Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study

Detalhes bibliográficos
Autor(a) principal: Brites,Carlos
Data de Publicação: 2006
Outros Autores: Silva,Nanci, Sampaio- Sá,Márcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400003
Resumo: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become an increasing problem in Brazilian hospitals within the last years. In Bahia, there is scarce information on the epidemiological characteristics of MRSA infections and their determinants. The objective of this study was to evaluate the temporal evolution of MRSA infections in a private, tertiary hospital, in Salvador, the capital of the state of Bahia. We reviewed the microbiological records of bacterial isolates from the Hospital Espanhol, a 300 bed, general hospital, in Salvador. We analyzed the frequency of positive cultures for S. aureus during the last nine years, the prevalence of MRSA, and the spatial distribution of the isolates in the hospital. We also evaluated the temporal evolution of MRSA during the study period. Seven-hundred-ten cultures were positive for S. aureus from 1996 through 2004. The prevalence of MRSA was 28%. The intensive care unit (59%), the hemodyalisis unit (43%), and the infectious diseases unit (34%) presented with significantly higher prevalence of MRSA, when compared to the remaining clinics of the hospital. We detected a significant increase of MRSA isolation among patients with nosocomial infections, over time (P<0.0001). MRSA isolates were highly resistant to alternative drugs (clyndamicin, erythromycin, co-trimexazole, levofloxacin), reinforcing the likelihood of nosocomial acquisition of the pathogen. The overall prevalence of MRSA in the hospital has remained relatively stable within the last nine years, but there was a significant trend forincreasing nosocomial acquisition of MRSA over time, which is even higher for patients attended in intensive care units, HDU, or IDU.
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spelling Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation studyStaphylococcus aureusMRSAbacterial resistanceInfections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become an increasing problem in Brazilian hospitals within the last years. In Bahia, there is scarce information on the epidemiological characteristics of MRSA infections and their determinants. The objective of this study was to evaluate the temporal evolution of MRSA infections in a private, tertiary hospital, in Salvador, the capital of the state of Bahia. We reviewed the microbiological records of bacterial isolates from the Hospital Espanhol, a 300 bed, general hospital, in Salvador. We analyzed the frequency of positive cultures for S. aureus during the last nine years, the prevalence of MRSA, and the spatial distribution of the isolates in the hospital. We also evaluated the temporal evolution of MRSA during the study period. Seven-hundred-ten cultures were positive for S. aureus from 1996 through 2004. The prevalence of MRSA was 28%. The intensive care unit (59%), the hemodyalisis unit (43%), and the infectious diseases unit (34%) presented with significantly higher prevalence of MRSA, when compared to the remaining clinics of the hospital. We detected a significant increase of MRSA isolation among patients with nosocomial infections, over time (P<0.0001). MRSA isolates were highly resistant to alternative drugs (clyndamicin, erythromycin, co-trimexazole, levofloxacin), reinforcing the likelihood of nosocomial acquisition of the pathogen. The overall prevalence of MRSA in the hospital has remained relatively stable within the last nine years, but there was a significant trend forincreasing nosocomial acquisition of MRSA over time, which is even higher for patients attended in intensive care units, HDU, or IDU.Brazilian Society of Infectious Diseases2006-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400003Brazilian Journal of Infectious Diseases v.10 n.4 2006reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702006000400003info:eu-repo/semantics/openAccessBrites,CarlosSilva,NanciSampaio- Sá,Márciaeng2007-02-02T00:00:00Zoai:scielo:S1413-86702006000400003Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2007-02-02T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
title Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
spellingShingle Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
Brites,Carlos
Staphylococcus aureus
MRSA
bacterial resistance
title_short Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
title_full Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
title_fullStr Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
title_full_unstemmed Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
title_sort Temporal evolution of the prevalence of methicillin-resistant Staphylococcus aureus in a tertiary hospital in Bahia, Brazil: a nine-year evaluation study
author Brites,Carlos
author_facet Brites,Carlos
Silva,Nanci
Sampaio- Sá,Márcia
author_role author
author2 Silva,Nanci
Sampaio- Sá,Márcia
author2_role author
author
dc.contributor.author.fl_str_mv Brites,Carlos
Silva,Nanci
Sampaio- Sá,Márcia
dc.subject.por.fl_str_mv Staphylococcus aureus
MRSA
bacterial resistance
topic Staphylococcus aureus
MRSA
bacterial resistance
description Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become an increasing problem in Brazilian hospitals within the last years. In Bahia, there is scarce information on the epidemiological characteristics of MRSA infections and their determinants. The objective of this study was to evaluate the temporal evolution of MRSA infections in a private, tertiary hospital, in Salvador, the capital of the state of Bahia. We reviewed the microbiological records of bacterial isolates from the Hospital Espanhol, a 300 bed, general hospital, in Salvador. We analyzed the frequency of positive cultures for S. aureus during the last nine years, the prevalence of MRSA, and the spatial distribution of the isolates in the hospital. We also evaluated the temporal evolution of MRSA during the study period. Seven-hundred-ten cultures were positive for S. aureus from 1996 through 2004. The prevalence of MRSA was 28%. The intensive care unit (59%), the hemodyalisis unit (43%), and the infectious diseases unit (34%) presented with significantly higher prevalence of MRSA, when compared to the remaining clinics of the hospital. We detected a significant increase of MRSA isolation among patients with nosocomial infections, over time (P<0.0001). MRSA isolates were highly resistant to alternative drugs (clyndamicin, erythromycin, co-trimexazole, levofloxacin), reinforcing the likelihood of nosocomial acquisition of the pathogen. The overall prevalence of MRSA in the hospital has remained relatively stable within the last nine years, but there was a significant trend forincreasing nosocomial acquisition of MRSA over time, which is even higher for patients attended in intensive care units, HDU, or IDU.
publishDate 2006
dc.date.none.fl_str_mv 2006-08-01
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dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.10 n.4 2006
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
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collection Brazilian Journal of Infectious Diseases
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