Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600006 |
Resumo: | OBJECTIVE: To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality. METHODS: Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis. RESULTS: Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95% confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively). CONCLUSION: The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings. |
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Brazilian Journal of Infectious Diseases |
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Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis studyChlamydia trachomatisperinatal mortalitymorbiditymeta-analysisOBJECTIVE: To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality. METHODS: Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis. RESULTS: Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95% confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively). CONCLUSION: The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings.Brazilian Society of Infectious Diseases2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600006Brazilian Journal of Infectious Diseases v.15 n.6 2011reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702011000600006info:eu-repo/semantics/openAccessSilva,Maria José Penna Maisonnette de AttaydeFlorêncio,Gilzandra Lira DantasGabiatti,José Roberto ErbolatoAmaral,Rose Luce doEleutério Júnior,JoséGonçalves,Ana Katherine da Silveiraeng2012-01-04T00:00:00Zoai:scielo:S1413-86702011000600006Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2012-01-04T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
title |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
spellingShingle |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study Silva,Maria José Penna Maisonnette de Attayde Chlamydia trachomatis perinatal mortality morbidity meta-analysis |
title_short |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
title_full |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
title_fullStr |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
title_full_unstemmed |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
title_sort |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study |
author |
Silva,Maria José Penna Maisonnette de Attayde |
author_facet |
Silva,Maria José Penna Maisonnette de Attayde Florêncio,Gilzandra Lira Dantas Gabiatti,José Roberto Erbolato Amaral,Rose Luce do Eleutério Júnior,José Gonçalves,Ana Katherine da Silveira |
author_role |
author |
author2 |
Florêncio,Gilzandra Lira Dantas Gabiatti,José Roberto Erbolato Amaral,Rose Luce do Eleutério Júnior,José Gonçalves,Ana Katherine da Silveira |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Silva,Maria José Penna Maisonnette de Attayde Florêncio,Gilzandra Lira Dantas Gabiatti,José Roberto Erbolato Amaral,Rose Luce do Eleutério Júnior,José Gonçalves,Ana Katherine da Silveira |
dc.subject.por.fl_str_mv |
Chlamydia trachomatis perinatal mortality morbidity meta-analysis |
topic |
Chlamydia trachomatis perinatal mortality morbidity meta-analysis |
description |
OBJECTIVE: To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality. METHODS: Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis. RESULTS: Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95% confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively). CONCLUSION: The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600006 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1413-86702011000600006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.15 n.6 2011 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
_version_ |
1754209241966575616 |