Pattern-reversal electroretinograms for the diagnosis and management of disorders of the anterior visual pathway

• Autor(a) principal: Hokazono,Kenzo
• Data de Publicação: 2011
• Outros Autores: Oyamada,Maria Kiyoko, Monteiro,Mário Luiz Ribeiro
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Arquivos brasileiros de oftalmologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492011000300017
• topic: Electroretinography/methods; Optic nerve injuries; Retina/physiopathology; Optic nerve diseases/diagnosis; Pattern recognition, visual; Vision Disorders/diagnosis; Visual Pathways/pathology

The pattern electroretinogram is an electrophysiological test that assesses the function of inner retinal layers, particularly the ganglion cells layer of retina, using a reversing checkerboard or grating pattern that produces no change in average luminance over time. The normal pattern electroretinogram is composed of a proeminent positive component (P50) and a large later negative component (N95). Since structural damage that compromises the retinal ganglion cell layer can lead to pattern electroretinogram changes, particularly in the N95 amplitude, the test can be useful in the treatment of a number of anterior visual pathway diseases. In this article, we review the methods for recording pattern electroretinogram and its usefulness in the diagnosis and management of diseases including inflammatory, hereditary, ischemic and compressive lesions of the anterior visual pathway.