Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil

Detalhes bibliográficos
Autor(a) principal: Nagaya,Leonardo Hideto
Data de Publicação: 2017
Outros Autores: Salles,Mauro José Costa, Takikawa,Lucas Sadawo Chagas, Fregoneze,Marcelo, Doneux,Pedro, Silva,Luciana Andrade da, Sella,Guilherme do Val, Miyazaki,Alberto Naoki, Checchia,Sergio Luiz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600613
Resumo: ABSTRACT Purposes: Shoulder arthroplasty (SA) has been performed by many years for the treatment of several conditions, including osteoarthritis and proximal humeral fractures following trauma. Surgical site infection (SSI) following Shoulder arthroplasty remains a challenge, contributing to increased morbidity and costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aimed to identify pre- and intra-operative risk factors associated with deep infections after Shoulder arthroplasty. Methods: An unmatched case-control study was conducted to describe the prevalence, clinical and microbiological findings, and to evaluate patient and surgical risk factors for prosthetic shoulder infection (PSI), among 158 patients who underwent SA due to any reason, at a tertiary public university institution. Risk factors for PSI was assessed by uni- and multivariate analyses using multiple logistic regression. Results: 168 SA from 158 patients were analyzed, with an overall infection rate of 9.5% (16/168 cases). Subjects undergoing SA with American Society of Anesthesiologists (ASA) grade III or higher (odds ratio [OR] = 5.30, 95% confidence interval [CI] = 1.58-17.79, p < 0.013) and presenting local hematoma after surgery (odds ratio [OR] = 7.10, 95% confidence interval [CI] = 1.09-46.09, p = 0.04) had higher risk for PSI on univariate analysis. However, only ASA score grade III or higher remained significant on multivariate analysis (OR = 4.74, 95% CI = 1.33-16.92, p = 0.016). Gram-positive cocci and Gram-negative bacilli were equally isolated in 50% of cases; however, the most commonly detected bacterium was Pseudomonas aeruginosa (18.7%). Conclusion: This study provides evidence suggesting that patient-related known factors such as higher ASA score predisposes to shoulder arthroplasty-associated infection. Furthermore, unusual pathogens associated with PSI were identified.
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spelling Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in BrazilOrthopedic infectionHemiarthroplastyTotal shoulder arthroplastyAmerican Society of Anesthesiologists scoreRisk factorPseudomonas aeruginosaABSTRACT Purposes: Shoulder arthroplasty (SA) has been performed by many years for the treatment of several conditions, including osteoarthritis and proximal humeral fractures following trauma. Surgical site infection (SSI) following Shoulder arthroplasty remains a challenge, contributing to increased morbidity and costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aimed to identify pre- and intra-operative risk factors associated with deep infections after Shoulder arthroplasty. Methods: An unmatched case-control study was conducted to describe the prevalence, clinical and microbiological findings, and to evaluate patient and surgical risk factors for prosthetic shoulder infection (PSI), among 158 patients who underwent SA due to any reason, at a tertiary public university institution. Risk factors for PSI was assessed by uni- and multivariate analyses using multiple logistic regression. Results: 168 SA from 158 patients were analyzed, with an overall infection rate of 9.5% (16/168 cases). Subjects undergoing SA with American Society of Anesthesiologists (ASA) grade III or higher (odds ratio [OR] = 5.30, 95% confidence interval [CI] = 1.58-17.79, p < 0.013) and presenting local hematoma after surgery (odds ratio [OR] = 7.10, 95% confidence interval [CI] = 1.09-46.09, p = 0.04) had higher risk for PSI on univariate analysis. However, only ASA score grade III or higher remained significant on multivariate analysis (OR = 4.74, 95% CI = 1.33-16.92, p = 0.016). Gram-positive cocci and Gram-negative bacilli were equally isolated in 50% of cases; however, the most commonly detected bacterium was Pseudomonas aeruginosa (18.7%). Conclusion: This study provides evidence suggesting that patient-related known factors such as higher ASA score predisposes to shoulder arthroplasty-associated infection. Furthermore, unusual pathogens associated with PSI were identified.Brazilian Society of Infectious Diseases2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600613Brazilian Journal of Infectious Diseases v.21 n.6 2017reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1016/j.bjid.2017.06.003info:eu-repo/semantics/openAccessNagaya,Leonardo HidetoSalles,Mauro José CostaTakikawa,Lucas Sadawo ChagasFregoneze,MarceloDoneux,PedroSilva,Luciana Andrade daSella,Guilherme do ValMiyazaki,Alberto NaokiChecchia,Sergio Luizeng2017-12-11T00:00:00Zoai:scielo:S1413-86702017000600613Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2017-12-11T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
title Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
spellingShingle Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
Nagaya,Leonardo Hideto
Orthopedic infection
Hemiarthroplasty
Total shoulder arthroplasty
American Society of Anesthesiologists score
Risk factor
Pseudomonas aeruginosa
title_short Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
title_full Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
title_fullStr Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
title_full_unstemmed Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
title_sort Infections after shoulder arthroplasty are correlated with higher anesthetic risk score: a case-control study in Brazil
author Nagaya,Leonardo Hideto
author_facet Nagaya,Leonardo Hideto
Salles,Mauro José Costa
Takikawa,Lucas Sadawo Chagas
Fregoneze,Marcelo
Doneux,Pedro
Silva,Luciana Andrade da
Sella,Guilherme do Val
Miyazaki,Alberto Naoki
Checchia,Sergio Luiz
author_role author
author2 Salles,Mauro José Costa
Takikawa,Lucas Sadawo Chagas
Fregoneze,Marcelo
Doneux,Pedro
Silva,Luciana Andrade da
Sella,Guilherme do Val
Miyazaki,Alberto Naoki
Checchia,Sergio Luiz
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nagaya,Leonardo Hideto
Salles,Mauro José Costa
Takikawa,Lucas Sadawo Chagas
Fregoneze,Marcelo
Doneux,Pedro
Silva,Luciana Andrade da
Sella,Guilherme do Val
Miyazaki,Alberto Naoki
Checchia,Sergio Luiz
dc.subject.por.fl_str_mv Orthopedic infection
Hemiarthroplasty
Total shoulder arthroplasty
American Society of Anesthesiologists score
Risk factor
Pseudomonas aeruginosa
topic Orthopedic infection
Hemiarthroplasty
Total shoulder arthroplasty
American Society of Anesthesiologists score
Risk factor
Pseudomonas aeruginosa
description ABSTRACT Purposes: Shoulder arthroplasty (SA) has been performed by many years for the treatment of several conditions, including osteoarthritis and proximal humeral fractures following trauma. Surgical site infection (SSI) following Shoulder arthroplasty remains a challenge, contributing to increased morbidity and costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aimed to identify pre- and intra-operative risk factors associated with deep infections after Shoulder arthroplasty. Methods: An unmatched case-control study was conducted to describe the prevalence, clinical and microbiological findings, and to evaluate patient and surgical risk factors for prosthetic shoulder infection (PSI), among 158 patients who underwent SA due to any reason, at a tertiary public university institution. Risk factors for PSI was assessed by uni- and multivariate analyses using multiple logistic regression. Results: 168 SA from 158 patients were analyzed, with an overall infection rate of 9.5% (16/168 cases). Subjects undergoing SA with American Society of Anesthesiologists (ASA) grade III or higher (odds ratio [OR] = 5.30, 95% confidence interval [CI] = 1.58-17.79, p < 0.013) and presenting local hematoma after surgery (odds ratio [OR] = 7.10, 95% confidence interval [CI] = 1.09-46.09, p = 0.04) had higher risk for PSI on univariate analysis. However, only ASA score grade III or higher remained significant on multivariate analysis (OR = 4.74, 95% CI = 1.33-16.92, p = 0.016). Gram-positive cocci and Gram-negative bacilli were equally isolated in 50% of cases; however, the most commonly detected bacterium was Pseudomonas aeruginosa (18.7%). Conclusion: This study provides evidence suggesting that patient-related known factors such as higher ASA score predisposes to shoulder arthroplasty-associated infection. Furthermore, unusual pathogens associated with PSI were identified.
publishDate 2017
dc.date.none.fl_str_mv 2017-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600613
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600613
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjid.2017.06.003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.21 n.6 2017
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
instname_str Brazilian Society of Infectious Diseases (BSID)
instacron_str BSID
institution BSID
reponame_str Brazilian Journal of Infectious Diseases
collection Brazilian Journal of Infectious Diseases
repository.name.fl_str_mv Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)
repository.mail.fl_str_mv bjid@bjid.org.br||lgoldani@ufrgs.br
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