The role of neuroimaging in the determination of brain death

Detalhes bibliográficos
Autor(a) principal: Corrêa,Diogo Goulart
Data de Publicação: 2022
Outros Autores: Souza,Simone Rachid de, Nunes,Paulo Glukhas Cassar, Coutinho Jr.,Antonio Carlos, Cruz Jr.,Luiz Celso Hygino da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Radiologia Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000600365
Resumo: Abstract Brain death is the irreversible cessation of all brain function. Although protocols for its determination vary among countries, the concept of brain death is widely accepted, despite ethical and religious issues. The pathophysiology of brain death is related to hypoxia and ischemia in the setting of extensive brain injury. It is also related to the effects of brain edema, which increases intracranial pressure, leading to cerebral circulatory arrest. Although the diagnosis of brain death is based on clinical parameters, the use of neuroimaging to demonstrate diffuse brain injury as the cause of coma prior to definitive clinical examination is a prerequisite. Brain computed tomography (CT) and magnetic resonance imaging (MRI) demonstrate diffuse edema, as well as ventricular and sulcal effacement, together with brain herniation. Angiography (by CT or MRI) demonstrates the absence of intracranial arterial and venous flow. In some countries, electroencephalography, cerebral digital subtraction angiography, transcranial Doppler ultrasound, or scintigraphy/single-photon emission CT are currently used for the definitive diagnosis of brain death. Although the definition of brain death relies on clinical features, radiologists could play an important role in the early recognition of global hypoxic–ischemic injury and the absence of cerebral vascular perfusion.
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spelling The role of neuroimaging in the determination of brain deathBrain deathTomography, X-ray computedComputed tomography angiographyMagnetic resonance imagingMagnetic resonance angiographyAbstract Brain death is the irreversible cessation of all brain function. Although protocols for its determination vary among countries, the concept of brain death is widely accepted, despite ethical and religious issues. The pathophysiology of brain death is related to hypoxia and ischemia in the setting of extensive brain injury. It is also related to the effects of brain edema, which increases intracranial pressure, leading to cerebral circulatory arrest. Although the diagnosis of brain death is based on clinical parameters, the use of neuroimaging to demonstrate diffuse brain injury as the cause of coma prior to definitive clinical examination is a prerequisite. Brain computed tomography (CT) and magnetic resonance imaging (MRI) demonstrate diffuse edema, as well as ventricular and sulcal effacement, together with brain herniation. Angiography (by CT or MRI) demonstrates the absence of intracranial arterial and venous flow. In some countries, electroencephalography, cerebral digital subtraction angiography, transcranial Doppler ultrasound, or scintigraphy/single-photon emission CT are currently used for the definitive diagnosis of brain death. Although the definition of brain death relies on clinical features, radiologists could play an important role in the early recognition of global hypoxic–ischemic injury and the absence of cerebral vascular perfusion.Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem2022-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000600365Radiologia Brasileira v.55 n.6 2022reponame:Radiologia Brasileira (Online)instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)instacron:CBR10.1590/0100-3984.2022.0016info:eu-repo/semantics/openAccessCorrêa,Diogo GoulartSouza,Simone Rachid deNunes,Paulo Glukhas CassarCoutinho Jr.,Antonio CarlosCruz Jr.,Luiz Celso Hygino daeng2022-12-16T00:00:00Zoai:scielo:S0100-39842022000600365Revistahttps://www.scielo.br/j/rb/https://old.scielo.br/oai/scielo-oai.phpradiologiabrasileira@cbr.org.br1678-70990100-3984opendoar:2022-12-16T00:00Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)false
dc.title.none.fl_str_mv The role of neuroimaging in the determination of brain death
title The role of neuroimaging in the determination of brain death
spellingShingle The role of neuroimaging in the determination of brain death
Corrêa,Diogo Goulart
Brain death
Tomography, X-ray computed
Computed tomography angiography
Magnetic resonance imaging
Magnetic resonance angiography
title_short The role of neuroimaging in the determination of brain death
title_full The role of neuroimaging in the determination of brain death
title_fullStr The role of neuroimaging in the determination of brain death
title_full_unstemmed The role of neuroimaging in the determination of brain death
title_sort The role of neuroimaging in the determination of brain death
author Corrêa,Diogo Goulart
author_facet Corrêa,Diogo Goulart
Souza,Simone Rachid de
Nunes,Paulo Glukhas Cassar
Coutinho Jr.,Antonio Carlos
Cruz Jr.,Luiz Celso Hygino da
author_role author
author2 Souza,Simone Rachid de
Nunes,Paulo Glukhas Cassar
Coutinho Jr.,Antonio Carlos
Cruz Jr.,Luiz Celso Hygino da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Corrêa,Diogo Goulart
Souza,Simone Rachid de
Nunes,Paulo Glukhas Cassar
Coutinho Jr.,Antonio Carlos
Cruz Jr.,Luiz Celso Hygino da
dc.subject.por.fl_str_mv Brain death
Tomography, X-ray computed
Computed tomography angiography
Magnetic resonance imaging
Magnetic resonance angiography
topic Brain death
Tomography, X-ray computed
Computed tomography angiography
Magnetic resonance imaging
Magnetic resonance angiography
description Abstract Brain death is the irreversible cessation of all brain function. Although protocols for its determination vary among countries, the concept of brain death is widely accepted, despite ethical and religious issues. The pathophysiology of brain death is related to hypoxia and ischemia in the setting of extensive brain injury. It is also related to the effects of brain edema, which increases intracranial pressure, leading to cerebral circulatory arrest. Although the diagnosis of brain death is based on clinical parameters, the use of neuroimaging to demonstrate diffuse brain injury as the cause of coma prior to definitive clinical examination is a prerequisite. Brain computed tomography (CT) and magnetic resonance imaging (MRI) demonstrate diffuse edema, as well as ventricular and sulcal effacement, together with brain herniation. Angiography (by CT or MRI) demonstrates the absence of intracranial arterial and venous flow. In some countries, electroencephalography, cerebral digital subtraction angiography, transcranial Doppler ultrasound, or scintigraphy/single-photon emission CT are currently used for the definitive diagnosis of brain death. Although the definition of brain death relies on clinical features, radiologists could play an important role in the early recognition of global hypoxic–ischemic injury and the absence of cerebral vascular perfusion.
publishDate 2022
dc.date.none.fl_str_mv 2022-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000600365
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842022000600365
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0100-3984.2022.0016
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
publisher.none.fl_str_mv Publicação do Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
dc.source.none.fl_str_mv Radiologia Brasileira v.55 n.6 2022
reponame:Radiologia Brasileira (Online)
instname:Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron:CBR
instname_str Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron_str CBR
institution CBR
reponame_str Radiologia Brasileira (Online)
collection Radiologia Brasileira (Online)
repository.name.fl_str_mv Radiologia Brasileira (Online) - Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
repository.mail.fl_str_mv radiologiabrasileira@cbr.org.br
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