Clinical signs, diagnosis, and case reports of Vaccinia virus infections
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003 |
Resumo: | Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold. Then, pustules and ulcerated lesions surrounded by edema and erythema follow, as well as local lymphadenopathy that can last for weeks. Cure and healing of the lesions occur over several weeks, leaving a typical scar in the skin of people and animals affected. The infection definitive diagnosis is made through morphological characterization of the virus by use of electron microscopy, followed by PCR for specific viral genes. Since 1963, circulating orthopoxviruses in infectious outbreaks in several regions of Brazil have been reported. Later, the etiological agent of those infections was characterized as samples of Vaccinia virus. In addition, the widespread use of those viruses in research laboratories and mass vaccination of militaries have contributed to increase the cases of those infections worldwide. Thus, several epidemiological and clinical studies are required, as well as studies of viral immunology, public health, and economic impact, because little is known about those Vaccinia virus outbreaks in Brazil. |
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Clinical signs, diagnosis, and case reports of Vaccinia virus infectionsPoxviridae infectionsvirologyoutbreakszoonosesVaccinia virusVaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold. Then, pustules and ulcerated lesions surrounded by edema and erythema follow, as well as local lymphadenopathy that can last for weeks. Cure and healing of the lesions occur over several weeks, leaving a typical scar in the skin of people and animals affected. The infection definitive diagnosis is made through morphological characterization of the virus by use of electron microscopy, followed by PCR for specific viral genes. Since 1963, circulating orthopoxviruses in infectious outbreaks in several regions of Brazil have been reported. Later, the etiological agent of those infections was characterized as samples of Vaccinia virus. In addition, the widespread use of those viruses in research laboratories and mass vaccination of militaries have contributed to increase the cases of those infections worldwide. Thus, several epidemiological and clinical studies are required, as well as studies of viral immunology, public health, and economic impact, because little is known about those Vaccinia virus outbreaks in Brazil.Brazilian Society of Infectious Diseases2010-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003Brazilian Journal of Infectious Diseases v.14 n.2 2010reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702010000200003info:eu-repo/semantics/openAccessSilva,Daniela Carla MedeirosMoreira-Silva,Eduardo Augusto dos SantosGomes,Juliana de Assis SilvaFonseca,Flávio Guimarães daCorrea-Oliveira,Rodrigoeng2010-06-18T00:00:00Zoai:scielo:S1413-86702010000200003Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2010-06-18T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
title |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
spellingShingle |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections Silva,Daniela Carla Medeiros Poxviridae infections virology outbreaks zoonoses Vaccinia virus |
title_short |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
title_full |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
title_fullStr |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
title_full_unstemmed |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
title_sort |
Clinical signs, diagnosis, and case reports of Vaccinia virus infections |
author |
Silva,Daniela Carla Medeiros |
author_facet |
Silva,Daniela Carla Medeiros Moreira-Silva,Eduardo Augusto dos Santos Gomes,Juliana de Assis Silva Fonseca,Flávio Guimarães da Correa-Oliveira,Rodrigo |
author_role |
author |
author2 |
Moreira-Silva,Eduardo Augusto dos Santos Gomes,Juliana de Assis Silva Fonseca,Flávio Guimarães da Correa-Oliveira,Rodrigo |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Silva,Daniela Carla Medeiros Moreira-Silva,Eduardo Augusto dos Santos Gomes,Juliana de Assis Silva Fonseca,Flávio Guimarães da Correa-Oliveira,Rodrigo |
dc.subject.por.fl_str_mv |
Poxviridae infections virology outbreaks zoonoses Vaccinia virus |
topic |
Poxviridae infections virology outbreaks zoonoses Vaccinia virus |
description |
Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold. Then, pustules and ulcerated lesions surrounded by edema and erythema follow, as well as local lymphadenopathy that can last for weeks. Cure and healing of the lesions occur over several weeks, leaving a typical scar in the skin of people and animals affected. The infection definitive diagnosis is made through morphological characterization of the virus by use of electron microscopy, followed by PCR for specific viral genes. Since 1963, circulating orthopoxviruses in infectious outbreaks in several regions of Brazil have been reported. Later, the etiological agent of those infections was characterized as samples of Vaccinia virus. In addition, the widespread use of those viruses in research laboratories and mass vaccination of militaries have contributed to increase the cases of those infections worldwide. Thus, several epidemiological and clinical studies are required, as well as studies of viral immunology, public health, and economic impact, because little is known about those Vaccinia virus outbreaks in Brazil. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1413-86702010000200003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.14 n.2 2010 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
_version_ |
1754209241137152000 |