Clinical signs, diagnosis, and case reports of Vaccinia virus infections

Detalhes bibliográficos
Autor(a) principal: Silva,Daniela Carla Medeiros
Data de Publicação: 2010
Outros Autores: Moreira-Silva,Eduardo Augusto dos Santos, Gomes,Juliana de Assis Silva, Fonseca,Flávio Guimarães da, Correa-Oliveira,Rodrigo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Infectious Diseases
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003
Resumo: Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold. Then, pustules and ulcerated lesions surrounded by edema and erythema follow, as well as local lymphadenopathy that can last for weeks. Cure and healing of the lesions occur over several weeks, leaving a typical scar in the skin of people and animals affected. The infection definitive diagnosis is made through morphological characterization of the virus by use of electron microscopy, followed by PCR for specific viral genes. Since 1963, circulating orthopoxviruses in infectious outbreaks in several regions of Brazil have been reported. Later, the etiological agent of those infections was characterized as samples of Vaccinia virus. In addition, the widespread use of those viruses in research laboratories and mass vaccination of militaries have contributed to increase the cases of those infections worldwide. Thus, several epidemiological and clinical studies are required, as well as studies of viral immunology, public health, and economic impact, because little is known about those Vaccinia virus outbreaks in Brazil.
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spelling Clinical signs, diagnosis, and case reports of Vaccinia virus infectionsPoxviridae infectionsvirologyoutbreakszoonosesVaccinia virusVaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold. Then, pustules and ulcerated lesions surrounded by edema and erythema follow, as well as local lymphadenopathy that can last for weeks. Cure and healing of the lesions occur over several weeks, leaving a typical scar in the skin of people and animals affected. The infection definitive diagnosis is made through morphological characterization of the virus by use of electron microscopy, followed by PCR for specific viral genes. Since 1963, circulating orthopoxviruses in infectious outbreaks in several regions of Brazil have been reported. Later, the etiological agent of those infections was characterized as samples of Vaccinia virus. In addition, the widespread use of those viruses in research laboratories and mass vaccination of militaries have contributed to increase the cases of those infections worldwide. Thus, several epidemiological and clinical studies are required, as well as studies of viral immunology, public health, and economic impact, because little is known about those Vaccinia virus outbreaks in Brazil.Brazilian Society of Infectious Diseases2010-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003Brazilian Journal of Infectious Diseases v.14 n.2 2010reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1590/S1413-86702010000200003info:eu-repo/semantics/openAccessSilva,Daniela Carla MedeirosMoreira-Silva,Eduardo Augusto dos SantosGomes,Juliana de Assis SilvaFonseca,Flávio Guimarães daCorrea-Oliveira,Rodrigoeng2010-06-18T00:00:00Zoai:scielo:S1413-86702010000200003Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2010-06-18T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false
dc.title.none.fl_str_mv Clinical signs, diagnosis, and case reports of Vaccinia virus infections
title Clinical signs, diagnosis, and case reports of Vaccinia virus infections
spellingShingle Clinical signs, diagnosis, and case reports of Vaccinia virus infections
Silva,Daniela Carla Medeiros
Poxviridae infections
virology
outbreaks
zoonoses
Vaccinia virus
title_short Clinical signs, diagnosis, and case reports of Vaccinia virus infections
title_full Clinical signs, diagnosis, and case reports of Vaccinia virus infections
title_fullStr Clinical signs, diagnosis, and case reports of Vaccinia virus infections
title_full_unstemmed Clinical signs, diagnosis, and case reports of Vaccinia virus infections
title_sort Clinical signs, diagnosis, and case reports of Vaccinia virus infections
author Silva,Daniela Carla Medeiros
author_facet Silva,Daniela Carla Medeiros
Moreira-Silva,Eduardo Augusto dos Santos
Gomes,Juliana de Assis Silva
Fonseca,Flávio Guimarães da
Correa-Oliveira,Rodrigo
author_role author
author2 Moreira-Silva,Eduardo Augusto dos Santos
Gomes,Juliana de Assis Silva
Fonseca,Flávio Guimarães da
Correa-Oliveira,Rodrigo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva,Daniela Carla Medeiros
Moreira-Silva,Eduardo Augusto dos Santos
Gomes,Juliana de Assis Silva
Fonseca,Flávio Guimarães da
Correa-Oliveira,Rodrigo
dc.subject.por.fl_str_mv Poxviridae infections
virology
outbreaks
zoonoses
Vaccinia virus
topic Poxviridae infections
virology
outbreaks
zoonoses
Vaccinia virus
description Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold. Then, pustules and ulcerated lesions surrounded by edema and erythema follow, as well as local lymphadenopathy that can last for weeks. Cure and healing of the lesions occur over several weeks, leaving a typical scar in the skin of people and animals affected. The infection definitive diagnosis is made through morphological characterization of the virus by use of electron microscopy, followed by PCR for specific viral genes. Since 1963, circulating orthopoxviruses in infectious outbreaks in several regions of Brazil have been reported. Later, the etiological agent of those infections was characterized as samples of Vaccinia virus. In addition, the widespread use of those viruses in research laboratories and mass vaccination of militaries have contributed to increase the cases of those infections worldwide. Thus, several epidemiological and clinical studies are required, as well as studies of viral immunology, public health, and economic impact, because little is known about those Vaccinia virus outbreaks in Brazil.
publishDate 2010
dc.date.none.fl_str_mv 2010-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1413-86702010000200003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
publisher.none.fl_str_mv Brazilian Society of Infectious Diseases
dc.source.none.fl_str_mv Brazilian Journal of Infectious Diseases v.14 n.2 2010
reponame:Brazilian Journal of Infectious Diseases
instname:Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
instname_str Brazilian Society of Infectious Diseases (BSID)
instacron_str BSID
institution BSID
reponame_str Brazilian Journal of Infectious Diseases
collection Brazilian Journal of Infectious Diseases
repository.name.fl_str_mv Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)
repository.mail.fl_str_mv bjid@bjid.org.br||lgoldani@ufrgs.br
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