Bilateral afrenal nodules due to histoplasmosis in an elderly

• Autor(a) principal: Carvalho,Flávio Pedreira de Freitas de
• Data de Publicação: 2007
• Outros Autores: Curiati,José Antônio Esper, Mauad,Thaís, Incerti,Milena Mendes, Jacob Filho,Wilson
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Brazilian Journal of Infectious Diseases
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000100033
• topic: Histoplasmosis; adrenal nodule; Addison disease; elderly; Histoplasma capsulatum

We report a case history of an 84-year-old elderly male patient that presented with a clinical picture suggestive of adrenal failure and bilateral adrenal nodules detected by abdominal computed tomography. A fine needle-guided biopsy was inconclusive for achieving a final diagnosis. The patient died due to septic shock and the autopsy disclosed histoplasmosis with extensive bilateral necrosis of the adrenal glands. Although the adrenal involvement in chronic disseminated histoplasmosis has been described, there have been few reports of the infection being associated with adrenal insufficiency.