Clinical and histopathological features of orbital granular cell tumor: case report

• Autor(a) principal: Fernandes,Bruno F.
• Data de Publicação: 2012
• Outros Autores: Belfort Neto,Rubens, Odashiro,Alexandre Nakao, Pereira,Patricia Rusa, Burnier Jr.,Miguel N.
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Arquivos brasileiros de oftalmologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492012000200014
• topic: Orbital neoplasms/diagnosis; Exophthalmos; Tomography, X-ray computed; Case report

A 53 year-old woman presented with a slowly progressive, painless proptosis OS. Computed tomography disclosed a round, homogeneous, well-delimited lesion in the inferior-temporal orbit. The tumor was composed of round cells with eosinophilic granular cytoplasm. Some of the cells had larger eosinophilic granules surrounded by a clear halo; known as pustulo-ovoid bodies of Milian or Bangle bodies. The diagnosis of a granular cell tumor was then established and confirmed by immunohistochemistry. Granular cell tumors are uncommon benign soft tissue neoplasms that have a predilection for the head and neck region. Awareness of the typical histopathological features is crucial for the correct diagnosis.