Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines

Detalhes bibliográficos
Autor(a) principal: Fallah,Shahrzad
Data de Publicação: 2011
Outros Autores: Tabatabaei,Ahmad, Pournasir,Zahra, Chavoshzadeh,Zahra, Rezaei,Nima
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500013
Resumo: Cytomegalovirus (CMV) infection is a common opportunistic systemic infection in immunocompromised patients, but skin involvement is rare. Herein, we report a 10 year-old girl from consanguineous parents who was referred to our center because of disseminated maculopapular rash. She had history of upper and lower respiratory tract infections. In immunological studies, increased serum IgE level and decreased responses to tetanus and diphtheria were detected. Polymerase chain reaction (PCR) examination of bronchoalveolar lavage and serum sample revealed the presence of CMV. Early diagnosis of cutaneous CMV and appropriate treatment are the key actions in management of patients with underlying immunodeficiencies to avoid further complications.
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spelling Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccinescytomegalovirus infectionsantibody formationcommon variable immunodeficiencyCytomegalovirus (CMV) infection is a common opportunistic systemic infection in immunocompromised patients, but skin involvement is rare. Herein, we report a 10 year-old girl from consanguineous parents who was referred to our center because of disseminated maculopapular rash. She had history of upper and lower respiratory tract infections. In immunological studies, increased serum IgE level and decreased responses to tetanus and diphtheria were detected. Polymerase chain reaction (PCR) examination of bronchoalveolar lavage and serum sample revealed the presence of CMV. Early diagnosis of cutaneous CMV and appropriate treatment are the key actions in management of patients with underlying immunodeficiencies to avoid further complications.Brazilian Society of Infectious Diseases2011-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500013Brazilian Journal of Infectious Diseases v.15 n.5 2011reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702011000500013info:eu-repo/semantics/openAccessFallah,ShahrzadTabatabaei,AhmadPournasir,ZahraChavoshzadeh,ZahraRezaei,Nimaeng2011-10-17T00:00:00Zoai:scielo:S1413-86702011000500013Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2011-10-17T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
title Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
spellingShingle Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
Fallah,Shahrzad
cytomegalovirus infections
antibody formation
common variable immunodeficiency
title_short Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
title_full Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
title_fullStr Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
title_full_unstemmed Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
title_sort Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines
author Fallah,Shahrzad
author_facet Fallah,Shahrzad
Tabatabaei,Ahmad
Pournasir,Zahra
Chavoshzadeh,Zahra
Rezaei,Nima
author_role author
author2 Tabatabaei,Ahmad
Pournasir,Zahra
Chavoshzadeh,Zahra
Rezaei,Nima
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Fallah,Shahrzad
Tabatabaei,Ahmad
Pournasir,Zahra
Chavoshzadeh,Zahra
Rezaei,Nima
dc.subject.por.fl_str_mv cytomegalovirus infections
antibody formation
common variable immunodeficiency
topic cytomegalovirus infections
antibody formation
common variable immunodeficiency
description Cytomegalovirus (CMV) infection is a common opportunistic systemic infection in immunocompromised patients, but skin involvement is rare. Herein, we report a 10 year-old girl from consanguineous parents who was referred to our center because of disseminated maculopapular rash. She had history of upper and lower respiratory tract infections. In immunological studies, increased serum IgE level and decreased responses to tetanus and diphtheria were detected. Polymerase chain reaction (PCR) examination of bronchoalveolar lavage and serum sample revealed the presence of CMV. Early diagnosis of cutaneous CMV and appropriate treatment are the key actions in management of patients with underlying immunodeficiencies to avoid further complications.
publishDate 2011
dc.date.none.fl_str_mv 2011-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1413-86702011000500013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.15 n.5 2011
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
instname_str Brazilian Society of Infectious Diseases (BSID)
instacron_str BSID
institution BSID
reponame_str Brazilian Journal of Infectious Diseases
collection Brazilian Journal of Infectious Diseases
repository.name.fl_str_mv Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)
repository.mail.fl_str_mv bjid@bjid.org.br||lgoldani@ufrgs.br
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