Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Colégio Brasileiro de Cirurgiões |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912021000100202 |
Resumo: | ABSTRACT Introduction: twin-to-twin transfusion syndrome (TTTS), defined by combination of polyhydramnios-oligohydramnios, is the most prevalent (5%-35%) of the abnormalities due to placental vascular anastomoses and the most lethal (80%-100% mortality) if untreated. Fetoscopic laser ablation of abnormal vasculature using the Solomon technique is the gold standard approach. It consists of interrupting the intertwin blood flow. Objectives: to present our initial experience at the Fetal Surgery Service of the Hospital de Clinicas of the Federal University of Parana (HC-UFPR) and to compare our results with those reported in the literature. Methods: we conducted a retrospective analysis of pregnancies who had undergone laser ablation, assessing data on Quintero’s staging, gestational age at diagnosis and at the time of the procedure, placental position, immediate post-procedure survival, and survival after the neonatal period. We then compared these data with the most recent data available in the literature. Results: we analyzed ten TTTS cases. The diagnosis was performed before the 26th week of pregnancy (median 20.8 weeks) and treatment occurred in a median of 9.5 days later. The distribution by the Quintero’s staging was of three cases in stage II, five in stage III, and two in stage IV. In 50% of the gestations, at least one of the fetuses survived through the neonatal period. Conclusion: the treatment of TTTS in the HC-UFPR had a positive impact in the survival of the affected fetuses, although the results were worse than the ones reported in the literature, probably due to the delay in referencing the patients to our service, leading to a prolonged interval between diagnosis and treatment. |
id |
CBC-1_815a37e807f1b733bd607d209612038e |
---|---|
oai_identifier_str |
oai:scielo:S0100-69912021000100202 |
network_acronym_str |
CBC-1 |
network_name_str |
Revista do Colégio Brasileiro de Cirurgiões |
repository_id_str |
|
spelling |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatmentFetofetal TransfusionLaser CoagulationTwinsABSTRACT Introduction: twin-to-twin transfusion syndrome (TTTS), defined by combination of polyhydramnios-oligohydramnios, is the most prevalent (5%-35%) of the abnormalities due to placental vascular anastomoses and the most lethal (80%-100% mortality) if untreated. Fetoscopic laser ablation of abnormal vasculature using the Solomon technique is the gold standard approach. It consists of interrupting the intertwin blood flow. Objectives: to present our initial experience at the Fetal Surgery Service of the Hospital de Clinicas of the Federal University of Parana (HC-UFPR) and to compare our results with those reported in the literature. Methods: we conducted a retrospective analysis of pregnancies who had undergone laser ablation, assessing data on Quintero’s staging, gestational age at diagnosis and at the time of the procedure, placental position, immediate post-procedure survival, and survival after the neonatal period. We then compared these data with the most recent data available in the literature. Results: we analyzed ten TTTS cases. The diagnosis was performed before the 26th week of pregnancy (median 20.8 weeks) and treatment occurred in a median of 9.5 days later. The distribution by the Quintero’s staging was of three cases in stage II, five in stage III, and two in stage IV. In 50% of the gestations, at least one of the fetuses survived through the neonatal period. Conclusion: the treatment of TTTS in the HC-UFPR had a positive impact in the survival of the affected fetuses, although the results were worse than the ones reported in the literature, probably due to the delay in referencing the patients to our service, leading to a prolonged interval between diagnosis and treatment.Colégio Brasileiro de Cirurgiões2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912021000100202Revista do Colégio Brasileiro de Cirurgiões v.48 2021reponame:Revista do Colégio Brasileiro de Cirurgiõesinstname:Colégio Brasileiro de Cirurgiões (CBC)instacron:CBC10.1590/0100-6991e-20202671info:eu-repo/semantics/openAccessREZENDE,THAMYLE MODA DE SANTANAWEIHERMANN,VIKTORIAFACHIN,CAMILA GIRARDIBRUNS,RAFAEL FREDERICODIAS,ANDRÉ IVAN BRADLEY SANTOSeng2021-01-15T00:00:00Zoai:scielo:S0100-69912021000100202Revistahttp://www.scielo.br/rcbcONGhttps://old.scielo.br/oai/scielo-oai.php||revistacbc@cbc.org.br1809-45460100-6991opendoar:2021-01-15T00:00Revista do Colégio Brasileiro de Cirurgiões - Colégio Brasileiro de Cirurgiões (CBC)false |
dc.title.none.fl_str_mv |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
title |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
spellingShingle |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment REZENDE,THAMYLE MODA DE SANTANA Fetofetal Transfusion Laser Coagulation Twins |
title_short |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
title_full |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
title_fullStr |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
title_full_unstemmed |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
title_sort |
Twin-twin transfusion syndrome - a University Hospital experience with intrauterine treatment |
author |
REZENDE,THAMYLE MODA DE SANTANA |
author_facet |
REZENDE,THAMYLE MODA DE SANTANA WEIHERMANN,VIKTORIA FACHIN,CAMILA GIRARDI BRUNS,RAFAEL FREDERICO DIAS,ANDRÉ IVAN BRADLEY SANTOS |
author_role |
author |
author2 |
WEIHERMANN,VIKTORIA FACHIN,CAMILA GIRARDI BRUNS,RAFAEL FREDERICO DIAS,ANDRÉ IVAN BRADLEY SANTOS |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
REZENDE,THAMYLE MODA DE SANTANA WEIHERMANN,VIKTORIA FACHIN,CAMILA GIRARDI BRUNS,RAFAEL FREDERICO DIAS,ANDRÉ IVAN BRADLEY SANTOS |
dc.subject.por.fl_str_mv |
Fetofetal Transfusion Laser Coagulation Twins |
topic |
Fetofetal Transfusion Laser Coagulation Twins |
description |
ABSTRACT Introduction: twin-to-twin transfusion syndrome (TTTS), defined by combination of polyhydramnios-oligohydramnios, is the most prevalent (5%-35%) of the abnormalities due to placental vascular anastomoses and the most lethal (80%-100% mortality) if untreated. Fetoscopic laser ablation of abnormal vasculature using the Solomon technique is the gold standard approach. It consists of interrupting the intertwin blood flow. Objectives: to present our initial experience at the Fetal Surgery Service of the Hospital de Clinicas of the Federal University of Parana (HC-UFPR) and to compare our results with those reported in the literature. Methods: we conducted a retrospective analysis of pregnancies who had undergone laser ablation, assessing data on Quintero’s staging, gestational age at diagnosis and at the time of the procedure, placental position, immediate post-procedure survival, and survival after the neonatal period. We then compared these data with the most recent data available in the literature. Results: we analyzed ten TTTS cases. The diagnosis was performed before the 26th week of pregnancy (median 20.8 weeks) and treatment occurred in a median of 9.5 days later. The distribution by the Quintero’s staging was of three cases in stage II, five in stage III, and two in stage IV. In 50% of the gestations, at least one of the fetuses survived through the neonatal period. Conclusion: the treatment of TTTS in the HC-UFPR had a positive impact in the survival of the affected fetuses, although the results were worse than the ones reported in the literature, probably due to the delay in referencing the patients to our service, leading to a prolonged interval between diagnosis and treatment. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912021000100202 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912021000100202 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0100-6991e-20202671 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Colégio Brasileiro de Cirurgiões |
publisher.none.fl_str_mv |
Colégio Brasileiro de Cirurgiões |
dc.source.none.fl_str_mv |
Revista do Colégio Brasileiro de Cirurgiões v.48 2021 reponame:Revista do Colégio Brasileiro de Cirurgiões instname:Colégio Brasileiro de Cirurgiões (CBC) instacron:CBC |
instname_str |
Colégio Brasileiro de Cirurgiões (CBC) |
instacron_str |
CBC |
institution |
CBC |
reponame_str |
Revista do Colégio Brasileiro de Cirurgiões |
collection |
Revista do Colégio Brasileiro de Cirurgiões |
repository.name.fl_str_mv |
Revista do Colégio Brasileiro de Cirurgiões - Colégio Brasileiro de Cirurgiões (CBC) |
repository.mail.fl_str_mv |
||revistacbc@cbc.org.br |
_version_ |
1754209215053824000 |