Modulation of cerebral malaria by curcumin as an adjunctive therapy
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500011 |
Resumo: | Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits. |
id |
BSID-1_253d1f8282897b83a45be6c87ed2aa3a |
---|---|
oai_identifier_str |
oai:scielo:S1413-86702013000500011 |
network_acronym_str |
BSID-1 |
network_name_str |
Brazilian Journal of Infectious Diseases |
repository_id_str |
|
spelling |
Modulation of cerebral malaria by curcumin as an adjunctive therapyCerebral malariaCurcuminAdjunctiveCognitive deficitCerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits.Brazilian Society of Infectious Diseases2013-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500011Brazilian Journal of Infectious Diseases v.17 n.5 2013reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1016/j.bjid.2013.03.004info:eu-repo/semantics/openAccessJain,KunalSood,SumeetGowthamarajan,K.eng2013-10-21T00:00:00Zoai:scielo:S1413-86702013000500011Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2013-10-21T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
title |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
spellingShingle |
Modulation of cerebral malaria by curcumin as an adjunctive therapy Jain,Kunal Cerebral malaria Curcumin Adjunctive Cognitive deficit |
title_short |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
title_full |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
title_fullStr |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
title_full_unstemmed |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
title_sort |
Modulation of cerebral malaria by curcumin as an adjunctive therapy |
author |
Jain,Kunal |
author_facet |
Jain,Kunal Sood,Sumeet Gowthamarajan,K. |
author_role |
author |
author2 |
Sood,Sumeet Gowthamarajan,K. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Jain,Kunal Sood,Sumeet Gowthamarajan,K. |
dc.subject.por.fl_str_mv |
Cerebral malaria Curcumin Adjunctive Cognitive deficit |
topic |
Cerebral malaria Curcumin Adjunctive Cognitive deficit |
description |
Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjid.2013.03.004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.17 n.5 2013 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
_version_ |
1754209242771881984 |