Influence of patient race on the outcome of photorefractive keratectomy for myopia correction

Detalhes bibliográficos
Autor(a) principal: Cresta,Fernando Betty
Data de Publicação: 2002
Outros Autores: MA,Steven, LaBree,Lauree D., McDonnell,Peter J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos brasileiros de oftalmologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492002000200014
Resumo: Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon- fluoride excimer laser (VISX) with 160 mJ/cm² fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was alpha = 0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01) and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: --0.55 (± 0.88) and 0.97 (± 0.79); --0.75 (± 1.24) and 0.40 (± 0.45); --1.21 (± 2.55) and 0.75 (± 0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.
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spelling Influence of patient race on the outcome of photorefractive keratectomy for myopia correctionMyopia/surgeryRefraction errorsKeratectomy photorefractive for excimer laserRacial stocksPurpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon- fluoride excimer laser (VISX) with 160 mJ/cm² fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was alpha = 0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01) and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: --0.55 (± 0.88) and 0.97 (± 0.79); --0.75 (± 1.24) and 0.40 (± 0.45); --1.21 (± 2.55) and 0.75 (± 0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.Conselho Brasileiro de Oftalmologia2002-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492002000200014Arquivos Brasileiros de Oftalmologia v.65 n.2 2002reponame:Arquivos brasileiros de oftalmologia (Online)instname:Conselho Brasileiro de Oftalmologia (CBO)instacron:CBO10.1590/S0004-27492002000200014info:eu-repo/semantics/openAccessCresta,Fernando BettyMA,StevenLaBree,Lauree D.McDonnell,Peter J.eng2002-08-05T00:00:00Zoai:scielo:S0004-27492002000200014Revistahttp://aboonline.org.br/https://old.scielo.br/oai/scielo-oai.phpaboonline@cbo.com.br||abo@cbo.com.br1678-29250004-2749opendoar:2002-08-05T00:00Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)false
dc.title.none.fl_str_mv Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
title Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
spellingShingle Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
Cresta,Fernando Betty
Myopia/surgery
Refraction errors
Keratectomy photorefractive for excimer laser
Racial stocks
title_short Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
title_full Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
title_fullStr Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
title_full_unstemmed Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
title_sort Influence of patient race on the outcome of photorefractive keratectomy for myopia correction
author Cresta,Fernando Betty
author_facet Cresta,Fernando Betty
MA,Steven
LaBree,Lauree D.
McDonnell,Peter J.
author_role author
author2 MA,Steven
LaBree,Lauree D.
McDonnell,Peter J.
author2_role author
author
author
dc.contributor.author.fl_str_mv Cresta,Fernando Betty
MA,Steven
LaBree,Lauree D.
McDonnell,Peter J.
dc.subject.por.fl_str_mv Myopia/surgery
Refraction errors
Keratectomy photorefractive for excimer laser
Racial stocks
topic Myopia/surgery
Refraction errors
Keratectomy photorefractive for excimer laser
Racial stocks
description Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon- fluoride excimer laser (VISX) with 160 mJ/cm² fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was alpha = 0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectacle-corrected visual acuity of 20/15 (p=0.01) and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: --0.55 (± 0.88) and 0.97 (± 0.79); --0.75 (± 1.24) and 0.40 (± 0.45); --1.21 (± 2.55) and 0.75 (± 0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.
publishDate 2002
dc.date.none.fl_str_mv 2002-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492002000200014
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 10.1590/S0004-27492002000200014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Oftalmologia v.65 n.2 2002
reponame:Arquivos brasileiros de oftalmologia (Online)
instname:Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
instname_str Conselho Brasileiro de Oftalmologia (CBO)
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institution CBO
reponame_str Arquivos brasileiros de oftalmologia (Online)
collection Arquivos brasileiros de oftalmologia (Online)
repository.name.fl_str_mv Arquivos brasileiros de oftalmologia (Online) - Conselho Brasileiro de Oftalmologia (CBO)
repository.mail.fl_str_mv aboonline@cbo.com.br||abo@cbo.com.br
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