Choroidal changes in pre-eclampsia during pregnancy and the postpartum period: comparison with healthy pregnancy

• Autor(a) principal: Duru,Necati
• Data de Publicação: 2016
• Outros Autores: Ulusoy,Döndü Melek, Özköse,Ayşe, Ataş,Mustafa, Karatepe,Arzu Seyhan, Ataş,Fatma, Arifoğlu,Hasan Basri, Yılmaz,Uğur
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Arquivos brasileiros de oftalmologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000300143
• topic: Choroid; Choroid diseases/diagnosis; Tomography, Optical coherence; Pre-eclampsia; Fovea centralis; Axial length; eye; Pregnancy

ABSTRACT Purpose: To investigate subfoveal choroidal thickness (SFCT) in patients with pre-eclampsia using enhanced depth imaging optical coherence tomography (EDI-OCT). Methods: A sample of 73 pregnant women was studied over 28 weeks of gestation. The sample was divided into two groups: one comprising pre-eclamptic pregnant women (n=32), and the other comprising healthy pregnant women (n=41). The SFCT was determined for all patients using EDI-OCT during pregnancy and at the third month of the postpartum period. Results: The SFCTs in pre-eclamptic pregnant women were 351.97 ± 22.44 and 332.28 ± 20.32 µm during the pregnancy and postpartum periods (p<0.001), respectively, whereas these values in healthy pregnant women were 389.73 ± 49.64 and 329.78 ± 22.36 µm (p<0.001), respectively. During pregnancy SFCT in pre-eclamptic pregnant women was significantly thinner than that in healthy pregnant women (p<0.001). However, there was no statistically significant difference during the postpartum period (p=0.623). Conclusions: The results suggest that SFCT is significantly decreased in pre-eclamptic pregnant women than in healthy pregnant women, despite no statistically significant difference in SFCT existing between the groups during the postpartum period.