Should splenic autotransplantation be considered after total splenectomy due to trauma?

Detalhes bibliográficos
Autor(a) principal: CARDOSO,DANIEL LINHARES
Data de Publicação: 2018
Outros Autores: CARDOSO FILHO,FLORENTINO DE ARAÚJO, CARDOSO,AMANDA LINHARES, GONZAGA,MARCELO LIMA, GRANDE,ANTÔNIO JOSÉ
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Colégio Brasileiro de Cirurgiões
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912018000300300
Resumo: ABSTRACT Trauma is a public health problem and the most common cause of death in people under the age of 45. In blunt abdominal trauma, the spleen is the most commonly injured organ. Splenectomy remains the most common treatment, especially in high-grade lesions, despite increased nonoperative treatment. Removal of the spleen leads to increased susceptibility to infections due to its role in the immune function. Postsplenectomy sepsis is an important complication and presents a high mortality rate. Patients undergoing splenectomy should be immunized for encapsulated germs, as these are the agents most commonly associated with such infections. Splenic autotransplantation is a simple procedure, which can be an alternative to reduce infection rates consequent to total splenectomy, and reduce costs related to hospitalizations. This review aims to provide evidence-based information on splenic autotransplantation and its impact on the prognosis of patients undergoing total splenectomy. We searched the Cochrane Library, Medline/PubMed, SciELO and Embase, from January 2017 to January 2018 and selected articles in English and Portuguese, dated from 1919 to 2017. We found that the adjusted risk of death in splenectomized patients is greater than that of the general population, and when total splenectomy is performed, splenic autotransplantation is the only method capable of preserving splenic function, avoiding infections, especially postsplenectomy sepsis. Health professionals should be familiar with the consequences of the method chosen to manage the patient suffering from splenic trauma.
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spelling Should splenic autotransplantation be considered after total splenectomy due to trauma?Trauma and Stressor Related DisordersSpleenSplenectomySepsisTransplantation, Autologous.ABSTRACT Trauma is a public health problem and the most common cause of death in people under the age of 45. In blunt abdominal trauma, the spleen is the most commonly injured organ. Splenectomy remains the most common treatment, especially in high-grade lesions, despite increased nonoperative treatment. Removal of the spleen leads to increased susceptibility to infections due to its role in the immune function. Postsplenectomy sepsis is an important complication and presents a high mortality rate. Patients undergoing splenectomy should be immunized for encapsulated germs, as these are the agents most commonly associated with such infections. Splenic autotransplantation is a simple procedure, which can be an alternative to reduce infection rates consequent to total splenectomy, and reduce costs related to hospitalizations. This review aims to provide evidence-based information on splenic autotransplantation and its impact on the prognosis of patients undergoing total splenectomy. We searched the Cochrane Library, Medline/PubMed, SciELO and Embase, from January 2017 to January 2018 and selected articles in English and Portuguese, dated from 1919 to 2017. We found that the adjusted risk of death in splenectomized patients is greater than that of the general population, and when total splenectomy is performed, splenic autotransplantation is the only method capable of preserving splenic function, avoiding infections, especially postsplenectomy sepsis. Health professionals should be familiar with the consequences of the method chosen to manage the patient suffering from splenic trauma.Colégio Brasileiro de Cirurgiões2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912018000300300Revista do Colégio Brasileiro de Cirurgiões v.45 n.3 2018reponame:Revista do Colégio Brasileiro de Cirurgiõesinstname:Colégio Brasileiro de Cirurgiões (CBC)instacron:CBC10.1590/0100-6991e-20181850info:eu-repo/semantics/openAccessCARDOSO,DANIEL LINHARESCARDOSO FILHO,FLORENTINO DE ARAÚJOCARDOSO,AMANDA LINHARESGONZAGA,MARCELO LIMAGRANDE,ANTÔNIO JOSÉeng2018-07-04T00:00:00Zoai:scielo:S0100-69912018000300300Revistahttp://www.scielo.br/rcbcONGhttps://old.scielo.br/oai/scielo-oai.php||revistacbc@cbc.org.br1809-45460100-6991opendoar:2018-07-04T00:00Revista do Colégio Brasileiro de Cirurgiões - Colégio Brasileiro de Cirurgiões (CBC)false
dc.title.none.fl_str_mv Should splenic autotransplantation be considered after total splenectomy due to trauma?
title Should splenic autotransplantation be considered after total splenectomy due to trauma?
spellingShingle Should splenic autotransplantation be considered after total splenectomy due to trauma?
CARDOSO,DANIEL LINHARES
Trauma and Stressor Related Disorders
Spleen
Splenectomy
Sepsis
Transplantation, Autologous.
title_short Should splenic autotransplantation be considered after total splenectomy due to trauma?
title_full Should splenic autotransplantation be considered after total splenectomy due to trauma?
title_fullStr Should splenic autotransplantation be considered after total splenectomy due to trauma?
title_full_unstemmed Should splenic autotransplantation be considered after total splenectomy due to trauma?
title_sort Should splenic autotransplantation be considered after total splenectomy due to trauma?
author CARDOSO,DANIEL LINHARES
author_facet CARDOSO,DANIEL LINHARES
CARDOSO FILHO,FLORENTINO DE ARAÚJO
CARDOSO,AMANDA LINHARES
GONZAGA,MARCELO LIMA
GRANDE,ANTÔNIO JOSÉ
author_role author
author2 CARDOSO FILHO,FLORENTINO DE ARAÚJO
CARDOSO,AMANDA LINHARES
GONZAGA,MARCELO LIMA
GRANDE,ANTÔNIO JOSÉ
author2_role author
author
author
author
dc.contributor.author.fl_str_mv CARDOSO,DANIEL LINHARES
CARDOSO FILHO,FLORENTINO DE ARAÚJO
CARDOSO,AMANDA LINHARES
GONZAGA,MARCELO LIMA
GRANDE,ANTÔNIO JOSÉ
dc.subject.por.fl_str_mv Trauma and Stressor Related Disorders
Spleen
Splenectomy
Sepsis
Transplantation, Autologous.
topic Trauma and Stressor Related Disorders
Spleen
Splenectomy
Sepsis
Transplantation, Autologous.
description ABSTRACT Trauma is a public health problem and the most common cause of death in people under the age of 45. In blunt abdominal trauma, the spleen is the most commonly injured organ. Splenectomy remains the most common treatment, especially in high-grade lesions, despite increased nonoperative treatment. Removal of the spleen leads to increased susceptibility to infections due to its role in the immune function. Postsplenectomy sepsis is an important complication and presents a high mortality rate. Patients undergoing splenectomy should be immunized for encapsulated germs, as these are the agents most commonly associated with such infections. Splenic autotransplantation is a simple procedure, which can be an alternative to reduce infection rates consequent to total splenectomy, and reduce costs related to hospitalizations. This review aims to provide evidence-based information on splenic autotransplantation and its impact on the prognosis of patients undergoing total splenectomy. We searched the Cochrane Library, Medline/PubMed, SciELO and Embase, from January 2017 to January 2018 and selected articles in English and Portuguese, dated from 1919 to 2017. We found that the adjusted risk of death in splenectomized patients is greater than that of the general population, and when total splenectomy is performed, splenic autotransplantation is the only method capable of preserving splenic function, avoiding infections, especially postsplenectomy sepsis. Health professionals should be familiar with the consequences of the method chosen to manage the patient suffering from splenic trauma.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912018000300300
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0100-6991e-20181850
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Colégio Brasileiro de Cirurgiões
publisher.none.fl_str_mv Colégio Brasileiro de Cirurgiões
dc.source.none.fl_str_mv Revista do Colégio Brasileiro de Cirurgiões v.45 n.3 2018
reponame:Revista do Colégio Brasileiro de Cirurgiões
instname:Colégio Brasileiro de Cirurgiões (CBC)
instacron:CBC
instname_str Colégio Brasileiro de Cirurgiões (CBC)
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reponame_str Revista do Colégio Brasileiro de Cirurgiões
collection Revista do Colégio Brasileiro de Cirurgiões
repository.name.fl_str_mv Revista do Colégio Brasileiro de Cirurgiões - Colégio Brasileiro de Cirurgiões (CBC)
repository.mail.fl_str_mv ||revistacbc@cbc.org.br
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