Management of necrotizing scleritis after pterygium surgery with rituximab

Detalhes bibliográficos
Autor(a) principal: Fidelix,Tania Sales de Alencar
Data de Publicação: 2016
Outros Autores: Vieira,Luis Antonio, Trevisani,Virginia Fernandes Moca
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500339
Resumo: ABSTRACT The authors present a case of necrotizing scleritis after pterygium excision successfully treated with rituximab after attempts with high doses of corticosteroids and immunosuppressive drugs. A literature review revealed case reports and a phase I/II dose-ranging randomized clinical trial using rituximab for necrotizing scleritis with or without association with autoimmune disease. This is the only case report on rituximab treatment for necrotizing scleritis after pterygium surgery. In cases with refractoriness to immunosuppressive drugs, a CD20 antibody can be used.
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spelling Management of necrotizing scleritis after pterygium surgery with rituximabScleritisPterygium/surgeryRituximab/therapeutic useAntibodies, monoclonal/administration and dosageABSTRACT The authors present a case of necrotizing scleritis after pterygium excision successfully treated with rituximab after attempts with high doses of corticosteroids and immunosuppressive drugs. A literature review revealed case reports and a phase I/II dose-ranging randomized clinical trial using rituximab for necrotizing scleritis with or without association with autoimmune disease. This is the only case report on rituximab treatment for necrotizing scleritis after pterygium surgery. In cases with refractoriness to immunosuppressive drugs, a CD20 antibody can be used.Conselho Brasileiro de Oftalmologia2016-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500339Arquivos Brasileiros de Oftalmologia v.79 n.5 2016reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20160097info:eu-repo/semantics/openAccessFidelix,Tania Sales de AlencarVieira,Luis AntonioTrevisani,Virginia Fernandes Mocaeng2016-11-30T00:00:00Zoai:scielo:S0004-27492016000500339Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2016-11-30T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Management of necrotizing scleritis after pterygium surgery with rituximab
title Management of necrotizing scleritis after pterygium surgery with rituximab
spellingShingle Management of necrotizing scleritis after pterygium surgery with rituximab
Fidelix,Tania Sales de Alencar
Scleritis
Pterygium/surgery
Rituximab/therapeutic use
Antibodies, monoclonal/administration and dosage
title_short Management of necrotizing scleritis after pterygium surgery with rituximab
title_full Management of necrotizing scleritis after pterygium surgery with rituximab
title_fullStr Management of necrotizing scleritis after pterygium surgery with rituximab
title_full_unstemmed Management of necrotizing scleritis after pterygium surgery with rituximab
title_sort Management of necrotizing scleritis after pterygium surgery with rituximab
author Fidelix,Tania Sales de Alencar
author_facet Fidelix,Tania Sales de Alencar
Vieira,Luis Antonio
Trevisani,Virginia Fernandes Moca
author_role author
author2 Vieira,Luis Antonio
Trevisani,Virginia Fernandes Moca
author2_role author
author
dc.contributor.author.fl_str_mv Fidelix,Tania Sales de Alencar
Vieira,Luis Antonio
Trevisani,Virginia Fernandes Moca
dc.subject.por.fl_str_mv Scleritis
Pterygium/surgery
Rituximab/therapeutic use
Antibodies, monoclonal/administration and dosage
topic Scleritis
Pterygium/surgery
Rituximab/therapeutic use
Antibodies, monoclonal/administration and dosage
description ABSTRACT The authors present a case of necrotizing scleritis after pterygium excision successfully treated with rituximab after attempts with high doses of corticosteroids and immunosuppressive drugs. A literature review revealed case reports and a phase I/II dose-ranging randomized clinical trial using rituximab for necrotizing scleritis with or without association with autoimmune disease. This is the only case report on rituximab treatment for necrotizing scleritis after pterygium surgery. In cases with refractoriness to immunosuppressive drugs, a CD20 antibody can be used.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500339
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500339
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20160097
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.79 n.5 2016
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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