Eyelid aging: pathophysiology and clinical management

Detalhes bibliográficos
Autor(a) principal: Damasceno,Renato Wendell
Data de Publicação: 2015
Outros Autores: Avgitidou,Georgia, Belfort Jr.,Rubens, Dantas,Paulo Elias Correa, Holbach,Leonard M., Heindl,Ludwig M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000550087
Resumo: ABSTRACTLife expectancy is increasing in most countries. With increasing age, many individuals may develop involutional ophthalmic diseases, such as eyelid aging. Dermatochalasis, ptosis, ectropion, and entropion are common disorders in middle-aged and older adults. This review outlines the pathophysiology and clinical management of these involutional eyelid disorders. Recently, a decrease in elastic fibers with ultrastructural abnormalities and an overexpression of elastin-degrading enzymes have been demonstrated in involutional ectropion and entropion. This may be the consequence of local ischemia, inflammation, and/or chronic mechanical stress. Eyelid aging with progressive loss of tone and laxity may affect the ocular surface and adnexal tissues, resulting in different clinical symptoms and signs. Surgical management depends on the appropriate correction of the underlying anatomical defect.
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spelling Eyelid aging: pathophysiology and clinical managementAgingEyelidEyelid diseasesEctropionEntropionExtracellular matrixElastinMatrix metalloproteinasesABSTRACTLife expectancy is increasing in most countries. With increasing age, many individuals may develop involutional ophthalmic diseases, such as eyelid aging. Dermatochalasis, ptosis, ectropion, and entropion are common disorders in middle-aged and older adults. This review outlines the pathophysiology and clinical management of these involutional eyelid disorders. Recently, a decrease in elastic fibers with ultrastructural abnormalities and an overexpression of elastin-degrading enzymes have been demonstrated in involutional ectropion and entropion. This may be the consequence of local ischemia, inflammation, and/or chronic mechanical stress. Eyelid aging with progressive loss of tone and laxity may affect the ocular surface and adnexal tissues, resulting in different clinical symptoms and signs. Surgical management depends on the appropriate correction of the underlying anatomical defect.Conselho Brasileiro de Oftalmologia2015-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000550087Arquivos Brasileiros de Oftalmologia v.78 n.5 2015reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20150087info:eu-repo/semantics/openAccessDamasceno,Renato WendellAvgitidou,GeorgiaBelfort Jr.,RubensDantas,Paulo Elias CorreaHolbach,Leonard M.Heindl,Ludwig M.eng2015-10-02T00:00:00Zoai:scielo:S0004-27492015000550087Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2015-10-02T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Eyelid aging: pathophysiology and clinical management
title Eyelid aging: pathophysiology and clinical management
spellingShingle Eyelid aging: pathophysiology and clinical management
Damasceno,Renato Wendell
Aging
Eyelid
Eyelid diseases
Ectropion
Entropion
Extracellular matrix
Elastin
Matrix metalloproteinases
title_short Eyelid aging: pathophysiology and clinical management
title_full Eyelid aging: pathophysiology and clinical management
title_fullStr Eyelid aging: pathophysiology and clinical management
title_full_unstemmed Eyelid aging: pathophysiology and clinical management
title_sort Eyelid aging: pathophysiology and clinical management
author Damasceno,Renato Wendell
author_facet Damasceno,Renato Wendell
Avgitidou,Georgia
Belfort Jr.,Rubens
Dantas,Paulo Elias Correa
Holbach,Leonard M.
Heindl,Ludwig M.
author_role author
author2 Avgitidou,Georgia
Belfort Jr.,Rubens
Dantas,Paulo Elias Correa
Holbach,Leonard M.
Heindl,Ludwig M.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Damasceno,Renato Wendell
Avgitidou,Georgia
Belfort Jr.,Rubens
Dantas,Paulo Elias Correa
Holbach,Leonard M.
Heindl,Ludwig M.
dc.subject.por.fl_str_mv Aging
Eyelid
Eyelid diseases
Ectropion
Entropion
Extracellular matrix
Elastin
Matrix metalloproteinases
topic Aging
Eyelid
Eyelid diseases
Ectropion
Entropion
Extracellular matrix
Elastin
Matrix metalloproteinases
description ABSTRACTLife expectancy is increasing in most countries. With increasing age, many individuals may develop involutional ophthalmic diseases, such as eyelid aging. Dermatochalasis, ptosis, ectropion, and entropion are common disorders in middle-aged and older adults. This review outlines the pathophysiology and clinical management of these involutional eyelid disorders. Recently, a decrease in elastic fibers with ultrastructural abnormalities and an overexpression of elastin-degrading enzymes have been demonstrated in involutional ectropion and entropion. This may be the consequence of local ischemia, inflammation, and/or chronic mechanical stress. Eyelid aging with progressive loss of tone and laxity may affect the ocular surface and adnexal tissues, resulting in different clinical symptoms and signs. Surgical management depends on the appropriate correction of the underlying anatomical defect.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000550087
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000550087
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20150087
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.78 n.5 2015
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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