Anthelmintic effect of Cassia fistula and Combretum leprosum protein fractions against goat gastrointestinal nematodes

• Autor(a) principal: Silva,Mara Thais de Oliveira
• Data de Publicação: 2018
• Outros Autores: Maia,Mara Andrade Colares, Silva,Michele Dalvina Correia da, Torres,Taffarel Melo, Pereira,José Carlos da Silveira, Araújo,João Ronielly Campêlo, Silva,Ryan Emiliano da, Souza,Anna Lopes da Costa, Barbosa,Tallyson Nogueira, Bezerra,Ana Carla Diógenes Suassuna
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Brasileira de Parasitologia Veterinária (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612018000200237
• topic: Phytotherapy; Cassia fistula L.; Combretum leprosum Mart.; larvicidal activity; ovicidal activity

Abstract In this study, we evaluated the ovicidal and larvicidal activity of protein preparations obtained from Cassia fistula L. and Combretum leprosum Mart. leaves on the gastrointestinal parasites of goats. Protein preparations were obtained after the extraction of C. fistula L. and C. leprosum Mart. leaves, followed by protein fractionation (with ammonium sulfate saturation percentages of 30%, 30%-60%, and 60%-90%) and dialysis, which resulted in protein fractions (called F1, F2, and F3, respectively). The fractions were evaluated by egg hatching (the eggs were recovered in stool samples from naturally infected goats) and larval development tests. The results reveled that the inhibition of hatching of eggs caused by the protein fractions of C. fistula (38%) were similar to that of the control drug, thiabendazole. In addition, the fractions of C. fistula caused significant inhibition (61-69%) of larval development also. However, C. leprosum did not reveal significant inhibition of egg hatching and larval development. We conclude that C. fistula L. showed better ovicidal and larvicidal activity against endoparasites.