatry and Psychotherapy
collection Trends in Psychiatry and Psychotherapy
repository.name.fl_str_mv Trends in Psychiatry and Psychotherapy - Sociedade de Psiquiatria do Rio Grande do Sul
repository.mail.fl_str_mv revista@aprs.org.br|| rodrigo_grassi@terra.com.br
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