Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Trends in Psychiatry and Psychotherapy |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419 |
Resumo: | Abstract Objectives To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms. Methods Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration. Results Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303). Conclusions Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression. |
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Trends in Psychiatry and Psychotherapy |
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Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in BrazilEarly traumaschizophreniaabusedepressionAbstract Objectives To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms. Methods Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration. Results Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303). Conclusions Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression.Associação de Psiquiatria do Rio Grande do Sul2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419Trends in Psychiatry and Psychotherapy v.44 2022reponame:Trends in Psychiatry and Psychotherapyinstname:Sociedade de Psiquiatria do Rio Grande do Sulinstacron:APRGS10.47626/2237-6089-2020-0024info:eu-repo/semantics/openAccessTrovão,Leandro de OliveiraAlves,Gilberto SousaCarrilho,Carolina GomesRicci,Thaysse GomesBittencourt,LaysAlves,CândidaBrito,Natália CostaNardi,Antonio EgídioMalaspina,DoloresVeras,André Barcielaeng2022-10-27T00:00:00Zoai:scielo:S2237-60892022000100419Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=2237-6089&lng=en&nrm=isohttps://old.scielo.br/oai/scielo-oai.phprevista@aprs.org.br|| rodrigo_grassi@terra.com.br2238-00192237-6089opendoar:2022-10-27T00:00Trends in Psychiatry and Psychotherapy - Sociedade de Psiquiatria do Rio Grande do Sulfalse |
dc.title.none.fl_str_mv |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
title |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
spellingShingle |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil Trovão,Leandro de Oliveira Early trauma schizophrenia abuse depression |
title_short |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
title_full |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
title_fullStr |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
title_full_unstemmed |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
title_sort |
Early trauma and schizophrenia onset: preliminary results of an outpatient cohort in Brazil |
author |
Trovão,Leandro de Oliveira |
author_facet |
Trovão,Leandro de Oliveira Alves,Gilberto Sousa Carrilho,Carolina Gomes Ricci,Thaysse Gomes Bittencourt,Lays Alves,Cândida Brito,Natália Costa Nardi,Antonio Egídio Malaspina,Dolores Veras,André Barciela |
author_role |
author |
author2 |
Alves,Gilberto Sousa Carrilho,Carolina Gomes Ricci,Thaysse Gomes Bittencourt,Lays Alves,Cândida Brito,Natália Costa Nardi,Antonio Egídio Malaspina,Dolores Veras,André Barciela |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Trovão,Leandro de Oliveira Alves,Gilberto Sousa Carrilho,Carolina Gomes Ricci,Thaysse Gomes Bittencourt,Lays Alves,Cândida Brito,Natália Costa Nardi,Antonio Egídio Malaspina,Dolores Veras,André Barciela |
dc.subject.por.fl_str_mv |
Early trauma schizophrenia abuse depression |
topic |
Early trauma schizophrenia abuse depression |
description |
Abstract Objectives To assess the prevalence of early trauma in individuals with onset of schizophrenia (SZ) at early (≤ 18 years) and adult (> 18 years) ages (EOP and AOP, respectively) and explore relationships between the onset of disease and clinical variables including traumatic events and psychotic and mood symptoms. Methods Subjects with SZ (n = 71) and EOP and AOP were compared for history of psychological trauma, sexual abuse, and physical punishment using the Early Trauma Inventory Self Report - Short Form (ETISR-SF). They were also compared for history of comorbidities and affective disorders using the Diagnostic Interview for Psychosis and Affective Disorders, the Positive and Negative Syndrome Scale, the Liebowitz Social Anxiety Scale, and the Calgary Depression Scale for Schizophrenia. Coefficients were calculated for correlations between scale results and disease duration. Results Early trauma was significantly associated with an early onset psychotic episode (r = -0.315, p < 0.01). General trauma and depressive symptoms in adulthood were also associated (r = 0.442, p < 0.01), as were social anxiety symptoms and early trauma (r = 0.319, p < 0.01). Total ETISR-SF scores and the physical abuse item were significantly higher in EOP than in AOP. In the hierarchical regression, PANSS scores were best predicted by a model including the duration of disease and age of first psychotic episode (R = 0.303). Conclusions Our results support the hypothesis that early trauma, including physical abuse, may play a relevant role in schizophrenia symptoms, such as an earlier psychotic occurrence, as well as features of other psychiatric disorders, such as greater severity of social anxiety and depression. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-60892022000100419 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.47626/2237-6089-2020-0024 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação de Psiquiatria do Rio Grande do Sul |
publisher.none.fl_str_mv |
Associação de Psiquiatria do Rio Grande do Sul |
dc.source.none.fl_str_mv |
Trends in Psychiatry and Psychotherapy v.44 2022 reponame:Trends in Psychiatry and Psychotherapy instname:Sociedade de Psiquiatria do Rio Grande do Sul instacron:APRGS |
instname_str |
Sociedade de Psiquiatria do Rio Grande do Sul |
instacron_str |
APRGS |
institution |
APRGS |
reponame_str |
Trends in Psychiatry and Psychotherapy |
collection |
Trends in Psychiatry and Psychotherapy |
repository.name.fl_str_mv |
Trends in Psychiatry and Psychotherapy - Sociedade de Psiquiatria do Rio Grande do Sul |
repository.mail.fl_str_mv |
revista@aprs.org.br|| rodrigo_grassi@terra.com.br |
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1754209282109210624 |