Use of antibacterial agents in an intensive care unit in a hospital in Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000300011 |
Resumo: | It is essential to monitor the utilisation of antibacterial drugs in order to establish appropriate measures for their control. The pattern of usage of antibacterial drugs, and its association with indicators of hospital infection, has been investigated in a non-specialized adult intensive care unit (ICU) located in Santa Luzia Hospital (Brasília, DF, Brazil). The study was conducted between January 2001 and June 2004. Data concerning the utilisation of systemic antibacterial drugs, classified according to the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) system, and indicators of hospital infection, defined according to the National Nosocomial Infections Surveillance (NNIS) system, were obtained from appropriate hospital archives. During the study period, the average utilisation of antibacterial drugs was 1918.5 DDD units per 1000 patient-day (DDD1000). The three most used drugs were penicillins/beta-lactamase inhibitors (535.3 DDD1000), third generation cephalosporins (239.1 DDD1000) and quinolones (212.5 DDD1000). The total utilisation of antibacterial drugs was correlated significantly with the incidence of hospital infection (R = 0.62; p < 0.01) and the index of invasive procedures (R = 0.41; p < 0.01). Furthermore, the latter two indicators were significantly and positively correlated with the use of recently commercialised, broad spectrum antibacterial drugs (except for carbapenems). It is concluded that improved infection control procedures, together with more rigorous criteria regarding the use of invasive procedures, should be implemented by the ICU studied in order to diminish the utilisation of antibacterial drugs. |
id |
BSID-1_1fac1515ec65b1430821864f10fd0f73 |
---|---|
oai_identifier_str |
oai:scielo:S1413-86702007000300011 |
network_acronym_str |
BSID-1 |
network_name_str |
Brazilian Journal of Infectious Diseases |
repository_id_str |
|
spelling |
Use of antibacterial agents in an intensive care unit in a hospital in BrazilAntibacterial drugsintensive care unithospital infectionsinvasive practicesIt is essential to monitor the utilisation of antibacterial drugs in order to establish appropriate measures for their control. The pattern of usage of antibacterial drugs, and its association with indicators of hospital infection, has been investigated in a non-specialized adult intensive care unit (ICU) located in Santa Luzia Hospital (Brasília, DF, Brazil). The study was conducted between January 2001 and June 2004. Data concerning the utilisation of systemic antibacterial drugs, classified according to the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) system, and indicators of hospital infection, defined according to the National Nosocomial Infections Surveillance (NNIS) system, were obtained from appropriate hospital archives. During the study period, the average utilisation of antibacterial drugs was 1918.5 DDD units per 1000 patient-day (DDD1000). The three most used drugs were penicillins/beta-lactamase inhibitors (535.3 DDD1000), third generation cephalosporins (239.1 DDD1000) and quinolones (212.5 DDD1000). The total utilisation of antibacterial drugs was correlated significantly with the incidence of hospital infection (R = 0.62; p < 0.01) and the index of invasive procedures (R = 0.41; p < 0.01). Furthermore, the latter two indicators were significantly and positively correlated with the use of recently commercialised, broad spectrum antibacterial drugs (except for carbapenems). It is concluded that improved infection control procedures, together with more rigorous criteria regarding the use of invasive procedures, should be implemented by the ICU studied in order to diminish the utilisation of antibacterial drugs.Brazilian Society of Infectious Diseases2007-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000300011Brazilian Journal of Infectious Diseases v.11 n.3 2007reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702007000300011info:eu-repo/semantics/openAccessSantos,E.F. dosLauria-Pires,L.Pereira,M.G.Silva,A.E.Rodrigues,I.P.Maia,M.O.eng2007-07-30T00:00:00Zoai:scielo:S1413-86702007000300011Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2007-07-30T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
title |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
spellingShingle |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil Santos,E.F. dos Antibacterial drugs intensive care unit hospital infections invasive practices |
title_short |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
title_full |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
title_fullStr |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
title_full_unstemmed |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
title_sort |
Use of antibacterial agents in an intensive care unit in a hospital in Brazil |
author |
Santos,E.F. dos |
author_facet |
Santos,E.F. dos Lauria-Pires,L. Pereira,M.G. Silva,A.E. Rodrigues,I.P. Maia,M.O. |
author_role |
author |
author2 |
Lauria-Pires,L. Pereira,M.G. Silva,A.E. Rodrigues,I.P. Maia,M.O. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Santos,E.F. dos Lauria-Pires,L. Pereira,M.G. Silva,A.E. Rodrigues,I.P. Maia,M.O. |
dc.subject.por.fl_str_mv |
Antibacterial drugs intensive care unit hospital infections invasive practices |
topic |
Antibacterial drugs intensive care unit hospital infections invasive practices |
description |
It is essential to monitor the utilisation of antibacterial drugs in order to establish appropriate measures for their control. The pattern of usage of antibacterial drugs, and its association with indicators of hospital infection, has been investigated in a non-specialized adult intensive care unit (ICU) located in Santa Luzia Hospital (Brasília, DF, Brazil). The study was conducted between January 2001 and June 2004. Data concerning the utilisation of systemic antibacterial drugs, classified according to the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) system, and indicators of hospital infection, defined according to the National Nosocomial Infections Surveillance (NNIS) system, were obtained from appropriate hospital archives. During the study period, the average utilisation of antibacterial drugs was 1918.5 DDD units per 1000 patient-day (DDD1000). The three most used drugs were penicillins/beta-lactamase inhibitors (535.3 DDD1000), third generation cephalosporins (239.1 DDD1000) and quinolones (212.5 DDD1000). The total utilisation of antibacterial drugs was correlated significantly with the incidence of hospital infection (R = 0.62; p < 0.01) and the index of invasive procedures (R = 0.41; p < 0.01). Furthermore, the latter two indicators were significantly and positively correlated with the use of recently commercialised, broad spectrum antibacterial drugs (except for carbapenems). It is concluded that improved infection control procedures, together with more rigorous criteria regarding the use of invasive procedures, should be implemented by the ICU studied in order to diminish the utilisation of antibacterial drugs. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000300011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000300011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1413-86702007000300011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.11 n.3 2007 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
_version_ |
1754209239870472192 |