Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014 |
Resumo: | INTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. CONCLUSION: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet. |
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Risk factors related to hypertension among patients in a cohort living with HIV/AIDSHIV/AIDShypertensionantiretroviral therapycardiovascular riskINTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. CONCLUSION: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet.Brazilian Society of Infectious Diseases2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014Brazilian Journal of Infectious Diseases v.14 n.3 2010reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702010000300014info:eu-repo/semantics/openAccessArruda Junior,Evanizio Roque deLacerda,Heloisa RamosMoura,Libia Cristina Rocha VilelaAlbuquerque,Maria de Fatima Pessoa Militão deMiranda Filho,Democrito de BarrosDiniz,George Tadeu NunesAlbuquerque,Valeria Maria Gonçalves deAmaral,Josefina Cláudia ZirpoliXimenes,Ricardo Alencar de ArraesMonteiro,Verônica Soareseng2010-09-03T00:00:00Zoai:scielo:S1413-86702010000300014Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2010-09-03T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
title |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
spellingShingle |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS Arruda Junior,Evanizio Roque de HIV/AIDS hypertension antiretroviral therapy cardiovascular risk |
title_short |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
title_full |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
title_fullStr |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
title_full_unstemmed |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
title_sort |
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS |
author |
Arruda Junior,Evanizio Roque de |
author_facet |
Arruda Junior,Evanizio Roque de Lacerda,Heloisa Ramos Moura,Libia Cristina Rocha Vilela Albuquerque,Maria de Fatima Pessoa Militão de Miranda Filho,Democrito de Barros Diniz,George Tadeu Nunes Albuquerque,Valeria Maria Gonçalves de Amaral,Josefina Cláudia Zirpoli Ximenes,Ricardo Alencar de Arraes Monteiro,Verônica Soares |
author_role |
author |
author2 |
Lacerda,Heloisa Ramos Moura,Libia Cristina Rocha Vilela Albuquerque,Maria de Fatima Pessoa Militão de Miranda Filho,Democrito de Barros Diniz,George Tadeu Nunes Albuquerque,Valeria Maria Gonçalves de Amaral,Josefina Cláudia Zirpoli Ximenes,Ricardo Alencar de Arraes Monteiro,Verônica Soares |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Arruda Junior,Evanizio Roque de Lacerda,Heloisa Ramos Moura,Libia Cristina Rocha Vilela Albuquerque,Maria de Fatima Pessoa Militão de Miranda Filho,Democrito de Barros Diniz,George Tadeu Nunes Albuquerque,Valeria Maria Gonçalves de Amaral,Josefina Cláudia Zirpoli Ximenes,Ricardo Alencar de Arraes Monteiro,Verônica Soares |
dc.subject.por.fl_str_mv |
HIV/AIDS hypertension antiretroviral therapy cardiovascular risk |
topic |
HIV/AIDS hypertension antiretroviral therapy cardiovascular risk |
description |
INTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. CONCLUSION: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1413-86702010000300014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.14 n.3 2010 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
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1754209241176997888 |