Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics
Autor(a) principal: | |
---|---|
Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Health Review |
Texto Completo: | https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65343 |
Resumo: | Aim: This research aimed to study the association of drug interactions and sociodemographic, clinical, and functional characteristics in nonagenarians in hyperpolypharmacy. Methods: This was a secondary analysis of an evaluation performed by the Multiprofessional Care for the Oldest-old Project in 2016, with participants identified in hyperpolypharmacy. Results: Results revealed that 69% of 29 participants had at least one major drug interaction, 41% had 10 or more moderate interactions, and 59% had minor interactions. The study revealed significant relationships for major drug interactions with the characteristics of recurrent urinary tract infections, anxiety, and palpitations. The study found near significance for white colour, not good general health and appetite, depression, and impaired cognition. For moderate drug interaction, findings showed a relationship near significance for females, perception of not good general health and appetite, hypertension, diabetes, urinary infection, depression scale change, agitation, pain, fatigue, and a fear of falling. For minor drug interactions, the study revealed significant findings for an association with depression, and apathy or sleepiness. There were findings near significance for an association with white colour, diabetes, agitation, pain, fatigue, and cough. Conclusion: Drug interactions are highly prevalent among nonagenarians in hyperpolypharmacy, with clinical and quality of life impact. Thus, they must be constantly evaluated for the presence of drug interactions at all levels of care, whether in primary care or in specialized care. A study with larger sample size and longitudinal contour is proposed to prove the importance of our observations. |
id |
BJRH-0_effb4d90415afc783b82cbbfd7eb9067 |
---|---|
oai_identifier_str |
oai:ojs2.ojs.brazilianjournals.com.br:article/65343 |
network_acronym_str |
BJRH-0 |
network_name_str |
Brazilian Journal of Health Review |
repository_id_str |
|
spelling |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristicspolymedication90+ years old peopleside-effectsquality of lifeAim: This research aimed to study the association of drug interactions and sociodemographic, clinical, and functional characteristics in nonagenarians in hyperpolypharmacy. Methods: This was a secondary analysis of an evaluation performed by the Multiprofessional Care for the Oldest-old Project in 2016, with participants identified in hyperpolypharmacy. Results: Results revealed that 69% of 29 participants had at least one major drug interaction, 41% had 10 or more moderate interactions, and 59% had minor interactions. The study revealed significant relationships for major drug interactions with the characteristics of recurrent urinary tract infections, anxiety, and palpitations. The study found near significance for white colour, not good general health and appetite, depression, and impaired cognition. For moderate drug interaction, findings showed a relationship near significance for females, perception of not good general health and appetite, hypertension, diabetes, urinary infection, depression scale change, agitation, pain, fatigue, and a fear of falling. For minor drug interactions, the study revealed significant findings for an association with depression, and apathy or sleepiness. There were findings near significance for an association with white colour, diabetes, agitation, pain, fatigue, and cough. Conclusion: Drug interactions are highly prevalent among nonagenarians in hyperpolypharmacy, with clinical and quality of life impact. Thus, they must be constantly evaluated for the presence of drug interactions at all levels of care, whether in primary care or in specialized care. A study with larger sample size and longitudinal contour is proposed to prove the importance of our observations.Brazilian Journals Publicações de Periódicos e Editora Ltda.2023-12-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/6534310.34119/bjhrv6n6-305Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 30543-30555Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 30543-30555Brazilian Journal of Health Review; v. 6 n. 6 (2023); 30543-305552595-6825reponame:Brazilian Journal of Health Reviewinstname:Federação das Indústrias do Estado do Paraná (FIEP)instacron:BJRHenghttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65343/46709Rubert, Viviane MauraRiva, Alice Motta DallaSoares, Carolina BoeiraWeber, Eduarda KotlinskyBenvegnu, Giovana BreitenbachEilers, Isadora SouzaMoroni, Luisa Lehrde Fraga, Viviane CardosoZawislak, Rafael BraccioEly, Mariana Graeff Binsde Ros, Luisa Vitoria PontaltiDanzmann, LeticiaVelho, Isabella Knorre Silva, Fernanda Mambrini SoRadin, VanessaGilbert, BethanyMorgan, TracieBós, Angelo Jose Gonçalvesinfo:eu-repo/semantics/openAccess2023-12-07T17:15:02Zoai:ojs2.ojs.brazilianjournals.com.br:article/65343Revistahttp://www.brazilianjournals.com/index.php/BJHR/indexPRIhttps://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/oai|| brazilianjhr@gmail.com2595-68252595-6825opendoar:2023-12-07T17:15:02Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP)false |
dc.title.none.fl_str_mv |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
title |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
spellingShingle |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics Rubert, Viviane Maura polymedication 90+ years old people side-effects quality of life |
title_short |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
title_full |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
title_fullStr |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
title_full_unstemmed |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
title_sort |
Nonagenarians in Hyperpolypharmacy: relationship between the level of drug interactions and sociodemographic, clinical, and functional characteristics |
author |
Rubert, Viviane Maura |
author_facet |
Rubert, Viviane Maura Riva, Alice Motta Dalla Soares, Carolina Boeira Weber, Eduarda Kotlinsky Benvegnu, Giovana Breitenbach Eilers, Isadora Souza Moroni, Luisa Lehr de Fraga, Viviane Cardoso Zawislak, Rafael Braccio Ely, Mariana Graeff Bins de Ros, Luisa Vitoria Pontalti Danzmann, Leticia Velho, Isabella Knorr e Silva, Fernanda Mambrini So Radin, Vanessa Gilbert, Bethany Morgan, Tracie Bós, Angelo Jose Gonçalves |
author_role |
author |
author2 |
Riva, Alice Motta Dalla Soares, Carolina Boeira Weber, Eduarda Kotlinsky Benvegnu, Giovana Breitenbach Eilers, Isadora Souza Moroni, Luisa Lehr de Fraga, Viviane Cardoso Zawislak, Rafael Braccio Ely, Mariana Graeff Bins de Ros, Luisa Vitoria Pontalti Danzmann, Leticia Velho, Isabella Knorr e Silva, Fernanda Mambrini So Radin, Vanessa Gilbert, Bethany Morgan, Tracie Bós, Angelo Jose Gonçalves |
author2_role |
author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Rubert, Viviane Maura Riva, Alice Motta Dalla Soares, Carolina Boeira Weber, Eduarda Kotlinsky Benvegnu, Giovana Breitenbach Eilers, Isadora Souza Moroni, Luisa Lehr de Fraga, Viviane Cardoso Zawislak, Rafael Braccio Ely, Mariana Graeff Bins de Ros, Luisa Vitoria Pontalti Danzmann, Leticia Velho, Isabella Knorr e Silva, Fernanda Mambrini So Radin, Vanessa Gilbert, Bethany Morgan, Tracie Bós, Angelo Jose Gonçalves |
dc.subject.por.fl_str_mv |
polymedication 90+ years old people side-effects quality of life |
topic |
polymedication 90+ years old people side-effects quality of life |
description |
Aim: This research aimed to study the association of drug interactions and sociodemographic, clinical, and functional characteristics in nonagenarians in hyperpolypharmacy. Methods: This was a secondary analysis of an evaluation performed by the Multiprofessional Care for the Oldest-old Project in 2016, with participants identified in hyperpolypharmacy. Results: Results revealed that 69% of 29 participants had at least one major drug interaction, 41% had 10 or more moderate interactions, and 59% had minor interactions. The study revealed significant relationships for major drug interactions with the characteristics of recurrent urinary tract infections, anxiety, and palpitations. The study found near significance for white colour, not good general health and appetite, depression, and impaired cognition. For moderate drug interaction, findings showed a relationship near significance for females, perception of not good general health and appetite, hypertension, diabetes, urinary infection, depression scale change, agitation, pain, fatigue, and a fear of falling. For minor drug interactions, the study revealed significant findings for an association with depression, and apathy or sleepiness. There were findings near significance for an association with white colour, diabetes, agitation, pain, fatigue, and cough. Conclusion: Drug interactions are highly prevalent among nonagenarians in hyperpolypharmacy, with clinical and quality of life impact. Thus, they must be constantly evaluated for the presence of drug interactions at all levels of care, whether in primary care or in specialized care. A study with larger sample size and longitudinal contour is proposed to prove the importance of our observations. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-12-05 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65343 10.34119/bjhrv6n6-305 |
url |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65343 |
identifier_str_mv |
10.34119/bjhrv6n6-305 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/65343/46709 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
publisher.none.fl_str_mv |
Brazilian Journals Publicações de Periódicos e Editora Ltda. |
dc.source.none.fl_str_mv |
Brazilian Journal of Health Review; Vol. 6 No. 6 (2023); 30543-30555 Brazilian Journal of Health Review; Vol. 6 Núm. 6 (2023); 30543-30555 Brazilian Journal of Health Review; v. 6 n. 6 (2023); 30543-30555 2595-6825 reponame:Brazilian Journal of Health Review instname:Federação das Indústrias do Estado do Paraná (FIEP) instacron:BJRH |
instname_str |
Federação das Indústrias do Estado do Paraná (FIEP) |
instacron_str |
BJRH |
institution |
BJRH |
reponame_str |
Brazilian Journal of Health Review |
collection |
Brazilian Journal of Health Review |
repository.name.fl_str_mv |
Brazilian Journal of Health Review - Federação das Indústrias do Estado do Paraná (FIEP) |
repository.mail.fl_str_mv |
|| brazilianjhr@gmail.com |
_version_ |
1797240038668369920 |