The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65703 |
Resumo: | The study aimed to evaluate the influence of invasion of the vas deferens and seminal vesicles in patients undergoing radical prostatectomy for stage T3b tumor on biochemical recurrence.Methods: Retrospective analysis of 53 patients submitted to radical prostatectomy with anatomopathological stage T3b, at Hospital de Clínicas da Unicamp, between 1997 and 2014. After exclusion criteria were applied, statistical analysis of 32 participants separated into 2 groups, in which 20 patients (62.5 %) without involvement of the vas deferens (group 1) and 12 (37.5%) with invasion of the vas deferens (group 2). Biochemical recurrence was defined as an increase in prostate specific antigen (PSA) greater than or equal to 0.2 ng/ml after surgery. Results: Regarding the disease-free survival analysis, group 2 has a 3.05 times greater risk of having a biochemical recurrence compared to group 1 (HR 3.05, 95% CI 1.12-8.32, p=0.03), calculated by regression of Cox and Log Rank test. Conclusion: In conclusion, this study has identified an elevated risk of biochemical recurrence in patients with both ductus deferens and seminal vesicle invasion. |
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Brazilian Journal of Health Review |
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The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomyvas deferensradical prostatectomybiochemical relapseThe study aimed to evaluate the influence of invasion of the vas deferens and seminal vesicles in patients undergoing radical prostatectomy for stage T3b tumor on biochemical recurrence.Methods: Retrospective analysis of 53 patients submitted to radical prostatectomy with anatomopathological stage T3b, at Hospital de Clínicas da Unicamp, between 1997 and 2014. After exclusion criteria were applied, statistical analysis of 32 participants separated into 2 groups, in which 20 patients (62.5 %) without involvement of the vas deferens (group 1) and 12 (37.5%) with invasion of the vas deferens (group 2). Biochemical recurrence was defined as an increase in prostate specific antigen (PSA) greater than or equal to 0.2 ng/ml after surgery. Results: Regarding the disease-free survival analysis, group 2 has a 3.05 times greater risk of having a biochemical recurrence compared to group 1 (HR 3.05, 95% CI 1.12-8.32, p=0.03), calculated by regression of Cox and Log Rank test. Conclusion: In conclusion, this study has identified an elevated risk of biochemical recurrence in patients with both ductus deferens and seminal vesicle invasion.Brazilian Journals Publicações de Periódicos e Editora Ltda.2023-12-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/6570310.34119/bjhrv6n6-427Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 32097-32105Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 32097-32105Brazilian Journal of Health Review; v. 6 n. 6 (2023); 32097-321052595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65703/47328Ottainano, Arthur DeganiFerruccio, Aline AkelMatheus, Marina BertoliniNaccarato, Angela Maria Elizabeth PiccolottoBillis, AthanaseFerreira, UbirajaraMatheus, Wagner Eduardoinfo:eu-repo/semantics/openAccess2024-01-15T18:54:30Zoai:ojs2.ojs.brazilianjournals.com.br:article/65703Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2024-01-15T18:54:30Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
title |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
spellingShingle |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy Ottainano, Arthur Degani vas deferens radical prostatectomy biochemical relapse |
title_short |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
title_full |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
title_fullStr |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
title_full_unstemmed |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
title_sort |
The impact of positive vas deferens in the biochemical relapse in patients with stage T3b prostate cancer submitted to radical Prostatectomy |
author |
Ottainano, Arthur Degani |
author_facet |
Ottainano, Arthur Degani Ferruccio, Aline Akel Matheus, Marina Bertolini Naccarato, Angela Maria Elizabeth Piccolotto Billis, Athanase Ferreira, Ubirajara Matheus, Wagner Eduardo |
author_role |
author |
author2 |
Ferruccio, Aline Akel Matheus, Marina Bertolini Naccarato, Angela Maria Elizabeth Piccolotto Billis, Athanase Ferreira, Ubirajara Matheus, Wagner Eduardo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Ottainano, Arthur Degani Ferruccio, Aline Akel Matheus, Marina Bertolini Naccarato, Angela Maria Elizabeth Piccolotto Billis, Athanase Ferreira, Ubirajara Matheus, Wagner Eduardo |
dc.subject.por.fl_str_mv |
vas deferens radical prostatectomy biochemical relapse |
topic |
vas deferens radical prostatectomy biochemical relapse |
description |
The study aimed to evaluate the influence of invasion of the vas deferens and seminal vesicles in patients undergoing radical prostatectomy for stage T3b tumor on biochemical recurrence.Methods: Retrospective analysis of 53 patients submitted to radical prostatectomy with anatomopathological stage T3b, at Hospital de Clínicas da Unicamp, between 1997 and 2014. After exclusion criteria were applied, statistical analysis of 32 participants separated into 2 groups, in which 20 patients (62.5 %) without involvement of the vas deferens (group 1) and 12 (37.5%) with invasion of the vas deferens (group 2). Biochemical recurrence was defined as an increase in prostate specific antigen (PSA) greater than or equal to 0.2 ng/ml after surgery. Results: Regarding the disease-free survival analysis, group 2 has a 3.05 times greater risk of having a biochemical recurrence compared to group 1 (HR 3.05, 95% CI 1.12-8.32, p=0.03), calculated by regression of Cox and Log Rank test. Conclusion: In conclusion, this study has identified an elevated risk of biochemical recurrence in patients with both ductus deferens and seminal vesicle invasion. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-12-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65703 10.34119/bjhrv6n6-427 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65703 |
identifier_str_mv |
10.34119/bjhrv6n6-427 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65703/47328 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 32097-32105 Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 32097-32105 Brazilian Journal of Health Review; v. 6 n. 6 (2023); 32097-32105 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
_version_ |
1797240039203143680 |