Does sensitization by SARS-CoV-2 immune complexes trigger DRESS syndrome?

• Autor(a) principal: Cruz,Virgínia Barbeitos
• Data de Publicação: 2022
• Outros Autores: Fleury Júnior,Luiz Fernando Fróes, Kobal,Christiane Reis, da Silva,Nilzio Antonio
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Brazilian Journal of Infectious Diseases
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702022000200401
• topic: COVID-19; SARS-CoV-2; Exanthema; Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome

Abstract The diagnosis of coronavirus disease (COVID-19) has been a great challenge since the infection affects not only the respiratory system, but also different organs, given the intense inflammatory and autoimmune reaction triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Herein we present a case of a 36-year-old male patient, with some comorbidities and previous use of carbamazepine, who developed a severe condition triggered by COVID-19, including extensive exfoliative erythroderma and severe impairment of liver function, which lasted approximately 80 days.