Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens

Detalhes bibliográficos
Autor(a) principal: Filho, Cloves Gomes de Carvalho
Data de Publicação: 2021
Outros Autores: Filho, Luis Claudio Kellner, Picão, Bruno William, Ragozoni, Arthur Alves, Ribeiro, Arthur Barcelos, Nicolella, Heloiza Diniz, Squarisi, Iara Silva, Soares, Marcos Antonio, Tavares, Denise Crispim, Silva, Marcio Luis Andrade e, Cunha, Wilson Roberto, Pauletti, Patricia Mendonça, Januário, Ana Helena
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Applied Science Review
Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788
Resumo: Chemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens.
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spelling Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergensCambaráCerradoEndophytic fungusVochysiaceaeChemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens.Brazilian Journals Publicações de Periódicos e Editora Ltda.2021-04-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/2878810.34115/basrv5n2-046Brazilian Applied Science Review; Vol. 5 No. 2 (2021); 1244-1254Brazilian Applied Science Review; v. 5 n. 2 (2021); 1244-12542595-36212595-362110.34115/basr.v5i2reponame:Brazilian Applied Science Reviewinstname:Brazilian Journals Publicações de Periódicos e Editora Ltdainstacron:FIEPporhttps://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788/22749Copyright (c) 2021 Brazilian Applied Science Reviewinfo:eu-repo/semantics/openAccessFilho, Cloves Gomes de CarvalhoFilho, Luis Claudio KellnerPicão, Bruno WilliamRagozoni, Arthur AlvesRibeiro, Arthur BarcelosNicolella, Heloiza DinizSquarisi, Iara SilvaSoares, Marcos AntonioTavares, Denise CrispimSilva, Marcio Luis Andrade eCunha, Wilson RobertoPauletti, Patricia MendonçaJanuário, Ana Helena2021-04-28T16:37:23Zoai:ojs2.ojs.brazilianjournals.com.br:article/28788Revistahttps://www.brazilianjournals.com/index.php/BASRPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BASR/oaibrazilianasr@yahoo.com || brazilianasr@yahoo.com2595-36212595-3621opendoar:2021-04-28T16:37:23Brazilian Applied Science Review - Brazilian Journals Publicações de Periódicos e Editora Ltdafalse
dc.title.none.fl_str_mv Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
title Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
spellingShingle Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
Filho, Cloves Gomes de Carvalho
Cambará
Cerrado
Endophytic fungus
Vochysiaceae
title_short Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
title_full Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
title_fullStr Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
title_full_unstemmed Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
title_sort Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
author Filho, Cloves Gomes de Carvalho
author_facet Filho, Cloves Gomes de Carvalho
Filho, Luis Claudio Kellner
Picão, Bruno William
Ragozoni, Arthur Alves
Ribeiro, Arthur Barcelos
Nicolella, Heloiza Diniz
Squarisi, Iara Silva
Soares, Marcos Antonio
Tavares, Denise Crispim
Silva, Marcio Luis Andrade e
Cunha, Wilson Roberto
Pauletti, Patricia Mendonça
Januário, Ana Helena
author_role author
author2 Filho, Luis Claudio Kellner
Picão, Bruno William
Ragozoni, Arthur Alves
Ribeiro, Arthur Barcelos
Nicolella, Heloiza Diniz
Squarisi, Iara Silva
Soares, Marcos Antonio
Tavares, Denise Crispim
Silva, Marcio Luis Andrade e
Cunha, Wilson Roberto
Pauletti, Patricia Mendonça
Januário, Ana Helena
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Filho, Cloves Gomes de Carvalho
Filho, Luis Claudio Kellner
Picão, Bruno William
Ragozoni, Arthur Alves
Ribeiro, Arthur Barcelos
Nicolella, Heloiza Diniz
Squarisi, Iara Silva
Soares, Marcos Antonio
Tavares, Denise Crispim
Silva, Marcio Luis Andrade e
Cunha, Wilson Roberto
Pauletti, Patricia Mendonça
Januário, Ana Helena
dc.subject.por.fl_str_mv Cambará
Cerrado
Endophytic fungus
Vochysiaceae
topic Cambará
Cerrado
Endophytic fungus
Vochysiaceae
description Chemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-24
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788
10.34115/basrv5n2-046
url https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788
identifier_str_mv 10.34115/basrv5n2-046
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788/22749
dc.rights.driver.fl_str_mv Copyright (c) 2021 Brazilian Applied Science Review
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Brazilian Applied Science Review
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Brazilian Journals Publicações de Periódicos e Editora Ltda.
publisher.none.fl_str_mv Brazilian Journals Publicações de Periódicos e Editora Ltda.
dc.source.none.fl_str_mv Brazilian Applied Science Review; Vol. 5 No. 2 (2021); 1244-1254
Brazilian Applied Science Review; v. 5 n. 2 (2021); 1244-1254
2595-3621
2595-3621
10.34115/basr.v5i2
reponame:Brazilian Applied Science Review
instname:Brazilian Journals Publicações de Periódicos e Editora Ltda
instacron:FIEP
instname_str Brazilian Journals Publicações de Periódicos e Editora Ltda
instacron_str FIEP
institution FIEP
reponame_str Brazilian Applied Science Review
collection Brazilian Applied Science Review
repository.name.fl_str_mv Brazilian Applied Science Review - Brazilian Journals Publicações de Periódicos e Editora Ltda
repository.mail.fl_str_mv brazilianasr@yahoo.com || brazilianasr@yahoo.com
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