Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials

Detalhes bibliográficos
Autor(a) principal: Andrade,Eric Pinheiro
Data de Publicação: 2016
Outros Autores: Berezovsky,Adriana, Sacai,Paula Yuri, Pereira,Josenilson Martins, Rocha,Daniel Martins, Salomão,Solange Rios
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500294
Resumo: ABSTRACT Purpose: To evaluate visual acuity and transient pattern reversal (PR) visual evoked potentials (VEPs) in the fellow eyes of children with strabismic and/or anisometropic amblyopia. Methods: Children diagnosed with strabismic and/or anisometropic amblyopia were recruited for electrophysiological assessment by VEPs. Monocular grating and optotype acuity were measured using sweep-VEPs and an Early Treatment Diabetic Retinopathy Study chart, respectively. During the same visit, transient PR-VEPs of each eye were recorded using stimuli subtending with a visual angle of 60', 15', and 7.5'. Parameters of amplitude (in μV) and latency (in ms) were determined from VEP recordings. Results: A group of 40 strabismic and/or anisometropic amblyopic children (22 females: 55%, mean age= 8.7 ± 2.2 years, median= 8 years) was examined. A control group of 19 healthy children (13 females: 68.4%, mean age= 8.2 ± 2.6 years, median= 8 years) was also included. The fellow eyes of all amblyopes had significantly worse optotype acuity (p=0.021) than the control group, regardless of whether they were strabismic (p=0.040) or anisometropic (p=0.048). Overall, grating acuity was significantly worse in the fellow eyes of amblyopes (p=0.016) than in healthy controls. Statistically prolonged latency for visual angles of 15' and 7.5' (p=0.018 and 0.002, respectively) was found in the strabismic group when compared with the control group. For the smaller visual stimulus (7.5'), statistically prolonged latency was found among all fellow eyes of amblyopic children (p<0.001). Conclusions: The fellow eyes of amblyopic children showed worse optotype and grating acuity, with subtle abnormalities in the PR-VEP detected as prolonged latencies for smaller size stimuli when compared with eyes of healthy children. These findings show the deleterious effects of amblyopia in several distinct visual functions, mainly those related to spatial vision.
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spelling Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentialsVisual acuityEvoked potentials, visualElectrophysiologyAmblyopiaRefractive errorsChildABSTRACT Purpose: To evaluate visual acuity and transient pattern reversal (PR) visual evoked potentials (VEPs) in the fellow eyes of children with strabismic and/or anisometropic amblyopia. Methods: Children diagnosed with strabismic and/or anisometropic amblyopia were recruited for electrophysiological assessment by VEPs. Monocular grating and optotype acuity were measured using sweep-VEPs and an Early Treatment Diabetic Retinopathy Study chart, respectively. During the same visit, transient PR-VEPs of each eye were recorded using stimuli subtending with a visual angle of 60', 15', and 7.5'. Parameters of amplitude (in μV) and latency (in ms) were determined from VEP recordings. Results: A group of 40 strabismic and/or anisometropic amblyopic children (22 females: 55%, mean age= 8.7 ± 2.2 years, median= 8 years) was examined. A control group of 19 healthy children (13 females: 68.4%, mean age= 8.2 ± 2.6 years, median= 8 years) was also included. The fellow eyes of all amblyopes had significantly worse optotype acuity (p=0.021) than the control group, regardless of whether they were strabismic (p=0.040) or anisometropic (p=0.048). Overall, grating acuity was significantly worse in the fellow eyes of amblyopes (p=0.016) than in healthy controls. Statistically prolonged latency for visual angles of 15' and 7.5' (p=0.018 and 0.002, respectively) was found in the strabismic group when compared with the control group. For the smaller visual stimulus (7.5'), statistically prolonged latency was found among all fellow eyes of amblyopic children (p<0.001). Conclusions: The fellow eyes of amblyopic children showed worse optotype and grating acuity, with subtle abnormalities in the PR-VEP detected as prolonged latencies for smaller size stimuli when compared with eyes of healthy children. These findings show the deleterious effects of amblyopia in several distinct visual functions, mainly those related to spatial vision.Conselho Brasileiro de Oftalmologia2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500294Arquivos Brasileiros de Oftalmologia v.79 n.5 2016reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.5935/0004-2749.20160085info:eu-repo/semantics/openAccessAndrade,Eric PinheiroBerezovsky,AdrianaSacai,Paula YuriPereira,Josenilson MartinsRocha,Daniel MartinsSalomão,Solange Rioseng2016-11-30T00:00:00Zoai:scielo:S0004-27492016000500294Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2016-11-30T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
title Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
spellingShingle Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
Andrade,Eric Pinheiro
Visual acuity
Evoked potentials, visual
Electrophysiology
Amblyopia
Refractive errors
Child
title_short Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
title_full Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
title_fullStr Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
title_full_unstemmed Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
title_sort Dysfunction in the fellow eyes of strabismic and anisometropic amblyopic children assessed by visually evoked potentials
author Andrade,Eric Pinheiro
author_facet Andrade,Eric Pinheiro
Berezovsky,Adriana
Sacai,Paula Yuri
Pereira,Josenilson Martins
Rocha,Daniel Martins
Salomão,Solange Rios
author_role author
author2 Berezovsky,Adriana
Sacai,Paula Yuri
Pereira,Josenilson Martins
Rocha,Daniel Martins
Salomão,Solange Rios
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Andrade,Eric Pinheiro
Berezovsky,Adriana
Sacai,Paula Yuri
Pereira,Josenilson Martins
Rocha,Daniel Martins
Salomão,Solange Rios
dc.subject.por.fl_str_mv Visual acuity
Evoked potentials, visual
Electrophysiology
Amblyopia
Refractive errors
Child
topic Visual acuity
Evoked potentials, visual
Electrophysiology
Amblyopia
Refractive errors
Child
description ABSTRACT Purpose: To evaluate visual acuity and transient pattern reversal (PR) visual evoked potentials (VEPs) in the fellow eyes of children with strabismic and/or anisometropic amblyopia. Methods: Children diagnosed with strabismic and/or anisometropic amblyopia were recruited for electrophysiological assessment by VEPs. Monocular grating and optotype acuity were measured using sweep-VEPs and an Early Treatment Diabetic Retinopathy Study chart, respectively. During the same visit, transient PR-VEPs of each eye were recorded using stimuli subtending with a visual angle of 60', 15', and 7.5'. Parameters of amplitude (in μV) and latency (in ms) were determined from VEP recordings. Results: A group of 40 strabismic and/or anisometropic amblyopic children (22 females: 55%, mean age= 8.7 ± 2.2 years, median= 8 years) was examined. A control group of 19 healthy children (13 females: 68.4%, mean age= 8.2 ± 2.6 years, median= 8 years) was also included. The fellow eyes of all amblyopes had significantly worse optotype acuity (p=0.021) than the control group, regardless of whether they were strabismic (p=0.040) or anisometropic (p=0.048). Overall, grating acuity was significantly worse in the fellow eyes of amblyopes (p=0.016) than in healthy controls. Statistically prolonged latency for visual angles of 15' and 7.5' (p=0.018 and 0.002, respectively) was found in the strabismic group when compared with the control group. For the smaller visual stimulus (7.5'), statistically prolonged latency was found among all fellow eyes of amblyopic children (p<0.001). Conclusions: The fellow eyes of amblyopic children showed worse optotype and grating acuity, with subtle abnormalities in the PR-VEP detected as prolonged latencies for smaller size stimuli when compared with eyes of healthy children. These findings show the deleterious effects of amblyopia in several distinct visual functions, mainly those related to spatial vision.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500294
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500294
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0004-2749.20160085
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.79 n.5 2016
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
instacron_str CBO
institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
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