Efficacy of afoxolaner in the flea control in experimentally infested cats
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Parasitologia Veterinária (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612019000400760 |
Resumo: | Abstract The aim of this study was to evaluate the efficacy of a single dose of oral afoxolaner in controlling fleas in cats. Fourteen cats were used. The cats were given identification numbers, housed individually, artificially infested with Ctenocephalides felis felis, and treated (or not) with afoxolaner. Were divided into a treatment group and a control group (n = 7/group), on the basis of the fleas count hours after an infestation applied on Day (one-by-one allocation after ordering by count). At the start of the experimental protocol (designated day 0), the treated group received afoxolaner in a single dose of 2.5 mg/kg and the control group animals received a placebo. All animals were infested with 100 C. felis felis fleas two days before day 0, as well as on days 5, 12, 19, 26, 33, 40, 47, 54, and 63, parasite loads being evaluated at 48 h after each infestation. The efficacy of afoxolaner was 100% on day 2 and remained above 98% until day 42, decreasing to 95.3% by day 63. The findings confirm that a single dose of oral afoxolaner was effective in controlling C. felis felis in cats, and there were no observed adverse events. |
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Efficacy of afoxolaner in the flea control in experimentally infested catsDermatopathiesCtenocephalides felis felistreatmentAbstract The aim of this study was to evaluate the efficacy of a single dose of oral afoxolaner in controlling fleas in cats. Fourteen cats were used. The cats were given identification numbers, housed individually, artificially infested with Ctenocephalides felis felis, and treated (or not) with afoxolaner. Were divided into a treatment group and a control group (n = 7/group), on the basis of the fleas count hours after an infestation applied on Day (one-by-one allocation after ordering by count). At the start of the experimental protocol (designated day 0), the treated group received afoxolaner in a single dose of 2.5 mg/kg and the control group animals received a placebo. All animals were infested with 100 C. felis felis fleas two days before day 0, as well as on days 5, 12, 19, 26, 33, 40, 47, 54, and 63, parasite loads being evaluated at 48 h after each infestation. The efficacy of afoxolaner was 100% on day 2 and remained above 98% until day 42, decreasing to 95.3% by day 63. The findings confirm that a single dose of oral afoxolaner was effective in controlling C. felis felis in cats, and there were no observed adverse events.Colégio Brasileiro de Parasitologia Veterinária2019-12-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612019000400760Revista Brasileira de Parasitologia Veterinária v.28 n.4 2019reponame:Revista Brasileira de Parasitologia Veterinária (Online)instname:Colégio Brasileiro de Parasitologia Veterinária (CBPV)instacron:CBPV10.1590/s1984-29612019064info:eu-repo/semantics/openAccessMachado,Marília AlvesCampos,Diefrey RibeiroLopes,Natália LôresBastos,Isabela Pessôa BarbieriAlves,Mariana Silva RevoredoCorreia,Thais RibeiroScott,Fabio BarbourFernandes,Julio Israeleng2020-04-14T00:00:00Zoai:scielo:S1984-29612019000400760Revistahttp://www.scielo.br/scielo.php?script=sci_serial&lng=pt&pid=1984-2961https://old.scielo.br/oai/scielo-oai.php||zacariascbpv@fcav.unesp.br1984-29610103-846Xopendoar:2020-04-14T00:00Revista Brasileira de Parasitologia Veterinária (Online) - Colégio Brasileiro de Parasitologia Veterinária (CBPV)false |
dc.title.none.fl_str_mv |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
title |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
spellingShingle |
Efficacy of afoxolaner in the flea control in experimentally infested cats Machado,Marília Alves Dermatopathies Ctenocephalides felis felis treatment |
title_short |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
title_full |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
title_fullStr |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
title_full_unstemmed |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
title_sort |
Efficacy of afoxolaner in the flea control in experimentally infested cats |
author |
Machado,Marília Alves |
author_facet |
Machado,Marília Alves Campos,Diefrey Ribeiro Lopes,Natália Lôres Bastos,Isabela Pessôa Barbieri Alves,Mariana Silva Revoredo Correia,Thais Ribeiro Scott,Fabio Barbour Fernandes,Julio Israel |
author_role |
author |
author2 |
Campos,Diefrey Ribeiro Lopes,Natália Lôres Bastos,Isabela Pessôa Barbieri Alves,Mariana Silva Revoredo Correia,Thais Ribeiro Scott,Fabio Barbour Fernandes,Julio Israel |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Machado,Marília Alves Campos,Diefrey Ribeiro Lopes,Natália Lôres Bastos,Isabela Pessôa Barbieri Alves,Mariana Silva Revoredo Correia,Thais Ribeiro Scott,Fabio Barbour Fernandes,Julio Israel |
dc.subject.por.fl_str_mv |
Dermatopathies Ctenocephalides felis felis treatment |
topic |
Dermatopathies Ctenocephalides felis felis treatment |
description |
Abstract The aim of this study was to evaluate the efficacy of a single dose of oral afoxolaner in controlling fleas in cats. Fourteen cats were used. The cats were given identification numbers, housed individually, artificially infested with Ctenocephalides felis felis, and treated (or not) with afoxolaner. Were divided into a treatment group and a control group (n = 7/group), on the basis of the fleas count hours after an infestation applied on Day (one-by-one allocation after ordering by count). At the start of the experimental protocol (designated day 0), the treated group received afoxolaner in a single dose of 2.5 mg/kg and the control group animals received a placebo. All animals were infested with 100 C. felis felis fleas two days before day 0, as well as on days 5, 12, 19, 26, 33, 40, 47, 54, and 63, parasite loads being evaluated at 48 h after each infestation. The efficacy of afoxolaner was 100% on day 2 and remained above 98% until day 42, decreasing to 95.3% by day 63. The findings confirm that a single dose of oral afoxolaner was effective in controlling C. felis felis in cats, and there were no observed adverse events. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612019000400760 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612019000400760 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1984-29612019064 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Colégio Brasileiro de Parasitologia Veterinária |
publisher.none.fl_str_mv |
Colégio Brasileiro de Parasitologia Veterinária |
dc.source.none.fl_str_mv |
Revista Brasileira de Parasitologia Veterinária v.28 n.4 2019 reponame:Revista Brasileira de Parasitologia Veterinária (Online) instname:Colégio Brasileiro de Parasitologia Veterinária (CBPV) instacron:CBPV |
instname_str |
Colégio Brasileiro de Parasitologia Veterinária (CBPV) |
instacron_str |
CBPV |
institution |
CBPV |
reponame_str |
Revista Brasileira de Parasitologia Veterinária (Online) |
collection |
Revista Brasileira de Parasitologia Veterinária (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Parasitologia Veterinária (Online) - Colégio Brasileiro de Parasitologia Veterinária (CBPV) |
repository.mail.fl_str_mv |
||zacariascbpv@fcav.unesp.br |
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1754208918354001920 |