Effect of Vitamin D supplementation on Systemic Lupus Erythematosus / Efeito da suplementação de Vitamina D no Lúpus Eritematoso Sistêmico

• Autor(a) principal: Siqueira, Adrielly Maria Duque de
• Data de Publicação: 2020
• Outros Autores: Souza, Pâmella Grasielle Vital Dias de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Health Review
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/20069
• topic: Doença Pulmonar Obstrutiva Crônica; Reabilitação; Teste de Caminhada de 6 minutos.

Autoimmune disorders are chronic diseases characterized by loss of tolerance of the immune system, resulting in major problems in the normal functioning of the body. Among the autoimmune diseases, systemic lupus erythematosus (SLE) has received a great deal of attention given the complexity of the disease, which affects multiple organs and tissues. Among existing treatments vitamin D supplementation is being considered as a new form of treatment given the effects that vitamin D has on the immune system. Vitamin D is well known for its effects on calcium regulation and its role in metabolic processes, but research has shown that this vitamin has a pluripotent effect on many systems, including immune cells. In this context, the present study aims to relate clinical and laboratory characteristics with the presence of vitamin D supplementation in these patients. This study allowed us to draw a clinical and laboratory profile of patients with SLE positive for vitamin D supplementation. Finally, this review provided a better direction of therapy for patients diagnosed with SLE through vitamin D supplementation. as well as demonstrating the importance of adequate serum vitamin D levels for humans, for the overall functioning of the body.