Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies

Detalhes bibliográficos
Autor(a) principal: Yuksel,Erdem
Data de Publicação: 2016
Outros Autores: Cubuk,Mehmet Ozgur, Eroglu,Hulya Yazıcı, Bilgihan,Kamil
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000200069
Resumo: ABSTRACT Purpose: To evaluate the visual outcomes, recurrence patterns, safety, and efficacy of excimer laser phototherapeutic keratectomy (PTK) in conjunction with mitomycin C (MMC) for corneal macular and granular diystrophies. Methods: The patients were divided into two groups. Group 1 included patients with macular corneal dystrophy (MCD) that caused superficial corneal plaque opacities, and Group 2 included patients with granular corneal dystrophy (GCD). Patients in both groups were pre-, peri-, and postoperatively evaluated. The groups were compared in terms of uncorrected visual acuity (VA), best spectacle-corrected VA, presence of mild or significant recurrence, and time of recurrence. Results: Eighteen eyes (nine with MCD and nine with GCD) of 18 patients (10 men and eight women) were included. PTK was performed for each eye that was included in this study. The mean ablation amount was 117.8 ± 24.4 µm and 83.5 ± 45.7 µm in MCD and GCD, respectively, (p=0.18). The postoperative improvement of the mean VA was similar between the two groups before recurrences (p>0.43) and after recurrences (p>0.71). There were no statistically significant differences in the recurrence rate and the recurrence-free period for any recurrence type. Conclusion: PTK was an effective, safe, and minimally invasive procedure for patients with MCD and GCD. PTK in conjunction with MMC was similarly effective for both groups in terms of recurrence and visual outcomes.
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spelling Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophiesPhotorefractive keratectomyCorneal dystrophiesCornea physiopathologyMitomycinVisual acuityABSTRACT Purpose: To evaluate the visual outcomes, recurrence patterns, safety, and efficacy of excimer laser phototherapeutic keratectomy (PTK) in conjunction with mitomycin C (MMC) for corneal macular and granular diystrophies. Methods: The patients were divided into two groups. Group 1 included patients with macular corneal dystrophy (MCD) that caused superficial corneal plaque opacities, and Group 2 included patients with granular corneal dystrophy (GCD). Patients in both groups were pre-, peri-, and postoperatively evaluated. The groups were compared in terms of uncorrected visual acuity (VA), best spectacle-corrected VA, presence of mild or significant recurrence, and time of recurrence. Results: Eighteen eyes (nine with MCD and nine with GCD) of 18 patients (10 men and eight women) were included. PTK was performed for each eye that was included in this study. The mean ablation amount was 117.8 ± 24.4 µm and 83.5 ± 45.7 µm in MCD and GCD, respectively, (p=0.18). The postoperative improvement of the mean VA was similar between the two groups before recurrences (p>0.43) and after recurrences (p>0.71). There were no statistically significant differences in the recurrence rate and the recurrence-free period for any recurrence type. Conclusion: PTK was an effective, safe, and minimally invasive procedure for patients with MCD and GCD. PTK in conjunction with MMC was similarly effective for both groups in terms of recurrence and visual outcomes.Conselho Brasileiro de Oftalmologia2016-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000200069Arquivos Brasileiros de Oftalmologia v.79 n.2 2016reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20160022info:eu-repo/semantics/openAccessYuksel,ErdemCubuk,Mehmet OzgurEroglu,Hulya YazıcıBilgihan,Kamileng2016-05-18T00:00:00Zoai:scielo:S0004-27492016000200069Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2016-05-18T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
title Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
spellingShingle Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
Yuksel,Erdem
Photorefractive keratectomy
Corneal dystrophies
Cornea physiopathology
Mitomycin
Visual acuity
title_short Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
title_full Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
title_fullStr Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
title_full_unstemmed Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
title_sort Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies
author Yuksel,Erdem
author_facet Yuksel,Erdem
Cubuk,Mehmet Ozgur
Eroglu,Hulya Yazıcı
Bilgihan,Kamil
author_role author
author2 Cubuk,Mehmet Ozgur
Eroglu,Hulya Yazıcı
Bilgihan,Kamil
author2_role author
author
author
dc.contributor.author.fl_str_mv Yuksel,Erdem
Cubuk,Mehmet Ozgur
Eroglu,Hulya Yazıcı
Bilgihan,Kamil
dc.subject.por.fl_str_mv Photorefractive keratectomy
Corneal dystrophies
Cornea physiopathology
Mitomycin
Visual acuity
topic Photorefractive keratectomy
Corneal dystrophies
Cornea physiopathology
Mitomycin
Visual acuity
description ABSTRACT Purpose: To evaluate the visual outcomes, recurrence patterns, safety, and efficacy of excimer laser phototherapeutic keratectomy (PTK) in conjunction with mitomycin C (MMC) for corneal macular and granular diystrophies. Methods: The patients were divided into two groups. Group 1 included patients with macular corneal dystrophy (MCD) that caused superficial corneal plaque opacities, and Group 2 included patients with granular corneal dystrophy (GCD). Patients in both groups were pre-, peri-, and postoperatively evaluated. The groups were compared in terms of uncorrected visual acuity (VA), best spectacle-corrected VA, presence of mild or significant recurrence, and time of recurrence. Results: Eighteen eyes (nine with MCD and nine with GCD) of 18 patients (10 men and eight women) were included. PTK was performed for each eye that was included in this study. The mean ablation amount was 117.8 ± 24.4 µm and 83.5 ± 45.7 µm in MCD and GCD, respectively, (p=0.18). The postoperative improvement of the mean VA was similar between the two groups before recurrences (p>0.43) and after recurrences (p>0.71). There were no statistically significant differences in the recurrence rate and the recurrence-free period for any recurrence type. Conclusion: PTK was an effective, safe, and minimally invasive procedure for patients with MCD and GCD. PTK in conjunction with MMC was similarly effective for both groups in terms of recurrence and visual outcomes.
publishDate 2016
dc.date.none.fl_str_mv 2016-04-01
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dc.relation.none.fl_str_mv 10.5935/0004-2749.20160022
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dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.79 n.2 2016
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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