The production of mRNA vaccines in the COVID-19 pandemic: advent of new applications in health treatments

• Autor(a) principal: Silva, Ana Luiza Marques de Miranda
• Data de Publicação: 2023
• Outros Autores: de Araújo, Ana Paula Sales, Lima, Vitor Hugo Auzier, de Oliveira, Ciane Martins
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Health Review
• Texto Completo: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/60625
• topic: mRNA; vaccine technology; COVID-19; applications

Modern vaccines developed using mRNA technology are highly accurate formulations designed to stimulate the production of a variety of antigenic properties in the user in order to activate adaptive immunity. This enables the use of such technology in the research of vaccines against several infectious diseases, such as hepatitis C, Acquired Immunodeficiency Syndrome (AIDS), malaria, tuberculosis, in addition to chronic diseases, such as some types of cancer. Such vaccines were an efficient alternative in the fight against COVID-19 and have remarkable characteristics, such as the versatility of their applications and the ability to encode and express virtually any type of protein. Like this, this work is justified by the need to know the potential applications of this technology in clinical practice and in the search for effective alternative solutions in the fight against infectious and chronic diseases. A systematic review of the literature was carried out, including texts in Portuguese or English from 2019 to the present day and original texts published before 2019, searched in databases such as Science Direct, US National Library of Medicine, Scielo, Pubmed and Instituto Nacional de Industrial Property (INPI).