Comparative analysis of endoscopic and histopathological features of superficial elevated lesions resected by endoscopic mucosal resection in the distal and proximal colon

• Autor(a) principal: PARADA,ARTUR ADOLFO
• Data de Publicação: 2016
• Outros Autores: RIBAS,CARMEN AUSTRALIA PAREDE MARCONDES, VENCO,FILADELFIO EUCLYDES, ARDENGH,JOSÉ CELSO, REIS,MARIANA AMARAL, DEGIOVANI,MATHEUS, VARCA-NETO,MIGUEL REYNALDO, DIGER,NILDEDE RODRIGUES, IBRAHIM,ROBERTO EL, CORDOVA,KASSIA FERNANDA, FAGUNDES,MARÍLIA DA CRUZ, MOREIRA,HAMILTON, KUBRUSLY,LUIZ FERNANDO
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Colégio Brasileiro de Cirurgiões
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912016000300178
• topic: Colorectal Neoplasms; Endoscopy; Mucous Membrane; Colon; Colonoscopy.

ABSTRACT Objective: to compare endoscopic and histopathologic features of superficial, elevated lesions with one or more centimeters in diameter, diagnosed by videocolonoscopy on the distal and proximal colon, and subjected to mucosal resection. Methods: we conducted a retrospective, cross-sectional, observational study involving 8,075 videocolonoscopies. From this total, we evaluated 166 mucosectomies in 145 patients with superficial, elevated lesions with a diameter equal to or greater than 1cm. Results: the lesion prevalence was lower in G1 than in G2 (34.9% vs. 65%). The mean age, gender distribution and size (1.9cm in G1 versus 2.0cm in G2, p=0.921) were similar. There was no difference of mucosal surfaces in relation to the location (p=0.575). Considering Intraepithelial neoplasias, both the low grade, high grade (including carcinomas) and hyperplasic ones showedd no difference (p=0.527), nor did the neoplastic lesions when divided into serrated and non-serrated (p=0.124). Excluding 13 hyperplastic lesions and two carcinomas, 124 (82.1%) were non-serrated and 27 (17.9%), serrated. Conclusion: were found no significant differences between endoscopic and histopathological aspects of superficial, elevated lesions of 1cm or more in diameter in distal colon compared with the proximal, when resected by mucosectomy. Although not significant, there was a tendency of association between the location of the lesion and the presence of serrated features.