PROTOCOL FOR LIVER TRANSPLANTATION IN HILAR CHOLANGIOCARCINOMA

• Autor(a) principal: ERNANI,Lucas
• Data de Publicação: 2021
• Outros Autores: MARTINO,Rodrigo Bronze de, ANDRAUS,Wellington, FERNANDES,Eduardo de Souza Martins, MELLO,Felipe Pedreira Tavares de, ANDRADE,Ronaldo, PIMENTEL,Leandro Savattone, HADDAD,Luciana Bertocco de Paiva, COELHO,Fabricio Ferreira, HERMAN,Paulo, D’ALBUQUERQUE,Luiz Augusto Carneiro
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-67202021000300403
• topic: Transplantation; Liver transplantation; Cholangiocarcinoma; Klatskin tumor

ABSTRACT Background: Hilar cholangiocarcinoma represents more than half of all cholangiocarcinoma cases, having poor prognosis and presenting a median overall survival after diagnosis of 12-24 months. In patients who have unresectable tumors with a better prognosis, the proposal to perform liver transplantation emerged for expanding the possibility of free margins by performing total hepatectomy. Aim: To provide a Brazilian protocol for liver transplantation in patients with hilar cholangiocarcinoma. Method: The protocol was carried out by two Brazilian institutions which perform a large volume of resections and liver transplantations, based on the study carried out at the Mayo Clinic. The elaboration of the protocol was conducted in four stages. Result: A protocol proposal for this disease is presented, which needs to be validated for clinical use. Conclusion: The development of a liver transplantation protocol for cholangiocarcinoma aims not only to standardize the treatment, but also enable a better assessment of the surgical results in the future.