Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Brazilian Applied Science Review |
| Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788 |
Resumo: | Chemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens. |
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Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergensCambaráCerradoEndophytic fungusVochysiaceaeChemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens.Brazilian Journals Publicações de Periódicos e Editora Ltda.2021-04-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/2878810.34115/basrv5n2-046Brazilian Applied Science Review; Vol. 5 No. 2 (2021); 1244-1254Brazilian Applied Science Review; v. 5 n. 2 (2021); 1244-12542595-36212595-362110.34115/basr.v5i2reponame:Brazilian Applied Science Reviewinstname:Brazilian Journals Publicações de Periódicos e Editora Ltdainstacron:FIEPporhttps://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788/22749Copyright (c) 2021 Brazilian Applied Science Reviewinfo:eu-repo/semantics/openAccessFilho, Cloves Gomes de CarvalhoFilho, Luis Claudio KellnerPicão, Bruno WilliamRagozoni, Arthur AlvesRibeiro, Arthur BarcelosNicolella, Heloiza DinizSquarisi, Iara SilvaSoares, Marcos AntonioTavares, Denise CrispimSilva, Marcio Luis Andrade eCunha, Wilson RobertoPauletti, Patricia MendonçaJanuário, Ana Helena2021-04-28T16:37:23Zoai:ojs2.ojs.brazilianjournals.com.br:article/28788Revistahttps://www.brazilianjournals.com/index.php/BASRPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BASR/oaibrazilianasr@yahoo.com || brazilianasr@yahoo.com2595-36212595-3621opendoar:2021-04-28T16:37:23Brazilian Applied Science Review - Brazilian Journals Publicações de Periódicos e Editora Ltdafalse |
| dc.title.none.fl_str_mv |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| title |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| spellingShingle |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens Filho, Cloves Gomes de Carvalho Cambará Cerrado Endophytic fungus Vochysiaceae |
| title_short |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| title_full |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| title_fullStr |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| title_full_unstemmed |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| title_sort |
Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens/ Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens |
| author |
Filho, Cloves Gomes de Carvalho |
| author_facet |
Filho, Cloves Gomes de Carvalho Filho, Luis Claudio Kellner Picão, Bruno William Ragozoni, Arthur Alves Ribeiro, Arthur Barcelos Nicolella, Heloiza Diniz Squarisi, Iara Silva Soares, Marcos Antonio Tavares, Denise Crispim Silva, Marcio Luis Andrade e Cunha, Wilson Roberto Pauletti, Patricia Mendonça Januário, Ana Helena |
| author_role |
author |
| author2 |
Filho, Luis Claudio Kellner Picão, Bruno William Ragozoni, Arthur Alves Ribeiro, Arthur Barcelos Nicolella, Heloiza Diniz Squarisi, Iara Silva Soares, Marcos Antonio Tavares, Denise Crispim Silva, Marcio Luis Andrade e Cunha, Wilson Roberto Pauletti, Patricia Mendonça Januário, Ana Helena |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Filho, Cloves Gomes de Carvalho Filho, Luis Claudio Kellner Picão, Bruno William Ragozoni, Arthur Alves Ribeiro, Arthur Barcelos Nicolella, Heloiza Diniz Squarisi, Iara Silva Soares, Marcos Antonio Tavares, Denise Crispim Silva, Marcio Luis Andrade e Cunha, Wilson Roberto Pauletti, Patricia Mendonça Januário, Ana Helena |
| dc.subject.por.fl_str_mv |
Cambará Cerrado Endophytic fungus Vochysiaceae |
| topic |
Cambará Cerrado Endophytic fungus Vochysiaceae |
| description |
Chemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-04-24 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788 10.34115/basrv5n2-046 |
| url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788 |
| identifier_str_mv |
10.34115/basrv5n2-046 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/28788/22749 |
| dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Brazilian Applied Science Review info:eu-repo/semantics/openAccess |
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Copyright (c) 2021 Brazilian Applied Science Review |
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openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
| publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
| dc.source.none.fl_str_mv |
Brazilian Applied Science Review; Vol. 5 No. 2 (2021); 1244-1254 Brazilian Applied Science Review; v. 5 n. 2 (2021); 1244-1254 2595-3621 2595-3621 10.34115/basr.v5i2 reponame:Brazilian Applied Science Review instname:Brazilian Journals Publicações de Periódicos e Editora Ltda instacron:FIEP |
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Brazilian Journals Publicações de Periódicos e Editora Ltda |
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FIEP |
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FIEP |
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Brazilian Applied Science Review |
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Brazilian Applied Science Review |
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Brazilian Applied Science Review - Brazilian Journals Publicações de Periódicos e Editora Ltda |
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brazilianasr@yahoo.com || brazilianasr@yahoo.com |
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