Risk factors related to hypertension among patients in a cohort living with HIV/AIDS

Detalhes bibliográficos
Autor(a) principal: Arruda Junior,Evanizio Roque de
Data de Publicação: 2010
Outros Autores: Lacerda,Heloisa Ramos, Moura,Libia Cristina Rocha Vilela, Albuquerque,Maria de Fatima Pessoa Militão de, Miranda Filho,Democrito de Barros, Diniz,George Tadeu Nunes, Albuquerque,Valeria Maria Gonçalves de, Amaral,Josefina Cláudia Zirpoli, Ximenes,Ricardo Alencar de Arraes, Monteiro,Verônica Soares
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014
Resumo: INTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. CONCLUSION: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet.
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spelling Risk factors related to hypertension among patients in a cohort living with HIV/AIDSHIV/AIDShypertensionantiretroviral therapycardiovascular riskINTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. CONCLUSION: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet.Brazilian Society of Infectious Diseases2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014Brazilian Journal of Infectious Diseases v.14 n.3 2010reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702010000300014info:eu-repo/semantics/openAccessArruda Junior,Evanizio Roque deLacerda,Heloisa RamosMoura,Libia Cristina Rocha VilelaAlbuquerque,Maria de Fatima Pessoa Militão deMiranda Filho,Democrito de BarrosDiniz,George Tadeu NunesAlbuquerque,Valeria Maria Gonçalves deAmaral,Josefina Cláudia ZirpoliXimenes,Ricardo Alencar de ArraesMonteiro,Verônica Soareseng2010-09-03T00:00:00Zoai:scielo:S1413-86702010000300014Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2010-09-03T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
title Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
spellingShingle Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
Arruda Junior,Evanizio Roque de
HIV/AIDS
hypertension
antiretroviral therapy
cardiovascular risk
title_short Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
title_full Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
title_fullStr Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
title_full_unstemmed Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
title_sort Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
author Arruda Junior,Evanizio Roque de
author_facet Arruda Junior,Evanizio Roque de
Lacerda,Heloisa Ramos
Moura,Libia Cristina Rocha Vilela
Albuquerque,Maria de Fatima Pessoa Militão de
Miranda Filho,Democrito de Barros
Diniz,George Tadeu Nunes
Albuquerque,Valeria Maria Gonçalves de
Amaral,Josefina Cláudia Zirpoli
Ximenes,Ricardo Alencar de Arraes
Monteiro,Verônica Soares
author_role author
author2 Lacerda,Heloisa Ramos
Moura,Libia Cristina Rocha Vilela
Albuquerque,Maria de Fatima Pessoa Militão de
Miranda Filho,Democrito de Barros
Diniz,George Tadeu Nunes
Albuquerque,Valeria Maria Gonçalves de
Amaral,Josefina Cláudia Zirpoli
Ximenes,Ricardo Alencar de Arraes
Monteiro,Verônica Soares
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Arruda Junior,Evanizio Roque de
Lacerda,Heloisa Ramos
Moura,Libia Cristina Rocha Vilela
Albuquerque,Maria de Fatima Pessoa Militão de
Miranda Filho,Democrito de Barros
Diniz,George Tadeu Nunes
Albuquerque,Valeria Maria Gonçalves de
Amaral,Josefina Cláudia Zirpoli
Ximenes,Ricardo Alencar de Arraes
Monteiro,Verônica Soares
dc.subject.por.fl_str_mv HIV/AIDS
hypertension
antiretroviral therapy
cardiovascular risk
topic HIV/AIDS
hypertension
antiretroviral therapy
cardiovascular risk
description INTRODUCTION: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. OBJECTIVE: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. METHOD: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. RESULTS: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. CONCLUSION: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet.
publishDate 2010
dc.date.none.fl_str_mv 2010-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000300014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1413-86702010000300014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.14 n.3 2010
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
instname_str Brazilian Society of Infectious Diseases (BSID)
instacron_str BSID
institution BSID
reponame_str Brazilian Journal of Infectious Diseases
collection Brazilian Journal of Infectious Diseases
repository.name.fl_str_mv Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)
repository.mail.fl_str_mv bjid@bjid.org.br||lgoldani@ufrgs.br
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